{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T01:41:10Z","timestamp":1785894070352,"version":"3.56.0"},"reference-count":118,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T00:00:00Z","timestamp":1619481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T00:00:00Z","timestamp":1619481600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI-136523"],"award-info":[{"award-number":["AI-136523"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH-17-1-0481"],"award-info":[{"award-number":["W81XWH-17-1-0481"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["OIA-1736150"],"award-info":[{"award-number":["OIA-1736150"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014731","name":"Global Lyme Alliance","doi-asserted-by":"crossref","award":["GLA-206311"],"award-info":[{"award-number":["GLA-206311"]}],"id":[{"id":"10.13039\/100014731","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2021,4,27]]},"abstract":"<jats:p>\n                    Animals that are natural carriers of pathogens that cause human diseases commonly manifest little or no sickness as a consequence of infection. Examples include the deer mouse,\n                    <jats:named-content content-type=\"genus-species\">Peromyscus leucopus<\/jats:named-content>\n                    , which is a reservoir for Lyme disease and several other disease agents in North America, and some types of bats, which are carriers of viruses with pathogenicity for humans.\n                  <\/jats:p>","DOI":"10.1128\/mbio.00588-21","type":"journal-article","created":{"date-parts":[[2021,4,12]],"date-time":"2021-04-12T10:27:47Z","timestamp":1618223267000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":26,"title":["An Infection-Tolerant Mammalian Reservoir for Several Zoonotic Agents Broadly Counters the Inflammatory Effects of Endotoxin"],"prefix":"10.1128","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5794-4518","authenticated-orcid":true,"given":"Gabriela","family":"Balderrama-Gutierrez","sequence":"first","affiliation":[{"name":"Department of Developmental and Cell Biology, School of Biological Sciences, University of California Irvine, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6218-0452","authenticated-orcid":true,"given":"Ana","family":"Milovic","sequence":"additional","affiliation":[{"name":"Department of Microbiology &amp; Molecular Genetics, School of Medicine, University of California Irvine, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8485-0771","authenticated-orcid":true,"given":"Vanessa J.","family":"Cook","sequence":"additional","affiliation":[{"name":"Department of Microbiology &amp; Molecular Genetics, School of Medicine, University of California Irvine, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2396-6444","authenticated-orcid":true,"given":"M. Nurul","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology, &amp; Pathology, College of Veterinary Medicine &amp; Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0957-4276","authenticated-orcid":true,"given":"Youwen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Drug Discovery &amp; Biomedical Sciences, College of Pharmacy, University of South Carolina, Columbia, South Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8999-8289","authenticated-orcid":true,"given":"Hippokratis","family":"Kiaris","sequence":"additional","affiliation":[{"name":"Peromyscus Genetic Stock Center, University of South Carolina, Columbia, South Carolina, USA"},{"name":"Department of Medicine, School of Medicine, University of California Irvine, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2539-2798","authenticated-orcid":true,"given":"John T.","family":"Belisle","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology, &amp; Pathology, College of Veterinary Medicine &amp; Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4259-6362","authenticated-orcid":true,"given":"Ali","family":"Mortazavi","sequence":"additional","affiliation":[{"name":"Department of Developmental and Cell Biology, School of Biological Sciences, University of California Irvine, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0719-5248","authenticated-orcid":true,"given":"Alan G.","family":"Barbour","sequence":"additional","affiliation":[{"name":"Department of Microbiology &amp; Molecular Genetics, School of Medicine, University of California Irvine, Irvine, California, USA"},{"name":"Department of Medicine, School of Medicine, University of California Irvine, Irvine, California, USA"},{"name":"Department of Ecology &amp; Evolutionary Biology, School of Biological Sciences, University of California Irvine, Irvine, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2016.07.002"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1807870"},{"key":"e_1_3_4_4_2","volume-title":"The mammals of North America","author":"Hall ER","year":"1981","unstructured":"Hall ER. 1981. The mammals of North America, 2nd ed, vol 2. John Wiley and Sons, New York, NY.","edition":"2"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.2307\/3503904"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115306"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.7589\/0090-3558-33.4.766"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.57.11.3445-3451.1989"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0605.000502"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1086\/382594"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1999.60.598"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0118265"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.7589\/0090-3558-30.2.155"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2009.0215"},{"key":"e_1_3_4_15_2","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.2460\/ajvr.1990.51.12.1980","article-title":"Experimental infection of the white-footed mouse with Borrelia burgdorferi","volume":"51","author":"Wright SD","year":"1990","unstructured":"Wright SD, Nielsen SW. 1990. Experimental infection of the white-footed mouse with Borrelia burgdorferi. Am J Vet Res 51:1980\u20131987.","journal-title":"Am J Vet Res"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-020711-075030"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1148526"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri2432"},{"key":"e_1_3_4_19_2","unstructured":"NIAID. 2014. Immune tolerance. National Institute of Allergy and Infectious Diseases Bethesda MD. https:\/\/www.niaid.nih.gov\/research\/immune-tolerance. Accessed 7 January 2021."},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001901"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2017.12.003"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.180197197"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0707454104"},{"key":"e_1_3_4_24_2","doi-asserted-by":"crossref","unstructured":"Fagre A Lewis J Eckley M Zhan S Rocha SM Sexton NR Burke B Geiss B Peersen O Kading R. 2020. SARS-CoV-2 infection neuropathogenesis and transmission among deer mice: implications for reverse zoonosis to New World rodents. bioRxiv doi:10.1101\/2020.08.07.241810.","DOI":"10.1101\/2020.08.07.241810"},{"key":"e_1_3_4_25_2","doi-asserted-by":"crossref","unstructured":"Griffin BD Chan M Tailor N Mendoza EJ Leung A Warner BM Duggan AT Moffat E He S Garnett L. 2020. North American deer mice are susceptible to SARS-CoV-2. bioRxiv doi:10.1101\/2020.07.25.221291.","DOI":"10.1101\/2020.07.25.221291"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02112"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2018.12.007"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/ece3.2645"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.12.003"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.06813"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2016.06.020"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/ilar.39.4.322"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0183070"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-54389-3"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aaw6441"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0231801"},{"key":"e_1_3_4_37_2","first-page":"359","volume-title":"Borrelia: molecular biology, host interaction, and pathogenesis","author":"Barthold SW","year":"2010","unstructured":"Barthold SW, Cadavid D, Phillip MT. 2010. Animal models of borreliosis, p 359\u2013412. In Radolf JD, Samuels DS (ed), Borrelia: molecular biology, host interaction, and pathogenesis. Caister Academic Press, Norfolk, United Kingdom."},{"key":"e_1_3_4_38_2","doi-asserted-by":"publisher","DOI":"10.1006\/rwei.1999.0213"},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.86.1.29"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05836"},{"key":"e_1_3_4_41_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.164.11.5564"},{"key":"e_1_3_4_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/35092578"},{"key":"e_1_3_4_43_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.282.5396.2085"},{"key":"e_1_3_4_44_2","doi-asserted-by":"publisher","DOI":"10.1177\/1753425918771170"},{"key":"e_1_3_4_45_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0510874103"},{"key":"e_1_3_4_46_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.45.1.278-280.1984"},{"key":"e_1_3_4_47_2","doi-asserted-by":"publisher","DOI":"10.3791\/57610"},{"key":"e_1_3_4_48_2","doi-asserted-by":"publisher","DOI":"10.1179\/096805102125000515"},{"key":"e_1_3_4_49_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.113.3.559"},{"key":"e_1_3_4_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.64.3.769-774.1996"},{"key":"e_1_3_4_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/375408a0"},{"key":"e_1_3_4_52_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofu085"},{"key":"e_1_3_4_53_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1504276112"},{"key":"e_1_3_4_54_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02565"},{"key":"e_1_3_4_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2014.06.008"},{"key":"e_1_3_4_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.02.016"},{"key":"e_1_3_4_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2016.07.109"},{"key":"e_1_3_4_58_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI126250"},{"key":"e_1_3_4_59_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri2921"},{"key":"e_1_3_4_60_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.14-253831"},{"key":"e_1_3_4_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.12.001"},{"key":"e_1_3_4_62_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1103320"},{"key":"e_1_3_4_63_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-0816"},{"key":"e_1_3_4_64_2","first-page":"79","article-title":"Human mucus proteinase inhibitor (human MPI). Human seminal inhibitor I (HUSI-I), antileukoprotease (ALP), secretory leukocyte protease inhibitor (SLPI)","volume":"369","author":"Fritz H","year":"1988","unstructured":"Fritz H. 1988. Human mucus proteinase inhibitor (human MPI). Human seminal inhibitor I (HUSI-I), antileukoprotease (ALP), secretory leukocyte protease inhibitor (SLPI). Biol Chem Hoppe Seyler 369(Suppl):79\u201382.","journal-title":"Biol Chem Hoppe Seyler"},{"key":"e_1_3_4_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2016.11.007"},{"key":"e_1_3_4_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/bs.acc.2019.01.002"},{"key":"e_1_3_4_67_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri2448"},{"key":"e_1_3_4_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.07.033"},{"key":"e_1_3_4_69_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-016-1863-0"},{"key":"e_1_3_4_70_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.55.9.2311-2313.1987"},{"key":"e_1_3_4_71_2","first-page":"139","volume-title":"Borrelia: molecular biology, host interaction and pathogenesis","author":"Bergstr\u00f6m S","year":"2010","unstructured":"Bergstr\u00f6m S, Z\u00fcckert WR. 2010. Structure, function and biogenesis of the Borrelia cell envelope, p 139\u2013166. In Radolf JD, Samuels DS (ed), Borrelia: molecular biology, host interaction and pathogenesis. Caister Academic Press, Norwich, United Kingdom."},{"key":"e_1_3_4_72_2","doi-asserted-by":"publisher","DOI":"10.3390\/vetsci3030019"},{"key":"e_1_3_4_73_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00280-17"},{"key":"e_1_3_4_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2013.07.014"},{"key":"e_1_3_4_75_2","volume-title":"Carbonic anhydrase inhibitors","author":"Aslam S","year":"2021","unstructured":"Aslam S, Gupta V. 2021. Carbonic anhydrase inhibitors. In StatPearls [Internet]. StatPearls Publishing, Treasure Island, FL. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557736\/."},{"key":"e_1_3_4_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0149-7634(88)80004-6"},{"key":"e_1_3_4_77_2","first-page":"336","article-title":"Hematologic and serum biochemical values of 4 species of Peromyscus mice and their hybrids","volume":"53","author":"Wiedmeyer CE","year":"2014","unstructured":"Wiedmeyer CE, Crossland JP, Veres M, Dewey MJ, Felder MR, Barlow SC, Vrana PB, Szalai G. 2014. Hematologic and serum biochemical values of 4 species of Peromyscus mice and their hybrids. J Am Assoc Lab Anim Sci 53:336\u2013343.","journal-title":"J Am Assoc Lab Anim Sci"},{"key":"e_1_3_4_78_2","unstructured":"Charles River. 2012. BALB\/C mouse hematology. North American colonies. Charles River Laboratories International Cambridge MA. https:\/\/www.criver.com\/sites\/default\/files\/resources\/BALBcMouseClinicalPathologyData.pdf. Accessed 6 February 2021."},{"key":"e_1_3_4_79_2","first-page":"589","article-title":"Hematology values from clinically healthy Peromyscus leucopus","volume":"30","author":"Wu PJ","year":"1999","unstructured":"Wu PJ, Greeley EH, Hansen LG, Segre M. 1999. Hematology values from clinically healthy Peromyscus leucopus. J Zoo Wildl Med 30:589\u2013590.","journal-title":"J Zoo Wildl Med"},{"key":"e_1_3_4_80_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2015.12.001"},{"key":"e_1_3_4_81_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.4AB1114-543R"},{"key":"e_1_3_4_82_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M203710200"},{"key":"e_1_3_4_83_2","doi-asserted-by":"publisher","DOI":"10.1038\/80489"},{"key":"e_1_3_4_84_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.4A0612-295RR"},{"key":"e_1_3_4_85_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20021824"},{"key":"e_1_3_4_86_2","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/8239258"},{"key":"e_1_3_4_87_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006165"},{"key":"e_1_3_4_88_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002417"},{"key":"e_1_3_4_89_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90085-3"},{"key":"e_1_3_4_90_2","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2004.4.310"},{"key":"e_1_3_4_91_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005346"},{"key":"e_1_3_4_92_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2013.08.013"},{"key":"e_1_3_4_93_2","doi-asserted-by":"publisher","DOI":"10.3390\/cells8020174"},{"key":"e_1_3_4_94_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2008.03.007"},{"key":"e_1_3_4_95_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.08.076"},{"key":"e_1_3_4_96_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0184976"},{"key":"e_1_3_4_97_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00570-19"},{"key":"e_1_3_4_98_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature24661"},{"key":"e_1_3_4_99_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.575586"},{"key":"e_1_3_4_100_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.86.1.39"},{"key":"e_1_3_4_101_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1001952"},{"key":"e_1_3_4_102_2","doi-asserted-by":"publisher","DOI":"10.17226\/25801"},{"key":"e_1_3_4_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2015.04.009"},{"key":"e_1_3_4_104_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2009.09-0208"},{"key":"e_1_3_4_105_2","doi-asserted-by":"publisher","DOI":"10.1089\/dna.2019.4910"},{"key":"e_1_3_4_106_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa1455"},{"key":"e_1_3_4_107_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2377"},{"key":"e_1_3_4_108_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac051437y"},{"key":"e_1_3_4_109_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac026468x"},{"key":"e_1_3_4_110_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003123"},{"key":"e_1_3_4_111_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq054"},{"key":"e_1_3_4_112_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"e_1_3_4_113_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3519"},{"key":"e_1_3_4_114_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp616"},{"key":"e_1_3_4_115_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-14-128"},{"key":"e_1_3_4_116_2","unstructured":"R Core Team. 2013. R: A language and environment for statistical computing. R Foundation for Statistical Computing Vienna Austria. https:\/\/www.r-project.org."},{"key":"e_1_3_4_117_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-9-559"},{"key":"e_1_3_4_118_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12920-017-0253-6"},{"key":"e_1_3_4_119_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"}],"container-title":["mBio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mBio.00588-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mBio.00588-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T00:25:38Z","timestamp":1724804738000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mBio.00588-21"}},"subtitle":[],"editor":[{"given":"Samuel I.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,4,27]]},"references-count":118,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,4,27]]}},"alternative-id":["10.1128\/mBio.00588-21"],"URL":"https:\/\/doi.org\/10.1128\/mbio.00588-21","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.12.13.422519","asserted-by":"object"}]},"ISSN":["2150-7511"],"issn-type":[{"value":"2150-7511","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,27]]},"assertion":[{"value":"2021-03-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00588-21"}}