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Here, we report a novel acid tolerance mechanism where\n            <jats:sc>l-<\/jats:sc>\n            serine is deaminated to pyruvate and ammonia, promoting survival of\n            <jats:named-content content-type=\"genus-species\">E. coli<\/jats:named-content>\n            under acidic conditions. This study is important as it provides evidence of the use of\n            <jats:sc>l-<\/jats:sc>\n            serine as an acid response strategy, not previously reported for\n            <jats:named-content content-type=\"genus-species\">E. coli<\/jats:named-content>\n            .\n          <\/jats:p>","DOI":"10.1128\/mbio.02963-22","type":"journal-article","created":{"date-parts":[[2022,12,5]],"date-time":"2022-12-05T14:04:16Z","timestamp":1670249056000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":44,"title":["Serine Deamination Is a New Acid Tolerance Mechanism Observed in Uropathogenic Escherichia coli"],"prefix":"10.1128","volume":"13","author":[{"given":"Michelle A.","family":"Wiebe","sequence":"first","affiliation":[{"name":"Vanderbilt University, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Brannon","sequence":"additional","affiliation":[{"name":"Department of Pathology, Microbiology &amp; Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley D.","family":"Steiner","sequence":"additional","affiliation":[{"name":"Vanderbilt University, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adebisi","family":"Bamidele","sequence":"additional","affiliation":[{"name":"Vanderbilt University, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra C.","family":"Schrimpe-Rutledge","sequence":"additional","affiliation":[{"name":"Vanderbilt University, Nashville, Tennessee, USA"},{"name":"Center for Innovative Technologies, Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona G.","family":"Codreanu","sequence":"additional","affiliation":[{"name":"Vanderbilt University, Nashville, Tennessee, USA"},{"name":"Center for Innovative Technologies, Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacy D.","family":"Sherrod","sequence":"additional","affiliation":[{"name":"Vanderbilt University, Nashville, Tennessee, USA"},{"name":"Center for Innovative Technologies, Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"McLean","sequence":"additional","affiliation":[{"name":"Vanderbilt University, Nashville, Tennessee, USA"},{"name":"Center for Innovative Technologies, Department of Chemistry, Vanderbilt University, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4249-8997","authenticated-orcid":true,"given":"Maria","family":"Hadjifrangiskou","sequence":"additional","affiliation":[{"name":"Department of Pathology, Microbiology &amp; Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA"},{"name":"Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee, USA"},{"name":"Institute for Infection, Immunology &amp; Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6976.12076"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)65154-1"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1021"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.118.251413"},{"key":"e_1_3_2_6_2","first-page":"1153","article-title":"Urinalysis: a comprehensive review","volume":"71","author":"Simerville JA","year":"2005","unstructured":"Simerville JA, Maxted WC, Pahira JJ. 2005. 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