{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:53:49Z","timestamp":1790729629481,"version":"4.1.0"},"reference-count":81,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T00:00:00Z","timestamp":1624924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T00:00:00Z","timestamp":1624924800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2021,6,29]]},"abstract":"<jats:p>Bacterial cells are encased in a PG exoskeleton that helps to maintain cell shape and confers physical protection. To allow bacterial growth and cell separation, PG needs to be continuously remodeled by hydrolytic enzymes that cleave PG at critical sites.<\/jats:p>","DOI":"10.1128\/mbio.00519-21","type":"journal-article","created":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T07:05:41Z","timestamp":1621839941000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["Ser\/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile"],"prefix":"10.1128","volume":"12","author":[{"given":"Transito","family":"Garcia-Garcia","sequence":"first","affiliation":[{"name":"Laboratoire Pathog\u00e9nese des Bact\u00e9ries Ana\u00e9robies, Institut Pasteur, UMR CNRS 2001, Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Poncet","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Cuenot","sequence":"additional","affiliation":[{"name":"Laboratoire Pathog\u00e9nese des Bact\u00e9ries Ana\u00e9robies, Institut Pasteur, UMR CNRS 2001, Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibaut","family":"Douch\u00e9","sequence":"additional","affiliation":[{"name":"Plateforme Prot\u00e9omique, Unit\u00e9 de Technologie et Service Spectrom\u00e9trie de Masse pour la Biologie, CNRS USR 2000, Institut Pasteur, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quentin","family":"Giai Gianetto","sequence":"additional","affiliation":[{"name":"Plateforme Prot\u00e9omique, Unit\u00e9 de Technologie et Service Spectrom\u00e9trie de Masse pour la Biologie, CNRS USR 2000, Institut Pasteur, Paris, France"},{"name":"Hub de Bioinformatique et Statistique, Departement de Biologie Computationelle, USR3756, Institut Pasteur, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3207-9465","authenticated-orcid":true,"given":"Johann","family":"Peltier","sequence":"additional","affiliation":[{"name":"Laboratoire Pathog\u00e9nese des Bact\u00e9ries Ana\u00e9robies, Institut Pasteur, UMR CNRS 2001, Universit\u00e9 de Paris, Paris, France"},{"name":"Universit\u00e9 Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cells (I2BC), Gif-sur-Yvette, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Courtin","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4947-0519","authenticated-orcid":true,"given":"Marie-Pierre","family":"Chapot-Chartier","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariette","family":"Matondo","sequence":"additional","affiliation":[{"name":"Plateforme Prot\u00e9omique, Unit\u00e9 de Technologie et Service Spectrom\u00e9trie de Masse pour la Biologie, CNRS USR 2000, Institut Pasteur, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Dupuy","sequence":"additional","affiliation":[{"name":"Laboratoire Pathog\u00e9nese des Bact\u00e9ries Ana\u00e9robies, Institut Pasteur, UMR CNRS 2001, Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Candela","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Jouy-en-Josas, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8376-7690","authenticated-orcid":true,"given":"Isabelle","family":"Martin-Verstraete","sequence":"additional","affiliation":[{"name":"Laboratoire Pathog\u00e9nese des Bact\u00e9ries Ana\u00e9robies, Institut Pasteur, UMR CNRS 2001, Universit\u00e9 de Paris, Paris, France"},{"name":"Institut Universitaire de France, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.69.4.585-607.2005"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2007.00094.x"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.00331"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-146-2-249"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2007.00099.x"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00022-11"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00397-15"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.52088"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1108323108"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4842"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02622-18"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.12330"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2010.36"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1507760112"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201695028"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.080747-0"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.470716"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2010.12.016"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja208080r"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2016.12.001"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09223-9"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00042-10"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fuv041"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2017.06.010"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-017-0069-3"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2164"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2012.02.004"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.20"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00005-19"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0968-0004(99)01366-3"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-20098-9_4"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.14636"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2003-4-2-r11"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2011.10.003"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.12348"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-2836(03)00579-5"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.2198\/jelectroph.63.25"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsb897"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2005.04560.x"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.T500024-MCP200"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2015.053"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.4.2144-2153.2001"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.5.3442-3446.2001"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3213"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2198"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2002.tb02741.x"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1999.01238.x"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi011640x"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-1723(04)00262-2"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00188-06"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.185.22.6666-6677.2003"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.12335"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.05569-11"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00100"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-019-0393-4"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.259150"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00648-18"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.27878-0"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.REV119.010155"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1005275"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.000404"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2008.12.031"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2002525"},{"key":"e_1_3_2_65_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi401177n"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.14590"},{"key":"e_1_3_2_67_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004275"},{"key":"e_1_3_2_68_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13966"},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.263889"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2007.05.021"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00249-12"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.665091"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.01939"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00272-11"},{"key":"e_1_3_2_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2018.01.013"},{"key":"e_1_3_2_76_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku316"},{"key":"e_1_3_2_77_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1322"},{"key":"e_1_3_2_78_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2016.136"},{"key":"e_1_3_2_79_2","doi-asserted-by":"publisher","DOI":"10.1021\/pr101065j"},{"key":"e_1_3_2_80_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-3676-2_7"},{"key":"e_1_3_2_81_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmicrobiol.2016.77"},{"key":"e_1_3_2_82_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2839"}],"container-title":["mBio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mBio.00519-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mBio.00519-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T22:30:57Z","timestamp":1646692257000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mBio.00519-21"}},"subtitle":[],"editor":[{"given":"Eleftherios T.","family":"Papoutsakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,6,29]]},"references-count":81,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,6,29]]}},"alternative-id":["10.1128\/mBio.00519-21"],"URL":"https:\/\/doi.org\/10.1128\/mbio.00519-21","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.10.29.360313","asserted-by":"object"}]},"ISSN":["2150-7511"],"issn-type":[{"value":"2150-7511","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,29]]},"assertion":[{"value":"2021-03-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00519-21"}}