{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:02:35Z","timestamp":1791460955282,"version":"4.3.4"},"reference-count":108,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"MOST | National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82372280"],"award-info":[{"award-number":["82372280"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100012131","name":"Department of Science and Technology of Liaoning Province","doi-asserted-by":"crossref","award":["2022-MS-239"],"award-info":[{"award-number":["2022-MS-239"]}],"id":[{"id":"10.13039\/501100012131","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"crossref","award":["R01 AI150533"],"award-info":[{"award-number":["R01 AI150533"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"crossref","award":["R01AI128940"],"award-info":[{"award-number":["R01AI128940"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"crossref","award":["U19AI089672"],"award-info":[{"award-number":["U19AI089672"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2025,1,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:sec>\n            <jats:title\/>\n            <jats:p>\n              The inner membrane complex (IMC), a double-membrane organelle underneath the plasma membrane in apicomplexan parasites, plays a significant role in motility and invasion and confers shape to the cell. We characterized the function of PbIMC1g, a component of the IMC1 family member in\n              <jats:italic>Plasmodium berghei<\/jats:italic>\n              . PbIMC1g is recruited to the IMC in late schizonts, activated gametocytes, and ookinetes. Pairwise yeast two-hybrid assays demonstrate that PbIMC1g interacts with IMC1c, a component of the PHIL1 complex, and the core sub-repeat motif \u201cEKI(V)V(I)EVP\u201d in PbIMC1g is essential for this interaction. Localization of PbIMC1g to the IMC was dependent on its IMCp domain, while its C-terminus and palmitoylation sites were required for the full efficiency of proper IMC targeting. PbIMC1g is required for asexual stage development, and its conditional knockdown resulted in a defect in schizogony. Additionally, PbIMC1g was also important for male gametogenesis and ookinete development. As an IMC component that assists in anchoring the glideosome to the subpellicular network, PbIMC1g was also involved in ookinete motility and mosquito midgut invasion. IMC1g from the human parasite\n              <jats:italic>Plasmodium vivax<\/jats:italic>\n              could functionally replace PbIMC1g in\n              <jats:italic>P. berghei<\/jats:italic>\n              , confirming the evolutionary conservation of IMC1g proteins in\n              <jats:italic>Plasmodium<\/jats:italic>\n              spp. Together, this work reveals an essential role of IMC1g in the parasite life cycle and suggests that IMC1 family members likely contribute to parasite gliding and invasion.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>IMPORTANCE<\/jats:title>\n            <jats:p>\n              The malaria parasite\u2019s inner membrane complex is critical to maintain its structural integrity and motility. Here, we identified the function of the IMC1g protein, a member of the IMC1 family, in invasive and proliferative stages of\n              <jats:italic>P. berghei<\/jats:italic>\n              . We found that the IMCp domain of PbIMC1g is critical for proper IMC targeting, and PbIMC1g interacts with PbIMC1c. Conditional knockdown of PbIMC1g expression affects schizogony, gametogenesis, and ookinete conversion. PbIMC1g interacts with IMC1c to firmly anchor the glideosome to the subpellicular network. Additionally, we confirmed that IMC1g is functionally conserved in\n              <jats:italic>Plasmodium<\/jats:italic>\n              spp. These data reveal the function of IMC1g protein in anchoring the glideosome, providing further insight into the mechanism of the glideosome function.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1128\/mbio.02652-24","type":"journal-article","created":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T14:00:48Z","timestamp":1732284048000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":5,"title":["An inner membrane complex protein IMC1g in\n            <i>Plasmodium berghei<\/i>\n            is involved in asexual stage schizogony and parasite transmission"],"prefix":"10.1128","volume":"16","author":[{"given":"Yinjie","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences, China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shitong","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, the First Hospital of China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"He","sequence":"additional","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences, China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawei","family":"He","sequence":"additional","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences, China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences, China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sicong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences, China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lumeng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences, China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liying","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences, China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3145-6409","authenticated-orcid":false,"given":"Yonghui","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, the First Hospital of China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8338-1974","authenticated-orcid":true,"given":"Liwang","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Morsani College of Medicine, University of South Florida","place":["Tampa, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5315-1636","authenticated-orcid":true,"given":"Yaming","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences, China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9064-586X","authenticated-orcid":true,"given":"Xiaotong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Immunology, College of Basic Medical Sciences, China Medical University","place":["Shenyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_5_2_2","unstructured":"Organization WHO. 2023. World malaria report"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/415673a"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2015.08.002"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12604"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.091208.073403"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3519"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2015.02.008"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2010.09.002"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0166-6851(01)00289-4"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.036772"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mss081"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.099002"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.110.1.35"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0955-0674(96)80047-0"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.01-06-0309"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1009750"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006659"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-15781-z"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.01507-23"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-08318-7"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msn070"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1103717"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200406068"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-014-4226-9"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2016.09.004"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M801302200"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.187195"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041409"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2019.00266"},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2018.12.239"},{"key":"e_1_3_5_32_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-016-1932-4"},{"key":"e_1_3_5_33_2","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2021109070"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.598094"},{"key":"e_1_3_5_35_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.77447"},{"key":"e_1_3_5_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/2211-5463.12564"},{"key":"e_1_3_5_37_2","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M800270-JLR200"},{"key":"e_1_3_5_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2012.03.006"},{"key":"e_1_3_5_39_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-014-4093-4"},{"key":"e_1_3_5_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2010.07.009"},{"key":"e_1_3_5_41_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1018449108"},{"key":"e_1_3_5_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2017.86"},{"key":"e_1_3_5_43_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msq321"},{"key":"e_1_3_5_44_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-12-587"},{"key":"e_1_3_5_45_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep40655"},{"key":"e_1_3_5_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.02.075"},{"key":"e_1_3_5_47_2","doi-asserted-by":"publisher","DOI":"10.1385\/1-59259-762-9:297"},{"key":"e_1_3_5_48_2","doi-asserted-by":"publisher","DOI":"10.1006\/jsbi.2001.4396"},{"key":"e_1_3_5_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2004.08.002"},{"key":"e_1_3_5_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00244-10"},{"key":"e_1_3_5_51_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200311137"},{"key":"e_1_3_5_52_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1001094"},{"key":"e_1_3_5_53_2","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2019104168"},{"key":"e_1_3_5_54_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.13112"},{"key":"e_1_3_5_55_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.03622-20"},{"key":"e_1_3_5_56_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3000475"},{"key":"e_1_3_5_57_2","doi-asserted-by":"publisher","DOI":"10.1126\/stke.3592006re14"},{"key":"e_1_3_5_58_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2084"},{"key":"e_1_3_5_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2013.02.022"},{"key":"e_1_3_5_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2012.05.002"},{"key":"e_1_3_5_61_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/21.9.2149"},{"key":"e_1_3_5_62_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1074553"},{"key":"e_1_3_5_63_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0023977"},{"key":"e_1_3_5_64_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00114-06"},{"key":"e_1_3_5_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2015.09.006"},{"key":"e_1_3_5_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2017.02.003"},{"key":"e_1_3_5_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2012.06.005"},{"key":"e_1_3_5_68_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003162"},{"key":"e_1_3_5_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2013.09.004"},{"key":"e_1_3_5_70_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.9b00321"},{"key":"e_1_3_5_71_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12599"},{"key":"e_1_3_5_72_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-10214-z"},{"key":"e_1_3_5_73_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.06.030"},{"key":"e_1_3_5_74_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aap7847"},{"key":"e_1_3_5_75_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-micro-091014-104100"},{"key":"e_1_3_5_76_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.611801"},{"key":"e_1_3_5_77_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007946"},{"key":"e_1_3_5_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2006.10.003"},{"key":"e_1_3_5_79_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2010.07442.x"},{"key":"e_1_3_5_80_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.13121"},{"key":"e_1_3_5_81_2","doi-asserted-by":"publisher","DOI":"10.26508\/lsa.201900488"},{"key":"e_1_3_5_82_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.embor.7400404"},{"key":"e_1_3_5_83_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2005.04793.x"},{"key":"e_1_3_5_84_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/19.22.6030"},{"key":"e_1_3_5_85_2","doi-asserted-by":"publisher","DOI":"10.1006\/expr.1998.4388"},{"key":"e_1_3_5_86_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3001704"},{"key":"e_1_3_5_87_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0169-4758(00)01664-1"},{"key":"e_1_3_5_88_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.00194"},{"key":"e_1_3_5_89_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msab120"},{"key":"e_1_3_5_90_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku316"},{"key":"e_1_3_5_91_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msy096"},{"key":"e_1_3_5_92_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz357"},{"key":"e_1_3_5_93_2","doi-asserted-by":"publisher","DOI":"10.1093\/protein\/gzn039"},{"key":"e_1_3_5_94_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-017-2107-2"},{"key":"e_1_3_5_95_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-016-1459-8"},{"key":"e_1_3_5_96_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4223"},{"key":"e_1_3_5_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2019.03.007"},{"key":"e_1_3_5_98_2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00150-22"},{"key":"e_1_3_5_99_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.53"},{"key":"e_1_3_5_100_2","doi-asserted-by":"publisher","DOI":"10.1006\/expr.1998.4203"},{"key":"e_1_3_5_101_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2004.05.009"},{"key":"e_1_3_5_102_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2019"},{"key":"e_1_3_5_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2012.12.006"},{"key":"e_1_3_5_104_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000599"},{"key":"e_1_3_5_105_2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01434-23"},{"key":"e_1_3_5_106_2","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.01897-22"},{"key":"e_1_3_5_107_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3317"},{"key":"e_1_3_5_108_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.209601.116"},{"key":"e_1_3_5_109_2","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2010-11-2-r14"}],"container-title":["mBio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mbio.02652-24","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mbio.02652-24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T14:03:06Z","timestamp":1736344986000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mbio.02652-24"}},"subtitle":[],"editor":[{"given":"Dominique","family":"Soldati-Favre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,1,8]]},"references-count":108,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1,8]]}},"alternative-id":["10.1128\/mbio.02652-24"],"URL":"https:\/\/doi.org\/10.1128\/mbio.02652-24","relation":{},"ISSN":["2150-7511"],"issn-type":[{"value":"2150-7511","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,8]]},"assertion":[{"value":"2024-08-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e02652-24"}}