{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T10:41:36Z","timestamp":1778582496442,"version":"3.51.4"},"reference-count":24,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Coinfection of ferrets with H5N1 and pH1N1 viruses resulted in two predominate genotypes in the lungs containing surface genes of highly pathogenic avian influenza H5N1 virus in the backbone of pandemic H1N1 2009 (pH1N1). Compared to parental strains, these reassortants exhibited increased growth and virulence\n            <jats:italic>in vitro<\/jats:italic>\n            and in mice but failed to be transmitted indirectly to naive contact ferrets. Thus, this demonstrates a possible natural reassortment following coinfection as well as the pathogenicity of the potential reassortants.\n          <\/jats:p>","DOI":"10.1128\/jvi.01572-15","type":"journal-article","created":{"date-parts":[[2015,10,22]],"date-time":"2015-10-22T15:02:01Z","timestamp":1445526121000},"page":"616-623","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":3,"title":["Growth and Pathogenic Potential of Naturally Selected Reassortants after Coinfection with Pandemic H1N1 and Highly Pathogenic Avian Influenza H5N1 Viruses"],"prefix":"10.1128","volume":"90","author":[{"given":"Min-Suk","family":"Song","sequence":"first","affiliation":[{"name":"College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun Hee","family":"Baek","sequence":"additional","affiliation":[{"name":"College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe Noriel Q.","family":"Pascua","sequence":"additional","affiliation":[{"name":"College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeok-il","family":"Kwon","sequence":"additional","affiliation":[{"name":"College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun-Ha","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su-Jin","family":"Park","sequence":"additional","affiliation":[{"name":"College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Se Mi","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Il","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won-Suk","family":"Choi","sequence":"additional","affiliation":[{"name":"College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eung-Gook","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chul-Joong","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Ki","family":"Choi","sequence":"additional","affiliation":[{"name":"College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0903810"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1176225"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature08182"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00053-10"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1602.091230"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-2659.2012.00337.x"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2010.12.011"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.028662-0"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1189132"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0707279"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2009.124"},{"key":"e_1_3_2_13_2","first-page":"158","article-title":"The pig as a mixing vessel for influenza viruses: human and veterinary implications","volume":"3","author":"Ma W","year":"2008","unstructured":"Ma W, Kahn RE, Richt JA. 2008. 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