{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T10:25:36Z","timestamp":1769855136102,"version":"3.49.0"},"reference-count":11,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T00:00:00Z","timestamp":1721174400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T00:00:00Z","timestamp":1721174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Science and Technology Department of Sichuan Province","award":["2023JDKP0037"],"award-info":[{"award-number":["2023JDKP0037"]}]},{"name":"MOST | National Key Research and Development Program of China","award":["2023YFC2412900"],"award-info":[{"award-number":["2023YFC2412900"]}]},{"name":"Institutional Research Fund from Sichuan University","award":["2023SCUH0018"],"award-info":[{"award-number":["2023SCUH0018"]}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2024,7,17]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:sec>\n            <jats:title\/>\n            <jats:p>\n              A recent study published in\n              <jats:italic>mBio<\/jats:italic>\n              by Cao et al. demonstrated that the helminth\n              <jats:italic>Trichinella sprialis<\/jats:italic>\n              (Ts) alleviates COVID-19-related cytokine storms in an IL-9-dependent way (Z. Cao, J. Wang, X. Liu, Y. Liu, et al., mBio 15:e00905-24, 2024,\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/doi.org\/10.1128\/mbio.00905-24\" xlink:type=\"simple\">https:\/\/doi.org\/10.1128\/mbio.00905-24<\/jats:ext-link>\n              ). A cytokine storm is a severe immune response characterized by the overproduction of proinflammatory cytokines, such as TNF-\u03b1 and IFN-\u03b3, leading to tissue damage and mortality in COVID-19 patients. This study indicated that IL-9 is crucial in protecting against cytokine storm syndromes associated with SARS-CoV-2 infection and proposed that anti-inflammatory molecules from Ts excretory\/secretory (TsES) products could be a novel source for treating such illnesses.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1128\/mbio.01229-24","type":"journal-article","created":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T13:01:01Z","timestamp":1718888461000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":4,"title":["IL-9 plays a critical role in helminth-induced protection against COVID-19-related cytokine storms"],"prefix":"10.1128","volume":"15","author":[{"given":"ChunXiao","family":"Xiang","sequence":"first","affiliation":[{"name":"Medical Simulation Centre, West China Second University Hospital, Sichuan University, Chengdu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Zhong","sequence":"additional","affiliation":[{"name":"University\/Trauma Center, West China Hospital, Sichuan University, Chengdu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8851-9842","authenticated-orcid":false,"given":"Huiqing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10122145"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.27588"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-017-0639-8"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.11.025"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-021-01091-0"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2021.102845"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70771-6"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2021.101054"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.adf8161"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2012.06.003"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.00905-24"}],"container-title":["mBio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mbio.01229-24","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mbio.01229-24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T13:02:43Z","timestamp":1721221363000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mbio.01229-24"}},"subtitle":[],"editor":[{"given":"Chunfu","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2024,7,17]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7,17]]}},"alternative-id":["10.1128\/mbio.01229-24"],"URL":"https:\/\/doi.org\/10.1128\/mbio.01229-24","relation":{},"ISSN":["2150-7511"],"issn-type":[{"value":"2150-7511","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,17]]},"assertion":[{"value":"2024-06-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01229-24"}}