{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T13:17:35Z","timestamp":1781011055525,"version":"3.54.1"},"reference-count":29,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2009,4,15]],"date-time":"2009-04-15T00:00:00Z","timestamp":1239753600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2009,4,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>The rubella virus (RUBV) capsid (C) protein rescues mutants with a lethal deletion between two in-frame NotI sites in the P150 replicase gene, a deletion encompassing nucleotides 1685 to 2192 of the RUBV genome and amino acids (aa) 548 to 717 of P150 (which has a total length of 1,301 aa). The complete domain rescuable by the C protein was mapped to aa 497 to 803 of P150. Introduction of aa 1 to 277 of the C protein (lacking the C-terminal E2 signal sequence) between the NotI sites in the P150 gene in a replicon construct yielded a viable construct that synthesized viral RNA with wild-type kinetics, indicating that C and this region of P150 share a common function. Further genetic analysis revealed that an arginine-rich motif between aa 60 and 68 of the C protein was necessary for the rescue of \u0394NotI deletion mutants and substituted for an arginine-rich motif between aa 731 and 735 of the P150 protein when the C protein was introduced into P150. Possible common functions shared by these arginine-rich motifs include RNA binding and interaction with cell proteins.<\/jats:p>","DOI":"10.1128\/jvi.02411-08","type":"journal-article","created":{"date-parts":[[2009,1,29]],"date-time":"2009-01-29T01:45:45Z","timestamp":1233193545000},"page":"3549-3555","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["Functional Replacement of a Domain in the Rubella Virus P150 Replicase Protein by the Virus Capsid Protein"],"prefix":"10.1128","volume":"83","author":[{"given":"Wen-Pin","family":"Tzeng","sequence":"first","affiliation":[{"name":"Department of Biology, Georgia State University, Atlanta, Georgia 30303"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teryl K.","family":"Frey","sequence":"additional","affiliation":[{"name":"Department of Biology, Georgia State University, Atlanta, Georgia 30303"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2004.02.024"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.16.10807-10820.2005"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.12.5569-5576.2000"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.phyto.43.101804.120505"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.8.4314-4322.2004"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkh579"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-3527(08)60328-0"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm542"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1994.tb06586.x"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02732-07"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200401093"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.17.8259"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00820-06"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1261\/rna.2101906"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00147-06"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1702(02)00030-8"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/373573a0"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.9.5743-5751.2005"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-33012-9_15"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2001.tb10796.x"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2005.07.022"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.2001.1088"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.17.9502-9510.2003"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.7.3189-3201.2002"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2005.04.019"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.80.8.3966-3974.2006"},{"key":"e_1_3_2_28_2","first-page":"61","volume":"283","year":"2004","unstructured":"Whelan, S. 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