{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T04:42:43Z","timestamp":1790484163946,"version":"4.1.0"},"reference-count":59,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T00:00:00Z","timestamp":1666742400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T00:00:00Z","timestamp":1666742400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01 AI153332"],"award-info":[{"award-number":["R01 AI153332"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"HHS | NIH | National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS116716"],"award-info":[{"award-number":["R01NS116716"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["5T32AI052066-18"],"award-info":[{"award-number":["5T32AI052066-18"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI164674-01"],"award-info":[{"award-number":["AI164674-01"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2022,10,26]]},"abstract":"<jats:p>Group B<jats:named-content content-type=\"genus-species\">Streptococcus<\/jats:named-content>(GBS) asymptomatically colonizes the female reproductive tract (FRT) of up to one third of women, but GBS carriage can lead to adverse pregnancy outcomes, including premature rupture of membranes, preterm labor, and chorioamnionitis. GBS colonization during pregnancy is also the largest predisposing factor for neonatal GBS disease, including pneumonia, sepsis, and meningitis.<\/jats:p>","DOI":"10.1128\/mbio.01781-22","type":"journal-article","created":{"date-parts":[[2022,9,7]],"date-time":"2022-09-07T12:01:33Z","timestamp":1662552093000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":13,"title":["The Group B Streptococcal Adhesin BspC Interacts with Host Cytokeratin 19 To Promote Colonization of the Female Reproductive Tract"],"prefix":"10.1128","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2864-6212","authenticated-orcid":false,"given":"Haider S.","family":"Manzer","sequence":"first","affiliation":[{"name":"University of Colorado Anschutz Medical Campus, Department of Immunology and Microbiology, Aurora, Colorado, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dustin T.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"University of Colorado Anschutz Medical Campus, Department of Immunology and Microbiology, Aurora, Colorado, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8375-0178","authenticated-orcid":true,"given":"Joo Youn","family":"Park","sequence":"additional","affiliation":[{"name":"Mississippi State University, Department of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nogi","family":"Park","sequence":"additional","affiliation":[{"name":"Mississippi State University, Department of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9280-9680","authenticated-orcid":true,"given":"Keun Seok","family":"Seo","sequence":"additional","affiliation":[{"name":"Mississippi State University, Department of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin A.","family":"Thornton","sequence":"additional","affiliation":[{"name":"Mississippi State University, Department of Biological Sciences, Mississippi State, Mississippi, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3813-4410","authenticated-orcid":true,"given":"Angela H.","family":"Nobbs","sequence":"additional","affiliation":[{"name":"University of Bristol, Bristol Dental School, Bristol, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4232-6837","authenticated-orcid":true,"given":"Kelly S.","family":"Doran","sequence":"additional","affiliation":[{"name":"University of Colorado Anschutz Medical Campus, Department of Immunology and Microbiology, Aurora, Colorado, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-200010000-00003"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.JPN.0000333925.30328.fd"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix664"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix585"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.14734\/PN.2018.29.4.147"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1086\/314756"},{"key":"e_1_3_2_8_2","first-page":"816","article-title":"Peripartum infection associated with vaginal Group B streptococcal colonization","volume":"84","author":"Yancey MK","year":"1994","unstructured":"Yancey MK, Duff P, Clark P, Kurtzer T, Frentzen BH, Kubilis P. 1994. Peripartum infection associated with vaginal Group B streptococcal colonization. Obstet Gynecol 84:816\u2013819.","journal-title":"Obstet Gynecol"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.08.040"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00094-11"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu151"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.00039-22"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00762-17"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.602305"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2010.07212.x"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1010397"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007848"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.3390\/cells5020018"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00340-21"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00669-17"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.726562"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1086\/517408"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2015.23"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy341"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02321-19"},{"key":"e_1_3_2_26_2","first-page":"54708","article-title":"A murine model of group B Streptococcus vaginal colonization","volume":"117","author":"Patras KA","year":"2016","unstructured":"Patras KA, Doran KS. 2016. A murine model of group B Streptococcus vaginal colonization. J Vis Exp 117:54708.","journal-title":"J Vis Exp"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00649"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1017\/S2040174418001083"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2014.46"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.99.3.595"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2009.06796.x"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2017.00081"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.626663"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/febs.15158"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.060855-0"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10858-016-0017-1"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-62115-7"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1313491110"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1310493110"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI38214"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1159\/000293334"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.3892\/or.4.1.79"},{"key":"e_1_3_2_43_2","first-page":"599","article-title":"Cytokeratins of normal epithelia and some neoplasms of the female genital tract","volume":"49","author":"Moll R","year":"1983","unstructured":"Moll R, Levy R, Czernobilsky B, Hohlweg-Majert P, Dallenbach-Hellweg G, Franke WW. 1983. Cytokeratins of normal epithelia and some neoplasms of the female genital tract. Lab Invest 49:599\u2013610.","journal-title":"Lab Invest"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19051423"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2119463119"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-51195-9"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2017.7102"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI97043"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiaa280"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0912293107"},{"key":"e_1_3_2_51_2","unstructured":"U.S. Food and Drug Administration. 2012. Kyprolis (carfilzomib) for injection for intravenous use. U.S. Food and Drug Administration Washington DC."},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2019-127350"},{"key":"e_1_3_2_53_2","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1155\/S1064744998000131","article-title":"Female genital tract bacterial coisolates with Candida albicans in patients without clinical vaginitis","volume":"6","author":"Monif GR","year":"1998","unstructured":"Monif GR, Carson HJ. 1998. Female genital tract bacterial coisolates with Candida albicans in patients without clinical vaginitis. Infect Dis Obstet Gynecol 6:52\u201356.","journal-title":"Infect Dis Obstet Gynecol"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10123-002-0064-1"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)80028-8"},{"key":"e_1_3_2_56_2","volume-title":"Guide for the care and use of laboratory animals","author":"National Research Council","year":"2011","unstructured":"National Research Council. 2011. Guide for the care and use of laboratory animals, 8th ed. National Academies Press, Washington, DC.","edition":"8"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod57.4.847"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI23829"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002964"},{"key":"e_1_3_2_60_2","unstructured":"DeLano WL. 2002. The PyMOL molecular graphics system. http:\/\/www.pymol.org."}],"container-title":["mBio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mbio.01781-22","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mbio.01781-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,3]],"date-time":"2024-10-03T10:59:54Z","timestamp":1727953194000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mbio.01781-22"}},"subtitle":[],"editor":[{"given":"Nancy E.","family":"Freitag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,10,26]]},"references-count":59,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,10,26]]}},"alternative-id":["10.1128\/mbio.01781-22"],"URL":"https:\/\/doi.org\/10.1128\/mbio.01781-22","relation":{},"ISSN":["2150-7511"],"issn-type":[{"value":"2150-7511","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,26]]},"assertion":[{"value":"2022-06-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01781-22"}}