{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:10:17Z","timestamp":1792613417852,"version":"4.5.0"},"reference-count":24,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T00:00:00Z","timestamp":1557187200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T00:00:00Z","timestamp":1561420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["DGE-1650441"],"award-info":[{"award-number":["DGE-1650441"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2019,6,25]]},"abstract":"<jats:p>\n                    Colistin is a last-resort antibiotic that is used to treat severe infections caused by MDR and extensively drug-resistant (XDR) bacteria. The World Health Organization (WHO) has designated colistin as a \u201chighest priority critically important antimicrobial for human medicine\u201d (WHO,\n                    <jats:italic>Critically Important Antimicrobials for Human Medicine<\/jats:italic>\n                    ,\n                    <jats:italic>5th revision<\/jats:italic>\n                    , 2017,\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.who.int\/foodsafety\/publications\/antimicrobials-fifth\/en\/\">https:\/\/www.who.int\/foodsafety\/publications\/antimicrobials-fifth\/en\/<\/jats:ext-link>\n                    ), as it is often one of the only therapies available for treating serious bacterial infections in critically ill patients. Plasmid-borne\n                    <jats:italic>mcr<\/jats:italic>\n                    genes that confer resistance to colistin pose a threat to public health at an international scale, as they can be transmitted via horizontal gene transfer and have the potential to spread globally. Therefore, the establishment of a complete reference of\n                    <jats:italic>mcr<\/jats:italic>\n                    genes that can be used to screen for plasmid-mediated colistin resistance is essential for developing effective control strategies.\n                  <\/jats:p>","DOI":"10.1128\/mbio.00853-19","type":"journal-article","created":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T14:09:19Z","timestamp":1557151759000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":482,"title":["Identification of Novel Mobilized Colistin Resistance Gene\n                    <i>mcr-9<\/i>\n                    in a Multidrug-Resistant, Colistin-Susceptible Salmonella enterica Serotype Typhimurium Isolate"],"prefix":"10.1128","volume":"10","author":[{"given":"Laura M.","family":"Carroll","sequence":"first","affiliation":[{"name":"Department of Food Science, Cornell University, Ithaca, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Gaballa","sequence":"additional","affiliation":[{"name":"Department of Food Science, Cornell University, Ithaca, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Guldimann","sequence":"additional","affiliation":[{"name":"Institute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevieve","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Department of Food Science, Cornell University, Ithaca, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lory O.","family":"Henderson","sequence":"additional","affiliation":[{"name":"Department of Food Science, Cornell University, Ithaca, New York, USA"},{"name":"Department of Microbiology, Cornell University, Ithaca, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Wiedmann","sequence":"additional","affiliation":[{"name":"Department of Food Science, Cornell University, Ithaca, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00424-7"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1612927114"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2016.21.27.30280"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00543-17"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2017.22.31.30589"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx327"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx286"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky111"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41426-018-0124-z"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00140-17"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks261"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02412-14"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-10-421"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01096-17"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkh340"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu033"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2015.053"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20084"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw357"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku316"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00018-18"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.22538"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01950-17"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.849004"}],"container-title":["mBio"],"original-title":[],"contributor":[{"given":"Gregory","family":"Siragusa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"reviewer"}]},{"given":"David","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"reviewer"}]}],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mBio.00853-19","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mBio.00853-19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T21:28:37Z","timestamp":1646688517000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mBio.00853-19"}},"subtitle":[],"editor":[{"given":"Mark 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