{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:51:32Z","timestamp":1791474692917,"version":"4.3.4"},"reference-count":102,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T00:00:00Z","timestamp":1624924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T00:00:00Z","timestamp":1624924800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-15-CE15-0017"],"award-info":[{"award-number":["ANR-15-CE15-0017"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004794","name":"Centre National de la Recherche Scientifique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2021,6,29]]},"abstract":"<jats:p>\n                    The pathogenicity of methicillin-resistant\n                    <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n                    (MRSA) strains relies on their ability to produce a wide variety of tightly regulated virulence factors. Current\n                    <jats:italic>in vivo<\/jats:italic>\n                    models to analyze host-pathogen interactions are limited and difficult to manipulate.\n                  <\/jats:p>","DOI":"10.1128\/mbio.00276-21","type":"journal-article","created":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T04:30:40Z","timestamp":1623731440000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":42,"title":["Reactive Oxygen Species-Dependent Innate Immune Mechanisms Control Methicillin-Resistant Staphylococcus aureus Virulence in the\n                    <i>Drosophila<\/i>\n                    Larval Model"],"prefix":"10.1128","volume":"12","author":[{"given":"Elodie","family":"Ramond","sequence":"first","affiliation":[{"name":"Universit\u00e9 de Paris, Paris, France"},{"name":"INSERM U1151, CNRS UMR 8253, Institut Necker-Enfants Malades, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Jamet","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris, Paris, France"},{"name":"INSERM U1151, CNRS UMR 8253, Institut Necker-Enfants Malades, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiongqi","family":"Ding","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris, Paris, France"},{"name":"INSERM U1151, CNRS UMR 8253, Institut Necker-Enfants Malades, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Euphrasie","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris, Paris, France"},{"name":"INSERM U1151, CNRS UMR 8253, Institut Necker-Enfants Malades, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9mence","family":"Bouvier","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris, Paris, France"},{"name":"INSERM U1151, CNRS UMR 8253, Institut Necker-Enfants Malades, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louison","family":"Lallemant","sequence":"additional","affiliation":[{"name":"Cell Imaging Core Facility, Structure F\u00e9d\u00e9rative de Recherche Necker, INSERM US24\/CNRS UMS3633, Paris, France"},{"name":"Imagine, Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyan","family":"He","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris, Paris, France"},{"name":"INSERM U1151, CNRS UMR 8253, Institut Necker-Enfants Malades, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Arbibe","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris, Paris, France"},{"name":"INSERM U1151, CNRS UMR 8253, Institut Necker-Enfants Malades, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7655-9685","authenticated-orcid":true,"given":"Mathieu","family":"Coureuil","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris, Paris, France"},{"name":"INSERM U1151, CNRS UMR 8253, Institut Necker-Enfants Malades, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5243-4861","authenticated-orcid":true,"given":"Alain","family":"Charbit","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris, Paris, France"},{"name":"INSERM U1151, CNRS UMR 8253, Institut Necker-Enfants Malades, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2019.12.007"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.09.79"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2019.01.008"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00020-18"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2012.00937.x"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i27.4418"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2008.10.003"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2012.00033"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.06.049"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00040.2012"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41385-018-0021-8"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fuw042"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2009.07.023"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/1689861"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2018.10.005"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftw060"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.26353-0"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00417-19"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.2.468-475.2001"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.6.3744-3754.2001"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dci.2016.01.016"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1999.00079.x"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dci.2016.02.020"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-2920.2011.02511.x"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01903-13"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2015.140"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.118.300224"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2011.07.012"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad8588"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3074"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dci.2016.01.001"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006277"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2013.00116"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.003970"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.71.6.3540-3550.2003"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1462-5822.2003.00329.x"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0010008"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2008.01129.x"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2009.124"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-9541-7_12"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.27116-0"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2017.11.004"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00088-10"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2012.11.012"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02965-15"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-12-274"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.168.4.1542"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep43889"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.333807"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.029306"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.25.022106.141615"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.177.14.4097-4104.1995"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1117311"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2020.01.008"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2014.12.012"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/0891-5849(89)90066-x"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0030173"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3763"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.25496"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.GPP3-0031-2018"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-842X(99)01691-1"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.femsim.2004.11.003"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2012.00975.x"},{"key":"e_1_3_2_65_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000982"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-15-1145"},{"key":"e_1_3_2_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2019.08.006"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1916820117"},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2009.01.003"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7007-8-152"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.05.014"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2018.04.010"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.3390\/antiox7100130"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2013.04.013"},{"key":"e_1_3_2_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2016.10.023"},{"key":"e_1_3_2_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2020.01.006"},{"key":"e_1_3_2_77_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinsphys.2012.01.008"},{"key":"e_1_3_2_78_2","doi-asserted-by":"crossref","unstructured":"Yu Y Zhan S Tomberlin JK Huang D Cai M Zheng L Yu Z Zhang J. 2019. Dual oxidase gene Duox and Toll-like receptor 3 gene TLR3 in the Toll pathway suppress zoonotic pathogens through regulating the intestinal bacterial community homeostasis in Hermetia illucens L. bioRxiv 27:844696. https:\/\/doi.org\/10.1101\/844696.","DOI":"10.1101\/844696"},{"key":"e_1_3_2_79_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.025544-0"},{"key":"e_1_3_2_80_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1116932108"},{"key":"e_1_3_2_81_2","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2010.178"},{"key":"e_1_3_2_82_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.180.18.4814-4820.1998"},{"key":"e_1_3_2_83_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.000983"},{"key":"e_1_3_2_84_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.183.17.5171-5179.2001"},{"key":"e_1_3_2_85_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1914830117"},{"key":"e_1_3_2_86_2","doi-asserted-by":"publisher","DOI":"10.1086\/491737"},{"key":"e_1_3_2_87_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.12.5992-5995.2005"},{"key":"e_1_3_2_88_2","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftx005"},{"key":"e_1_3_2_89_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.180.23.6082-6089.1998"},{"key":"e_1_3_2_90_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.7.3667-3669.1999"},{"key":"e_1_3_2_91_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.71.4.2208-2217.2003"},{"key":"e_1_3_2_92_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1995.tb02301.x"},{"key":"e_1_3_2_93_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.70.10.6076-6085.2004"},{"key":"e_1_3_2_94_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1005595"},{"key":"e_1_3_2_95_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw1017"},{"key":"e_1_3_2_96_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu153"},{"key":"e_1_3_2_97_2","doi-asserted-by":"publisher","DOI":"10.18632\/aging.101561"},{"key":"e_1_3_2_98_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2015.085"},{"key":"e_1_3_2_99_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-3933-3"},{"key":"e_1_3_2_100_2","doi-asserted-by":"publisher","DOI":"10.21769\/BioProtoc.3017"},{"key":"e_1_3_2_101_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.35.3.852-860.1982"},{"key":"e_1_3_2_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(03)00856-1"},{"key":"e_1_3_2_103_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/17.5.1217"}],"container-title":["mBio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mBio.00276-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mBio.00276-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T22:34:50Z","timestamp":1646692490000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mBio.00276-21"}},"subtitle":[],"editor":[{"given":"Timothy P.","family":"Stinear","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Carmen","family":"Buchrieser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,6,29]]},"references-count":102,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,6,29]]}},"alternative-id":["10.1128\/mBio.00276-21"],"URL":"https:\/\/doi.org\/10.1128\/mbio.00276-21","relation":{},"ISSN":["2150-7511"],"issn-type":[{"value":"2150-7511","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,29]]},"assertion":[{"value":"2021-03-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00276-21"}}