{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T01:45:34Z","timestamp":1791164734979,"version":"4.1.0"},"reference-count":19,"publisher":"American Society for Microbiology","issue":"19","license":[{"start":{"date-parts":[[2001,10,1]],"date-time":"2001-10-01T00:00:00Z","timestamp":1001894400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2001,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Although alphaviruses have been extensively studied as model systems for the structural organization of enveloped viruses, no structures exist for the phylogenetically distinct eastern equine encephalomyelitis (EEE)-Venezuelan equine encephalomyelitis (VEE) lineage of New World alphaviruses. Here we report the 25-A\u030astructure of VEE virus, obtained from electron cryomicroscopy and image reconstruction. The envelope spike glycoproteins of VEE virus have a T=4 icosahedral arrangement, similar to that observed in Old World Sindbis, Semliki Forest, and Ross River alphaviruses. However, VEE virus has pronounced differences in its nucleocapsid structure relative to nucleocapsid structures repeatedly observed in Old World alphaviruses.<\/jats:p>","DOI":"10.1128\/jvi.75.19.9532-9537.2001","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T06:06:37Z","timestamp":1027749997000},"page":"9532-9537","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":35,"title":["Venezuelan Equine Encephalomyelitis Virus Structure and Its Divergence from Old World Alphaviruses"],"prefix":"10.1128","volume":"75","author":[{"given":"Angel","family":"Paredes","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030,1 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy","family":"Alwell-Warda","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2-->Department of Pathology and the Center for Tropical Diseases2 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott C.","family":"Weaver","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2-->Department of Pathology and the Center for Tropical Diseases2 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wah","family":"Chiu","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->National Center for Macromolecular Imaging, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030,1 and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley J.","family":"Watowich","sequence":"additional","affiliation":[{"name":"<!--label omitted: 3-->the Department of Human Biological Chemistry &amp; Genetics and Sealy Center for Structural Biology,3 University of Texas Medical Branch, Galveston, Texas 77555"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.63.4.862-922.1999"},{"key":"e_1_3_2_3_2","first-page":"19","article-title":"Arbovirus serogroups: definition and geographic distribution","volume":"1","author":"Calisher C. 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M.\n1996\n825\n841\nLippincott-Raven Publishers\nPhiladelphia Pa"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/mr.58.3.491-562.1994"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.66.8.4737-4747.1992"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/320533a0"},{"key":"e_1_3_2_17_2","unstructured":"Weaver\nS. C.\nDalgarno\nL.\nFrey\nT. K.\nHuang\nH. V.\nKinney\nR. M.\nRice\nC. M.\nRoehrig\nJ. T.\nShope\nR. E.\nStrauss\nE. G.\nFamily Togaviridae Virus taxonomy: classification and nomenclature of viruses. Seventh report of the International Committee on Taxonomy of Viruses.\nvan Regenmortel\nM. H. V.\nFauquet\nC. M.\nBishop\nD. H. L.\nCarstens\nE. B.\nEstes\nM. K.\nLemon\nS. M.\nManiloff\nJ.\nMayo\nM. A.\nMcGeogh\nD. J.\nPringle\nC. R.\nWickner\nR. 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