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A prevailing theory is that\n                    <jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>\n                    evolves primarily through the gradual buildup of mitotic mutations, and a pressing issue is whether sexual or parasexual processes also operate within natural populations. Here, we establish that the\n                    <jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>\n                    genome evolves by a combination of localized mutation and both short-tract and long-tract loss-of-heterozygosity (LOH) events within the sequenced isolates. Mutations are more prevalent within noncoding and heterozygous regions and LOH increases towards chromosome ends. Furthermore, we provide evidence for genetic exchange between isolates, establishing that sexual or parasexual processes have contributed to the diversity of both nuclear and mitochondrial genomes.\n                  <\/jats:p>","DOI":"10.1128\/mbio.01205-18","type":"journal-article","created":{"date-parts":[[2018,9,18]],"date-time":"2018-09-18T01:27:37Z","timestamp":1537234057000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":65,"title":["The Genome of the Human Pathogen\n                    <i>Candida albicans<\/i>\n                    Is Shaped by Mutation and Cryptic Sexual Recombination"],"prefix":"10.1128","volume":"9","author":[{"given":"Joshua M.","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island, USA"},{"name":"Department of Microbiology, The Ohio State University, Columbus, Ohio, 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