{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T23:34:03Z","timestamp":1783035243336,"version":"3.54.6"},"reference-count":68,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP20fk0108138"],"award-info":[{"award-number":["JP20fk0108138"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"MEXT | Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP18H02650"],"award-info":[{"award-number":["JP18H02650"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"MEXT | Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP21H02723"],"award-info":[{"award-number":["JP21H02723"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"MEXT | Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP20K16233"],"award-info":[{"award-number":["JP20K16233"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"crossref","award":["JPJSCCB20190010"],"award-info":[{"award-number":["JPJSCCB20190010"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mBio"],"published-print":{"date-parts":[[2022,4,26]]},"abstract":"<jats:p>\n                    Membrane contact sites (MCSs) are key regulators of interorganellar communication and have been widely demonstrated between various organelles. However, studies on MCSs involving mitochondrion-related organelles (MROs), present in some anaerobic parasitic protozoans, remain scarce.\n                    <jats:named-content content-type=\"genus-species\">Entamoeba histolytica<\/jats:named-content>\n                    , the etiological agent of amoebiasis, possesses an MRO called the mitosome.\n                  <\/jats:p>","DOI":"10.1128\/mbio.03849-21","type":"journal-article","created":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T09:01:06Z","timestamp":1649667666000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":10,"title":["Entamoeba histolytica EHD1 Is Involved in Mitosome-Endosome Contact"],"prefix":"10.1128","volume":"13","author":[{"given":"Herbert J.","family":"Santos","sequence":"first","affiliation":[{"name":"Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"},{"name":"Department of Parasitology, National Institute of Infectious Diseases, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Hanadate","sequence":"additional","affiliation":[{"name":"Department of Parasitology, National Institute of Infectious Diseases, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichiro","family":"Imai","sequence":"additional","affiliation":[{"name":"Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruo","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyoshi","family":"Nozaki","sequence":"additional","affiliation":[{"name":"Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan"},{"name":"Department of Parasitology, National Institute of Infectious Diseases, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2017.05.017"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2013.01.028"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09253-3"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.08.030"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature25486"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12830-9"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2018.08.008"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1423718112"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00007-08"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2014.07.034"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/febs.14870"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2016.01.001"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.3390\/genes10050367"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2021.102372"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2005.02.021"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/890674"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2018.00053"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0907106106"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e05-04-0283"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.13144"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00011-10"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2007.00941.x"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep01129"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep08545"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0854.2002.30807.x"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2121-8-3"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0014-5793(01)03241-0"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2017.07.047"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1614075114"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.04.022"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-313X.2008.03571.x"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/35078543"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2015.08.007"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.182857"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature06173"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e09-06-0535"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1986"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M412751200"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2012.98"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-07586-z"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2019.00150"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00040-13"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12334"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R117.000629"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81707-9"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1009551"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201602069"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.204537"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.13-235473"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-13721-5"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2011.11.057"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1601470"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(78)90144-X"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0020048"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2009.01341.x"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001263"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.45.32445"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.672907"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2089"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.3390\/genes10110885"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0166-6851(98)00129-7"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2012.01800.x"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq1006"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty1062"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.639065"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2013.11.025"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/mst010"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp033"}],"container-title":["mBio"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mbio.03849-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mbio.03849-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T09:38:33Z","timestamp":1650965913000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mbio.03849-21"}},"subtitle":[],"editor":[{"given":"Purnima","family":"Bhanot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,4,26]]},"references-count":68,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,4,26]]}},"alternative-id":["10.1128\/mbio.03849-21"],"URL":"https:\/\/doi.org\/10.1128\/mbio.03849-21","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.01.16.476539","asserted-by":"object"}]},"ISSN":["2150-7511"],"issn-type":[{"value":"2150-7511","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,26]]},"assertion":[{"value":"2022-02-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e03849-21"}}