{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T10:03:40Z","timestamp":1790935420409,"version":"4.1.0"},"reference-count":67,"publisher":"Informa UK Limited","issue":"3","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Mol Cell Biol"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1128\/mcb.00885-08","type":"journal-article","created":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T20:54:37Z","timestamp":1228164877000},"page":"881-891","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":39,"title":["Sustained Platelet-Derived Growth Factor Receptor \u03b1 Signaling in Osteoblasts Results in Craniosynostosis by Overactivating the Phospholipase C-\u03b3 Pathway"],"prefix":"10.1080","volume":"29","author":[{"given":"Anne","family":"Moenning","sequence":"first","affiliation":[{"name":"Department of Developmental Pathology, Institute of Pathology, University of Bonn","place":["Bonn, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Ja\u0308ger","sequence":"additional","affiliation":[{"name":"Department of Developmental Pathology, Institute of Pathology, University of Bonn","place":["Bonn, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Egert","sequence":"additional","affiliation":[{"name":"Department of Developmental Pathology, Institute of Pathology, University of Bonn","place":["Bonn, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfram","family":"Kress","sequence":"additional","affiliation":[{"name":"Institut fu\u0308r Humangenetik, Biozentrum","place":["Wu\u0308rzburg, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Wardelmann","sequence":"additional","affiliation":[{"name":"Institute of Pathology, University of Bonn","place":["Bonn, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert","family":"Schorle","sequence":"additional","affiliation":[{"name":"Department of Developmental Pathology, Institute of Pathology, University of Bonn","place":["Bonn, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,3,21]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.143.2.8639"},{"key":"e_1_3_3_3_1","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/00003086-199505000-00034","article-title":"Molecular biology of matrix vesicles.","volume":"314","author":"Anderson H. C.","year":"1995","unstructured":"Anderson, H. C. 1995. Molecular biology of matrix vesicles. Clin. Orthop. Relat. Res. 314:266\u2013280.","journal-title":"Clin. Orthop. Relat. Res."},{"key":"e_1_3_3_4_1","first-page":"2631","article-title":"Osteoblast-related transcription factors Runx2 (Cbfa1\/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells.","volume":"63","author":"Barnes G. L.","year":"2003","unstructured":"Barnes, G. L., A. Javed, S. M. Waller, M. H. Kamal, K. E. Hebert, M. Q. Hassan, A. Bellahcene, A. J. Van Wijnen, M. F. Young, J. B. Lian, G. S. Stein, and L. C. Gerstenfeld. 2003. Osteoblast-related transcription factors Runx2 (Cbfa1\/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Res. 63:2631\u20132637.","journal-title":"Cancer Res."},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.16.12.6926"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0169-6009(92)90707-K"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bies.1069"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1996_033_0150_sicsbv_2.3.co_2"},{"key":"e_1_3_3_9_1","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1387\/ijdb.11061436","article-title":"Role of the extracellular matrix and growth factors in skull morphogenesis and in the pathogenesis of craniosynostosis.","volume":"44","author":"Carinci P.","year":"2000","unstructured":"Carinci, P., E. Becchetti, and M. Bodo. 2000. Role of the extracellular matrix and growth factors in skull morphogenesis and in the pathogenesis of craniosynostosis. Int. J. Dev. Biol. 44:715\u2013723.","journal-title":"Int. J. Dev. Biol."},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.127.8.1671"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2003.11.014"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320310514"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320560327"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(07)00562-3"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.13.7773"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2004.02.010"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200610046"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M106611200"},{"key":"e_1_3_3_19_1","author":"Hall B. K.","year":"1999","unstructured":"Hall, B. K. 1999. Bone. Telford Press, Caldwell, NJ.","journal-title":"Bone."},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)37619-1"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.11.6972"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00453a022"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1079666"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(03)01046-1"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(96)00217-7"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/gene.20014"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2001.0487"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.16.10.5905"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2006.07.024"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1107627"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700122"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.00376"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-475X.1994.20308.x"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1209232"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200407000-00007"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.5650110213"},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.115.1.133"},{"key":"e_1_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001020107"},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi981878u"},{"key":"e_1_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.115.1.289"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.24.20.8847-8861.2004"},{"key":"e_1_3_3_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(199705)209:1<105::AID-AJA10>3.0.CO;2-0"},{"key":"e_1_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvg.20321"},{"key":"e_1_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M108578200"},{"key":"e_1_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.127.9.1845"},{"key":"e_1_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M503942200"},{"key":"e_1_3_3_47_1","first-page":"1916","article-title":"Determination and expression of platelet-derived growth factor-AA in bone cell cultures.","volume":"130","author":"Rydziel S.","year":"1992","unstructured":"Rydziel, S., C. Ladd, T. L. McCarthy, M. Centrella, and E. Canalis. 1992. Determination and expression of platelet-derived growth factor-AA in bone cell cultures. Endocrinology 130:1916\u20131922.","journal-title":"Endocrinology"},{"key":"e_1_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.115.1.123"},{"key":"e_1_3_3_49_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2443.2001.00466.x"},{"key":"e_1_3_3_50_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M314098200"},{"key":"e_1_3_3_51_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.11.4811"},{"key":"e_1_3_3_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/5007"},{"key":"e_1_3_3_53_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.124.14.2691"},{"key":"e_1_3_3_54_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.1.6"},{"key":"e_1_3_3_55_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.127.21.4519"},{"key":"e_1_3_3_56_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.00241"},{"key":"e_1_3_3_57_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.13.1.133-143.1993"},{"key":"e_1_3_3_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1525-1578(10)60510-7"},{"key":"e_1_3_3_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01545"},{"key":"e_1_3_3_60_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200102000-00034"},{"key":"e_1_3_3_61_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.22.9.3149-3156.2002"},{"key":"e_1_3_3_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/35076601"},{"key":"e_1_3_3_63_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.151173398"},{"key":"e_1_3_3_64_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M910329199"},{"key":"e_1_3_3_65_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1997.272.5.C1709"},{"key":"e_1_3_3_66_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.114.17.3093"},{"key":"e_1_3_3_67_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1991.261.2.C348"},{"key":"e_1_3_3_68_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1997.12.1.36"}],"container-title":["Molecular and Cellular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/MCB.00885-08","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1128\/MCB.00885-08","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T21:49:17Z","timestamp":1770414557000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1128\/MCB.00885-08"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":67,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["10.1128\/MCB.00885-08"],"URL":"https:\/\/doi.org\/10.1128\/mcb.00885-08","relation":{},"ISSN":["1098-5549"],"issn-type":[{"value":"1098-5549","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,2]]},"assertion":[{"value":"2008-06-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-11-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}