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The causative agent of fire blight,\n            <jats:named-content content-type=\"genus-species\">Erwinia amylovora<\/jats:named-content>\n            coordinates turning on or off specific virulence-associated traits at the appropriate time during disease development. The development of novel control strategies requires an in-depth understanding of\n            <jats:named-content content-type=\"genus-species\">E. amylovora<\/jats:named-content>\n            regulatory mechanisms, including regulatory control of virulence-associated traits. This study investigates how the small RNA ArcZ regulates motility at the transcriptional level and identifies the transcription factor Lrp as a novel participant in the regulation of several virulence-associated traits. We report that ArcZ and Lrp together affect key virulence-associated traits through integration of transcriptional and posttranscriptional mechanisms. Further understanding of the topology of virulence regulatory networks can uncover weak points that can subsequently be exploited to control\n            <jats:named-content content-type=\"genus-species\">E. amylovora<\/jats:named-content>\n            .\n          <\/jats:p>","DOI":"10.1128\/mbio.00757-19","type":"journal-article","created":{"date-parts":[[2019,5,25]],"date-time":"2019-05-25T10:37:54Z","timestamp":1558780674000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":29,"title":["The Leucine-Responsive Regulatory Protein Lrp Participates in Virulence Regulation Downstream of Small RNA ArcZ in Erwinia amylovora"],"prefix":"10.1128","volume":"10","author":[{"given":"Jeffrey K.","family":"Schachterle","sequence":"first","affiliation":[{"name":"Genetics Graduate Program, Michigan State University, East Lansing, Michigan, USA"},{"name":"Department of Plant, Soil, and Microbial Sciences, Michigan State University, East Lansing, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4078-8368","authenticated-orcid":false,"given":"George W.","family":"Sundin","sequence":"additional","affiliation":[{"name":"Genetics Graduate Program, Michigan State University, East Lansing, Michigan, USA"},{"name":"Department of Plant, Soil, and Microbial Sciences, Michigan State University, East Lansing, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","volume-title":"Fire blight: history, biology, and management","author":"Van der Zwet T","year":"2012","unstructured":"Van der Zwet T, Orolaza-Halbrendt N, Zeller W. 2012. 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