{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T13:54:18Z","timestamp":1791554058907,"version":"4.3.4"},"reference-count":7,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000057","name":"HHS | NIH | National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["P20GM113131"],"award-info":[{"award-number":["P20GM113131"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2024,8,14]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Intracellular infection by a pathogen induces significant rewiring of host cell signaling and biological processes. Understanding how an intracellular pathogen such as\n                      <jats:italic toggle=\"yes\">Toxoplasma gondii<\/jats:italic>\n                      modulates host cell metabolism with single-cell resolution has been challenged by the variability of infection within cultures and difficulties in separating host and parasite metabolic processes. A new study from Gallego-Lopez and colleagues (G. M. Gallego-L\u00f3pez, E. C. Guzman, D. E. Desa, L. J. Knoll, M. C. Skala, mBio e00727-24, 2024,\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/doi.org\/10.1128\/mbio.00727-24\" xlink:type=\"simple\">https:\/\/doi.org\/10.1128\/mbio.00727-24<\/jats:ext-link>\n                      ) applies a quantitative imaging approach to evaluate the host cell metabolism during intracellular infection with\n                      <jats:italic toggle=\"yes\">Toxoplasma<\/jats:italic>\n                      . This study provides important insights into host metabolic responses to\n                      <jats:italic toggle=\"yes\">Toxoplasma<\/jats:italic>\n                      infection and offers a valuable tool to dissect the mechanisms underlying parasite infection and pathophysiology.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/mbio.01211-24","type":"journal-article","created":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T09:00:43Z","timestamp":1720774843000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["Seeing the unseen: illuminating\n                    <i>Toxoplasma gondii\u2019s<\/i>\n                    metabolic manipulation"],"prefix":"10.1128","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4989-8918","authenticated-orcid":true,"given":"Diego","family":"Huet","sequence":"first","affiliation":[{"name":"Center for Tropical and Emerging Global Diseases, University of Georgia","place":["Athens, USA"]},{"name":"Department of Pharmaceutical and Biomedical Sciences, University of Georgia","place":["Athens, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1233-1088","authenticated-orcid":true,"given":"Victoria","family":"Jeffers","sequence":"additional","affiliation":[{"name":"Department of Molecular, Cellular and Biomedical Sciences, University of New Hampshire","place":["Durham, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.00727-24"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.25.7.071203"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-bioeng-071516-044730"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-018-0255-3"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-02-0666"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2022.10.001"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.798549"}],"container-title":["mBio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mbio.01211-24","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mbio.01211-24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T13:38:16Z","timestamp":1791553096000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mbio.01211-24"}},"subtitle":[],"editor":[{"given":"Anita A.","family":"Koshy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2024,8,14]]},"references-count":7,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8,14]]}},"alternative-id":["10.1128\/mbio.01211-24"],"URL":"https:\/\/doi.org\/10.1128\/mbio.01211-24","relation":{},"ISSN":["2150-7511"],"issn-type":[{"value":"2150-7511","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,14]]},"assertion":[{"value":"2024-07-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01211-24"}}