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There is increasing evidence that indicates that resident bacteria play a role; some commensal species can eradicate\n                    <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n                    from the nasal cavity. Among these,\n                    <jats:named-content content-type=\"genus-species\">Corynebacterium pseudodiphtheriticum<\/jats:named-content>\n                    can eliminate\n                    <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n                    from the human nose. We sought to understand this phenomenon at a molecular level and found that\n                    <jats:named-content content-type=\"genus-species\">C. pseudodiphtheriticum<\/jats:named-content>\n                    produces a factor(s) that specifically kills\n                    <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n                    . While resistant\n                    <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n                    isolates were recovered at a low frequency, resistance came at the cost of attenuated virulence in these strains. Molecular dissection of the specific strategies used by\n                    <jats:named-content content-type=\"genus-species\">C. pseudodiphtheriticum<\/jats:named-content>\n                    to kill\n                    <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n                    could lead to the development of novel treatments or therapies. Furthermore, commensal competition that requires virulence components of the competitor may represent an exciting and unexplored possibility for development of novel antimicrobial compounds.\n                  <\/jats:p>","DOI":"10.1128\/mbio.02491-18","type":"journal-article","created":{"date-parts":[[2019,1,7]],"date-time":"2019-01-07T17:31:10Z","timestamp":1546882270000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":97,"title":["Corynebacterium pseudodiphtheriticum Exploits Staphylococcus aureus Virulence Components in a Novel Polymicrobial Defense Strategy"],"prefix":"10.1128","volume":"10","author":[{"given":"Britney L.","family":"Hardy","sequence":"first","affiliation":[{"name":"F. Edward H\u00e9bert School of Medicine, Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seth W.","family":"Dickey","sequence":"additional","affiliation":[{"name":"Pathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger D.","family":"Plaut","sequence":"additional","affiliation":[{"name":"Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel P.","family":"Riggins","sequence":"additional","affiliation":[{"name":"Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Stibitz","sequence":"additional","affiliation":[{"name":"Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Otto","sequence":"additional","affiliation":[{"name":"Pathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7095-5177","authenticated-orcid":false,"given":"D. 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