{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T17:51:35Z","timestamp":1760205095307,"version":"3.41.2"},"reference-count":82,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2021,1,28]],"date-time":"2021-01-28T00:00:00Z","timestamp":1611792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000053","name":"HHS | NIH | National Eye Institute","doi-asserted-by":"publisher","award":["R01EY029677"],"award-info":[{"award-number":["R01EY029677"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"HHS | NIH | National Eye Institute","doi-asserted-by":"publisher","award":["RO1EY024649"],"award-info":[{"award-number":["RO1EY024649"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2021,1,28]]},"abstract":"<jats:p>Innate lymphocytes have plasticity and can change functionality; type 2 innate lymphoid cells (ILC2s) can convert to ILC1 or ILC3 cells or change their activation state to produce IL-17 or IL-10 depending on environmental cues. In this study, we investigated the gene and cytokine profiles of ILC2s, which play a major role in HSV-IL-2-induced CNS demyelination.<\/jats:p>","DOI":"10.1128\/jvi.01934-20","type":"journal-article","created":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T14:32:48Z","timestamp":1605709968000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":1,"title":["Impact of a Demyelination-Inducing Central Nervous System Virus on Expression of Demyelination Genes in Type 2 Lymphoid Cells"],"prefix":"10.1128","volume":"95","author":[{"given":"Satoshi","family":"Hirose","sequence":"first","affiliation":[{"name":"Center for Neurobiology &amp; Vaccine Development, Ophthalmology Research, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihoko","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Biology, Pomona College, Claremont, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kati","family":"Tormanen","sequence":"additional","affiliation":[{"name":"Center for Neurobiology &amp; Vaccine Development, Ophthalmology Research, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedram","family":"Shafiei Jahani","sequence":"additional","affiliation":[{"name":"Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omid","family":"Akbari","sequence":"additional","affiliation":[{"name":"Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3291-1995","authenticated-orcid":true,"given":"Homayon","family":"Ghiasi","sequence":"additional","affiliation":[{"name":"Center for Neurobiology &amp; Vaccine Development, Ophthalmology Research, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.10.040192.001101"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200009283431307"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)63598-2"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.23.021704.115707"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI21357"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200206000-00001"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.16.7440"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1191\/135245899678846311"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.54.1.265"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1997.tb00210.x"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.53.6.1367-a"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510x(93)90032-t"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410240618"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510x(89)90171-8"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410250211"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198810133191517"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.40.2.215"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1991.tb04955.x"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5728(87)90082-8"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(89)90103-7"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410280209"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3083.2002.01132.x"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0304-3940(00)00996-4"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0165-5728(98)00068-x"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-018-2938-1"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2004.12.004"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.08-3211"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.2002.1609"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.19.9029-9036.2001"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02241-13"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature14189"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2014.09.006"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.07.017"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3459"},{"key":"e_1_3_3_36_2","first-page":"45","article-title":"Evaluation of membrane fluidity in cerebral microvasculature","volume":"6","author":"Villacara A","year":"1990","unstructured":"Villacara A, Zanchin G, Spatz M. 1990. Evaluation of membrane fluidity in cerebral microvasculature. Microcirc Endothelium Lymphatics 6:45\u201365.","journal-title":"Microcirc Endothelium Lymphatics"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3365"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20160525"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20130351"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2017.86"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3481"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3448"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1315854111"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18601-7"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature23676"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature23469"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature24029"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2020.101549"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00523-19"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00578-17"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1912839117"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aav7188"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09234-6"},{"key":"e_1_3_3_54_2","first-page":"107","article-title":"Herpesvirus genes: molecular basis of viral replication and pathogenicity","volume":"59","author":"Nishiyama Y","year":"1996","unstructured":"Nishiyama Y. 1996. Herpesvirus genes: molecular basis of viral replication and pathogenicity. Nagoya J Med Sci 59:107\u2013119.","journal-title":"Nagoya J Med Sci"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.21.11307"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-68-1-19"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.imlet.2016.01.007"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2015.21"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1962"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a016337"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-019-0521-4"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20190460"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.08.040190.003051"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0016820"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1038\/gt.2011.32"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.76.18.9069-9078.2002"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3344"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3719"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20170545"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2017.12.013"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2714"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2545"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0607038104"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.107772"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-020-0282-9"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.10.015"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23552"},{"key":"e_1_3_3_78_2","first-page":"11","article-title":"Managing toxicities of high-dose interleukin-2","volume":"16","author":"Schwartz RN","year":"2002","unstructured":"Schwartz RN, Stover L, Dutcher JP. 2002. Managing toxicities of high-dose interleukin-2. Oncology (Williston Park) 16:11\u201320.","journal-title":"Oncology (Williston Park)"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.68.12.8045-8055.1994"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.08.034"},{"key":"e_1_3_3_81_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.11.102"},{"key":"e_1_3_3_82_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts635"},{"key":"e_1_3_3_83_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-12-323"}],"container-title":["Journal of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JVI.01934-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/JVI.01934-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T15:10:03Z","timestamp":1646493003000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/JVI.01934-20"}},"subtitle":[],"editor":[{"given":"Jae U.","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,1,28]]},"references-count":82,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,1,28]]}},"alternative-id":["10.1128\/JVI.01934-20"],"URL":"https:\/\/doi.org\/10.1128\/jvi.01934-20","relation":{},"ISSN":["0022-538X","1098-5514"],"issn-type":[{"type":"print","value":"0022-538X"},{"type":"electronic","value":"1098-5514"}],"subject":[],"published":{"date-parts":[[2021,1,28]]},"assertion":[{"value":"2020-09-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01934-20"}}