{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T09:00:35Z","timestamp":1785402035078,"version":"3.56.0"},"reference-count":38,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2025,11,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Leishmaniasis is a disease caused by\n                      <jats:italic toggle=\"yes\">Leishmania<\/jats:italic>\n                      parasites, transmitted by insects, that occurs worldwide. The parasite and parasite-infected cells release extracellular vesicles (EVs), which are involved in numerous biological processes. EVs secreted by\n                      <jats:italic toggle=\"yes\">Leishmania<\/jats:italic>\n                      modulate the host cell and, in turn, the immune response. In this review, we focused on two particular EV-related topics: (i) EVs as carriers of\n                      <jats:italic toggle=\"yes\">Leishmania<\/jats:italic>\n                      virulence factors and implications in parasite biology, and (ii) the effects of\n                      <jats:italic toggle=\"yes\">Leishmania<\/jats:italic>\n                      -derived EVs on the host\u2019s immune response.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/mbio.03239-24","type":"journal-article","created":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T13:00:36Z","timestamp":1758546036000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":1,"title":["mGem: Extracellular vesicles in\n                    <i>Leishmania<\/i>\n                    \u2014secret messengers driving infection and disease"],"prefix":"10.1128","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6329-6449","authenticated-orcid":false,"given":"Patricia","family":"Xander","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02k5swt12","id-type":"ROR","asserted-by":"publisher"}],"name":"Departamento de Ci\u00eancias Farmac\u00eauticas, Instituto de Ci\u00eancias Ambientais Qu\u00edmicas e Farmac\u00eauticas, UNIFESP","place":["Diadema, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7868-5164","authenticated-orcid":true,"given":"Camila I.","family":"de Oliveira","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04jhswv08","id-type":"ROR","asserted-by":"publisher"}],"name":"Instituto Gon\u00e7alo Muniz, FIOCRUZ","place":["Salvador, Brazil"]},{"id":[{"id":"https:\/\/ror.org\/05fbb1126","id-type":"ROR","asserted-by":"publisher"}],"name":"Instituto Nacional de Ci\u00eancia e Tecnologia em Doen\u00e7as 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