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This study used recently developed genetic tools to determine the regulon for one of the key transcription factors encoded by\n            <jats:italic>Chlamydia<\/jats:italic>\n            , sigma 54. Surrogate and computational analyses provide additional support for the hypothesis that sigma 54 plays a key role in controlling the expression of many components critical to converting and enabling the infectious capability of\n            <jats:italic>Chlamydia<\/jats:italic>\n            . 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