{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:14:37Z","timestamp":1787796877298,"version":"build-2784847793"},"reference-count":28,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T00:00:00Z","timestamp":1644364800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,2,9]],"date-time":"2022-02-09T00:00:00Z","timestamp":1644364800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31970501"],"award-info":[{"award-number":["31970501"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2022,2,9]]},"abstract":"<jats:p>The H7 subtype avian influenza viruses, such as H7N2, H7N3, H7N4, H7N7, and H7N9, were documented as being capable of infecting humans, and the H7 subtype low pathogenicity avian influenza viruses are capable of mutating into highly pathogenic avian influenza; therefore, they pose a serious threat to public health. Here, we investigated the evolutionary history, molecular characteristics, and pathogenicity of shorebird-origin influenza A(H7N4) viruses, showing a similar evolutionary trajectory with Jiangsu human A(H7N4) viruses in HA and NA genes.<\/jats:p>","DOI":"10.1128\/jvi.01717-21","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T11:43:32Z","timestamp":1637149412000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":24,"title":["Emergence, Evolution, and Pathogenicity of Influenza A(H7N4) Virus in Shorebirds in China"],"prefix":"10.1128","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7162-2497","authenticated-orcid":true,"given":"Hongliang","family":"Chai","sequence":"first","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Li","sequence":"additional","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghui","family":"Li","sequence":"additional","affiliation":[{"name":"Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinru","family":"Lv","sequence":"additional","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentao","family":"Yu","sequence":"additional","affiliation":[{"name":"Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Li","sequence":"additional","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Sun","sequence":"additional","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulei","family":"Li","sequence":"additional","affiliation":[{"name":"Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heting","family":"Sun","sequence":"additional","affiliation":[{"name":"General Station for Surveillance of Wildlife Disease &amp; Wildlife Borne Diseases, National Forestry and Grassland Administration, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingman","family":"Tian","sequence":"additional","affiliation":[{"name":"Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Xu","sequence":"additional","affiliation":[{"name":"General Station for Surveillance of Wildlife Disease &amp; Wildlife Borne Diseases, National Forestry and Grassland Administration, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoli","family":"Bai","sequence":"additional","affiliation":[{"name":"Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Peng","sequence":"additional","affiliation":[{"name":"General Station for Surveillance of Wildlife Disease &amp; Wildlife Borne Diseases, National Forestry and Grassland Administration, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linhong","family":"Xie","sequence":"additional","affiliation":[{"name":"General Station for Surveillance of Wildlife Disease &amp; Wildlife Borne Diseases, National Forestry and Grassland Administration, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyuan","family":"Qin","sequence":"additional","affiliation":[{"name":"General Station for Surveillance of Wildlife Disease &amp; Wildlife Borne Diseases, National Forestry and Grassland Administration, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"An","sequence":"additional","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengjiang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Liaoning Wildlife Protection and Epidemic Disease Monitoring Center, Dalian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Liaoning Wildlife Protection and Epidemic Disease Monitoring Center, Dalian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Du","sequence":"additional","affiliation":[{"name":"Forestry and Grassland Affairs Service Center, Donggang Forestry and Grassland Administration, Donggang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyuan","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"},{"name":"Heilongjiang Vocational College for Nationalities, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhijun","family":"Hou","sequence":"additional","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangwei","family":"Zeng","sequence":"additional","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulong","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juergen A.","family":"Richt","sequence":"additional","affiliation":[{"name":"Diagnostic Medicine\/Pathobiology, Center of Excellence for Emerging and Zoonotic Animal Diseases (CEEZAD), College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajun","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5345-1580","authenticated-orcid":true,"given":"Yanbing","family":"Li","sequence":"additional","affiliation":[{"name":"Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhang","family":"Ma","sequence":"additional","affiliation":[{"name":"College of Wildlife and Protected Area, Northeast Forestry University, Harbin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.es2014.19.18.20793"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a038349"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01277-17"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02208-16"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2311.171013"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2018.06.002"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.00220"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.9.7626-7631.1998"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1001034"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.000333"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02427-09"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.069542-0"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11262-019-01700-z"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1240532"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2510.190506"},{"key":"e_1_3_3_17_2","volume-title":"Molecular epidemiological study on influenza virus in wild birds of Heilongjiang.","author":"Chai H","year":"2012","unstructured":"Chai H. 2012. Molecular epidemiological study on influenza virus in wild birds of Heilongjiang. PhD thesis. Northeast Forestry University, Harbin, China."},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-8286.2003.00340.x"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molp.2020.06.009"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mst010"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/1755-0998.13096"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msu300"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mst024"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4285"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/ve\/vew007"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/ve\/vey016"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mss084"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1229455"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a118408"}],"container-title":["Journal of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JVI.01717-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JVI.01717-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T11:34:20Z","timestamp":1646480060000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JVI.01717-21"}},"subtitle":[],"editor":[{"given":"Stacey","family":"Schultz-Cherry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,2,9]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,2,9]]}},"alternative-id":["10.1128\/JVI.01717-21"],"URL":"https:\/\/doi.org\/10.1128\/jvi.01717-21","relation":{},"ISSN":["0022-538X","1098-5514"],"issn-type":[{"value":"0022-538X","type":"print"},{"value":"1098-5514","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,9]]},"assertion":[{"value":"2021-10-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01717-21"}}