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Our data show that, in contrast to\n                    <jats:named-content content-type=\"genus-species\">B. pseudomallei<\/jats:named-content>\n                    ,\n                    <jats:named-content content-type=\"genus-species\">B. ubonensis<\/jats:named-content>\n                    \u03b2-lactam resistance is fundamentally different because intrinsic resistance is mediated by an inducible class A \u03b2-lactamase. This includes resistance to carbapenems. Our work demonstrates that studies with near-neighbor species are informative about the diversity of antimicrobial resistance in\n                    <jats:italic>Burkholderia<\/jats:italic>\n                    and can also provide clues about the potential of resistance transfer between bacteria inhabiting the same environment. Knowledge about potential adverse challenges resulting from the horizontal transfer of resistance genes between members of the two complexes enables the design of effective countermeasures.\n                  <\/jats:p>","DOI":"10.1128\/mbio.00592-20","type":"journal-article","created":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T09:41:03Z","timestamp":1586770863000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":13,"title":["Burkholderia ubonensis Meropenem Resistance: Insights into Distinct Properties of Class A \u03b2-Lactamases in Burkholderia cepacia Complex and Burkholderia pseudomallei Complex Bacteria"],"prefix":"10.1128","volume":"11","author":[{"given":"Nawarat","family":"Somprasong","sequence":"first","affiliation":[{"name":"Department of Molecular Genetics &amp; Microbiology, College of Medicine, Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina M.","family":"Hall","sequence":"additional","affiliation":[{"name":"The Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica R.","family":"Webb","sequence":"additional","affiliation":[{"name":"Global and Tropical Heath Division, Menzies School of Health Research, Darwin, Northern Territory, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason W.","family":"Sahl","sequence":"additional","affiliation":[{"name":"The Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Wagner","sequence":"additional","affiliation":[{"name":"The Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0089-5820","authenticated-orcid":false,"given":"Paul","family":"Keim","sequence":"additional","affiliation":[{"name":"The Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart J.","family":"Currie","sequence":"additional","affiliation":[{"name":"Global and Tropical Heath Division, Menzies School of Health Research, Darwin, Northern Territory, Australia"},{"name":"Department of Infectious Diseases, Royal Darwin Hospital, Darwin, Northern Territory, Australia"},{"name":"Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert P.","family":"Schweizer","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics &amp; 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