{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T01:27:47Z","timestamp":1788830867590,"version":"build-2803163510"},"reference-count":24,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T00:00:00Z","timestamp":1614038400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["CA010815"],"award-info":[{"award-number":["CA010815"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["S10 OD023586"],"award-info":[{"award-number":["S10 OD023586"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R21 AI143385"],"award-info":[{"award-number":["R21 AI143385"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R21 AI129636"],"award-info":[{"award-number":["R21 AI129636"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["P30 AI 045008"],"award-info":[{"award-number":["P30 AI 045008"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001117","name":"amfAR, The Foundation for AIDS Research","doi-asserted-by":"publisher","award":["109840-65-RGRL"],"award-info":[{"award-number":["109840-65-RGRL"]}],"id":[{"id":"10.13039\/100001117","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R01 DK123733"],"award-info":[{"award-number":["R01 DK123733"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"HHS | NIH | National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS117458"],"award-info":[{"award-number":["R01NS117458"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"HHS | NIH | National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R21 NS106970"],"award-info":[{"award-number":["R21 NS106970"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"HHS | NIH | National Institute on Aging","doi-asserted-by":"publisher","award":["R01 AG062383"],"award-info":[{"award-number":["R01 AG062383"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001340","name":"W. W. Smith Charitable Trust","doi-asserted-by":"publisher","award":["A1901"],"award-info":[{"award-number":["A1901"]}],"id":[{"id":"10.13039\/100001340","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Robert I. Jacobs Fund of the Philadelphia Foundation-the Herbert Kean, M.D., Family Professorship","award":["U01AI110434"],"award-info":[{"award-number":["U01AI110434"]}]},{"name":"Robert I. Jacobs Fund of the Philadelphia Foundation-the Herbert Kean, M.D., Family Professorship","award":["UM1AI126620"],"award-info":[{"award-number":["UM1AI126620"]}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2021,2,23]]},"abstract":"<jats:p>The likelihood of HIV rebound after stopping antiretroviral therapy (ART) is a combination of the size of HIV reservoirs that persist despite ART and the host immunological and inflammatory factors that control these reservoirs. Therefore, there is a need to comprehensively understand these host factors to develop a strategy to cure HIV infection and prevent viral rebound post-ART.<\/jats:p>","DOI":"10.1128\/mbio.03444-20","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T09:34:50Z","timestamp":1613986490000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":29,"title":["Phospholipid Metabolism Is Associated with Time to HIV Rebound upon Treatment Interruption"],"prefix":"10.1128","volume":"12","author":[{"given":"Leila B.","family":"Giron","sequence":"first","affiliation":[{"name":"The Wistar Institute, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanouil","family":"Papasavvas","sequence":"additional","affiliation":[{"name":"The Wistar Institute, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangfan","family":"Yin","sequence":"additional","affiliation":[{"name":"The Wistar Institute, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron R.","family":"Goldman","sequence":"additional","affiliation":[{"name":"The Wistar Institute, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsin-Yao","family":"Tang","sequence":"additional","affiliation":[{"name":"The Wistar Institute, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clovis S.","family":"Palmer","sequence":"additional","affiliation":[{"name":"The Burnet Institute, Melbourne, Victoria, Australia"},{"name":"Department of Infectious Diseases, Monash University, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan L.","family":"Landay","sequence":"additional","affiliation":[{"name":"Rush University, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan Z.","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medicine, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Koethe","sequence":"additional","affiliation":[{"name":"Vanderbilt University, Nashville, Tennessee, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karam","family":"Mounzer","sequence":"additional","affiliation":[{"name":"Philadelphia FIGHT, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay R.","family":"Kostman","sequence":"additional","affiliation":[{"name":"Philadelphia FIGHT, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Liu","sequence":"additional","affiliation":[{"name":"The Wistar Institute, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis J.","family":"Montaner","sequence":"additional","affiliation":[{"name":"The Wistar Institute, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9945-4314","authenticated-orcid":true,"given":"Mohamed","family":"Abdel-Mohsen","sequence":"additional","affiliation":[{"name":"The Wistar Institute, Philadelphia, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-1022-1"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.10.6540"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3793"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abb5817"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000885"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2019.4025"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0202944"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000566"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.20411\/pai.v2i3.218"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2015.01.013"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001909"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0010064"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-20-0329"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1388-1981(02)00140-3"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2012.06.014"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2014.04.010"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e04-12-1044"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2015.10.013"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4800(86)90019-5"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature09922"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-1835"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-nutr-071816-064732"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.115.002767"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.aaz8240"}],"container-title":["mBio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mBio.03444-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mBio.03444-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T22:31:23Z","timestamp":1646692283000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mBio.03444-20"}},"subtitle":[],"editor":[{"given":"Thomas E.","family":"Smithgall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,2,23]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2,23]]}},"alternative-id":["10.1128\/mBio.03444-20"],"URL":"https:\/\/doi.org\/10.1128\/mbio.03444-20","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.12.09.418814","asserted-by":"object"}]},"ISSN":["2161-2129","2150-7511"],"issn-type":[{"value":"2161-2129","type":"print"},{"value":"2150-7511","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,23]]},"assertion":[{"value":"2020-12-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e03444-20"}}