{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T06:01:19Z","timestamp":1769234479504,"version":"3.49.0"},"reference-count":26,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2006,3,1]],"date-time":"2006-03-01T00:00:00Z","timestamp":1141171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Virol"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Using Meta-BASIC, a highly sensitive method for detection of distant similarity between proteins, we have identified another potential PD-(D\/E)XK endonuclease in human herpesvirus 1 (HHV-1) encoded by the\n            <jats:italic>UL24<\/jats:italic>\n            gene. The universal presence of\n            <jats:italic>UL24<\/jats:italic>\n            in completed herpesviral genomes of three major subfamilies,\n            <jats:italic>Alphaherpesvirinae<\/jats:italic>\n            ,\n            <jats:italic>Betaherpesvirinae<\/jats:italic>\n            , and\n            <jats:italic>Gammaherpesvirinae<\/jats:italic>\n            , suggests a fundamental role for this predicted PD-(D\/E)XK endonuclease activity in the viral life cycle.\n          <\/jats:p>","DOI":"10.1128\/jvi.80.5.2575-2577.2006","type":"journal-article","created":{"date-parts":[[2006,2,11]],"date-time":"2006-02-11T01:27:20Z","timestamp":1139621240000},"page":"2575-2577","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":37,"title":["Human Herpesvirus 1\n            <i>UL24<\/i>\n            Gene Encodes a Potential PD-(D\/E)XK Endonuclease"],"prefix":"10.1128","volume":"80","author":[{"given":"\u0141ukasz","family":"Kniz\u0307ewski","sequence":"first","affiliation":[{"name":"Interdisciplinary Centre for Mathematical and Computational Modelling, Warsaw University, 02-106 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Kinch","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute, University of Texas, Southwestern Medical Center, Dallas, Texas 75390"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick V.","family":"Grishin","sequence":"additional","affiliation":[{"name":"Howard Hughes Medical Institute, University of Texas, Southwestern Medical Center, Dallas, Texas 75390"},{"name":"Department of Biochemistry, University of Texas, Southwestern Medical Center, Dallas, Texas 75390"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leszek","family":"Rychlewski","sequence":"additional","affiliation":[{"name":"BioInfoBank Institute, 60-744 Poznan\u0301, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krzysztof","family":"Ginalski","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre for Mathematical and Computational Modelling, Warsaw University, 02-106 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/25.17.3389"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.18.3417"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkh121"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2002.02989.x"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.2174\/1389203033487072"},{"key":"e_1_3_2_7_2","first-page":"69","volume":"3","year":"2001","unstructured":"Bujnicki, J. 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