{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:44:55Z","timestamp":1787240695538,"version":"build-2736575974"},"reference-count":55,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T00:00:00Z","timestamp":1561420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Margaret Batts Tobin Foundation"},{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI119554"],"award-info":[{"award-number":["R01AI119554"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"HHS | NIH | National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["R01DE023510"],"award-info":[{"award-number":["R01DE023510"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2019,6,25]]},"abstract":"<jats:p>\n                    Microbial communities have a great impact in health and disease.\n                    <jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>\n                    interacts with multiple microorganisms in the oral cavity, frequently forming polymicrobial biofilms. We report on the synergistic interactions between\n                    <jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>\n                    and the Gram-positive bacterium\n                    <jats:named-content content-type=\"genus-species\">S. gordonii<\/jats:named-content>\n                    , for which we have examined the different contributions of adhesive interactions, filamentation, and the extracellular matrix to the formation of dual-species biofilms. Our results demonstrate that growth in the presence of the bacterium can restore the biofilm-forming ability of different\n                    <jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>\n                    mutant strains with defects in adhesion and filamentation. The mixed-species biofilms also show high levels of resistance to antibacterial and antifungal antibiotics, and our results indicate that the fungal biofilm matrix protects bacterial cells within these mixed-species biofilms. Our observations add to a growing body of evidence indicating a high level of complexity in the reciprocal interactions and consortial behavior of fungal\/bacterial biofilms.\n                  <\/jats:p>","DOI":"10.1128\/mbio.01179-19","type":"journal-article","created":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T07:01:43Z","timestamp":1560754903000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":51,"title":["Contributions of Candida albicans Dimorphism, Adhesive Interactions, and Extracellular Matrix to the Formation of Dual-Species Biofilms with Streptococcus gordonii"],"prefix":"10.1128","volume":"10","author":[{"given":"Daniel","family":"Montelongo-Jauregui","sequence":"first","affiliation":[{"name":"Department of Biology, The University of Texas at San Antonio, San Antonio, Texas, USA"},{"name":"South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, 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