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Understanding key metabolic processes in malaria parasites is critical to the development of new drugs to combat this major infectious disease. The\n            <jats:italic>Plasmodium<\/jats:italic>\n            glycolytic pathway is essential to the malaria parasite, providing energy for growth and replication and supplying important biomolecules for other essential\n            <jats:italic>Plasmodium<\/jats:italic>\n            anabolic pathways. Despite this overreliance on glycolysis, no current drugs target glycolysis, and there is a paucity of information on critical glycolysis targets. Our work addresses this unmet need, providing new mechanistic insights into this key pathway.\n          <\/jats:p>","DOI":"10.1128\/mbio.02842-20","type":"journal-article","created":{"date-parts":[[2020,12,7]],"date-time":"2020-12-07T16:59:06Z","timestamp":1607360346000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides"],"prefix":"10.1128","volume":"11","author":[{"given":"Gillian M.","family":"Fisher","sequence":"first","affiliation":[{"name":"Griffith Institute for Drug Discovery, Griffith University, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon A.","family":"Cobbold","sequence":"additional","affiliation":[{"name":"University of Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Jezewski","sequence":"additional","affiliation":[{"name":"Washington School of Medicine, St. Louis, Missouri, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1911-6842","authenticated-orcid":false,"given":"Emma F.","family":"Carpenter","sequence":"additional","affiliation":[{"name":"Wellcome Sanger Institute, Cambridge, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Arnold","sequence":"additional","affiliation":[{"name":"Griffith Institute for Drug Discovery, Griffith University, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie N.","family":"Cowell","sequence":"additional","affiliation":[{"name":"University of California, San Diego, San Diego, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1711-0815","authenticated-orcid":false,"given":"Erick T.","family":"Tjhin","sequence":"additional","affiliation":[{"name":"The Australian National University, Canberra, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3345-8440","authenticated-orcid":false,"given":"Kevin J.","family":"Saliba","sequence":"additional","affiliation":[{"name":"The Australian National University, Canberra, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7011-3850","authenticated-orcid":false,"given":"Tina S.","family":"Skinner-Adams","sequence":"additional","affiliation":[{"name":"Griffith Institute for Drug Discovery, Griffith University, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus C. 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