{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T09:09:55Z","timestamp":1790500195792,"version":"4.1.0"},"reference-count":48,"publisher":"Informa UK Limited","issue":"8","license":[{"start":{"date-parts":[[1997,8,1]],"date-time":"1997-08-01T00:00:00Z","timestamp":870393600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Molecular and Cellular Biology"],"published-print":{"date-parts":[[1997,8,1]]},"DOI":"10.1128\/mcb.17.8.4249","type":"journal-article","created":{"date-parts":[[2015,10,9]],"date-time":"2015-10-09T22:09:00Z","timestamp":1444428540000},"page":"4249-4258","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":56,"title":["Efficient Repression of Endogenous Major Histocompatibility Complex Class II Expression through Dominant Negative CIITA Mutants Isolated by a Functional Selection Strategy"],"prefix":"10.1080","volume":"17","author":[{"given":"S\u00e9verine","family":"Bontron","sequence":"first","affiliation":[{"name":"L. Jeantet Laboratory of Molecular Genetics, Department of Genetics and Microbiology, University of Geneva Medical School, CH-1211 Geneva 4, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Ucla","sequence":"additional","affiliation":[{"name":"L. Jeantet Laboratory of Molecular Genetics, Department of Genetics and Microbiology, University of Geneva Medical School, CH-1211 Geneva 4, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Mach","sequence":"additional","affiliation":[{"name":"L. Jeantet Laboratory of Molecular Genetics, Department of Genetics and Microbiology, University of Geneva Medical School, CH-1211 Geneva 4, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viktor","family":"Steimle","sequence":"additional","affiliation":[{"name":"L. Jeantet Laboratory of Molecular Genetics, Department of Genetics and Microbiology, University of Geneva Medical School, CH-1211 Geneva 4, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,3,29]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1073\/pnas.93.6.2260","volume":"93","author":"Andre I.","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"CIT0002","doi-asserted-by":"crossref","first-page":"10563","DOI":"10.1073\/pnas.90.22.10563","volume":"90","author":"Attardi L. D.","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0092-8674(78)90296-9","volume":"14","author":"Barnstable C. J.","year":"1978","journal-title":"Cell"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1146\/annurev.iy.08.040190.003341","volume":"8","author":"Benoist C.","year":"1990","journal-title":"Annu. Rev.Immunol."},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s004390050403","volume":"99","author":"Bontron S.","year":"1997","journal-title":"Hum. Genet."},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1101\/gad.10.7.826","volume":"10","author":"Bowman T.","year":"1996","journal-title":"GenesDev."},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/0092-8674(85)90246-6","volume":"43","author":"Brent R.","year":"1985","journal-title":"Cell"},{"key":"CIT0008","first-page":"88","volume":"43","author":"Brown J. A.","year":"1996","journal-title":"Immunogenetics"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/1074-7613(95)90113-2","volume":"3","author":"Calnan B. J.","year":"1995","journal-title":"Immunity"},{"key":"CIT0010","doi-asserted-by":"crossref","first-page":"6567","DOI":"10.1073\/pnas.76.12.6567","volume":"76","author":"Charron D. J.","year":"1979","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"4530","DOI":"10.4049\/jimmunol.153.10.4530","volume":"153","author":"De Lerma Barbaro A.","year":"1994","journal-title":"J. Immunol."},{"key":"CIT0012","doi-asserted-by":"crossref","first-page":"3275","DOI":"10.4049\/jimmunol.142.9.3275","volume":"142","author":"Diedrichs M.","year":"1989","journal-title":"J. Immunol."},{"key":"CIT0013","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1093\/emboj\/16.5.1045","volume":"16","author":"Durand B.","year":"1997","journal-title":"EMBO J."},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1146\/annurev.iy.10.040192.000305","volume":"10","author":"Glimcher L. H.","year":"1992","journal-title":"Annu. Rev. Immunol."},{"key":"CIT0015","first-page":"296","volume":"9","author":"G\u00f6nczy P.","year":"1989","journal-title":"Mol. Cell. Biol."},{"key":"CIT0016","first-page":"141","volume-title":"Immunodeficiencies","author":"Griscelli C.","year":"1993"},{"key":"CIT0017","first-page":"1853","volume":"14","author":"Hachiya M.","year":"1994","journal-title":"Anticancer Res."},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/BF00170556","volume":"229","author":"Helbig H.","year":"1991","journal-title":"Graefes. Arch. Clin. Exp. Ophthalmol."},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/329219a0","volume":"329","author":"Herskowitz I.","year":"1987","journal-title":"Nature"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0167-5699(84)90043-4","volume":"5","author":"Janeway C. A.","year":"1984","journal-title":"Immunol. Today"},{"key":"CIT0021","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/0092-8674(93)90730-E","volume":"74","author":"Katz J. D.","year":"1993","journal-title":"Cell"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0959-440X(95)80105-7","volume":"5","author":"Kobe B.","year":"1995","journal-title":"Curr. Opin. Struct. Biol."},{"key":"CIT0023","first-page":"2447","volume":"10","author":"Lalle P.","year":"1995","journal-title":"Oncogene"},{"key":"CIT0024","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1038\/352635a0","volume":"352","author":"Lloyd A.","year":"1991","journal-title":"Nature"},{"key":"CIT0025","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1146\/annurev.immunol.14.1.301","volume":"14","author":"Mach B.","year":"1996","journal-title":"Annu. Rev. Immunol."},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"715","DOI":"10.4049\/jimmunol.139.3.715","volume":"139","author":"Maurer D. H.","year":"1987","journal-title":"J. Immunol."},{"key":"CIT0027","doi-asserted-by":"crossref","first-page":"4150","DOI":"10.1021\/bi00131a035","volume":"31","author":"O\u2019Hare P.","year":"1992","journal-title":"Biochemistry"},{"key":"CIT0028","unstructured":"Otten, L. A., V. Steimle, S. Bontron, and B. Mach. Unpublished data."},{"key":"CIT0029","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0952-7915(96)80069-0","volume":"8","author":"Perlmutter R. M.","year":"1996","journal-title":"Curr. Opin. Immunol."},{"key":"CIT0030","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/S0952-7915(96)80091-4","volume":"8","author":"Platt J. L.","year":"1996","journal-title":"Curr. Opin. Immunol."},{"key":"CIT0031","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/S0092-8674(88)90389-3","volume":"53","author":"Reith W.","year":"1988","journal-title":"Cell"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/0167-5699(95)80048-4","volume":"16","author":"Reith W.","year":"1995","journal-title":"Immunol. Today"},{"key":"CIT0033","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/1074-7613(95)90033-0","volume":"2","author":"Riley J. L.","year":"1995","journal-title":"Immunity"},{"key":"CIT0034","doi-asserted-by":"crossref","first-page":"4961","DOI":"10.1002\/j.1460-2075.1992.tb05603.x","volume":"11","author":"Seipel K.","year":"1992","journal-title":"EMBO J."},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1084\/jem.180.4.1329","volume":"180","author":"Silacci P.","year":"1994","journal-title":"J. Exp. Med."},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1101\/gad.9.9.1021","volume":"9","author":"Steimle V.","year":"1995","journal-title":"Genes Dev."},{"key":"CIT0037","unstructured":"Steimle, V., and B. Mach. Unpublished data."},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0092-8674(05)80090-X","volume":"75","author":"Steimle V.","year":"1993","journal-title":"Cell"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1126\/science.8016643","volume":"265","author":"Steimle V.","year":"1994","journal-title":"Science"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1073\/pnas.82.4.1074","volume":"82","author":"Tabor S.","year":"1985","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"CIT0041","first-page":"466","volume":"8","author":"Takebe Y.","year":"1988","journal-title":"Mol. Cell. Biol."},{"key":"CIT0042","unstructured":"Ucla, C., W. Reith, and B. Mach. Unpublished data."},{"key":"CIT0043","first-page":"5182","volume":"14","author":"Wang P.","year":"1994","journal-title":"Mol. Cell. Biol."},{"key":"CIT0044","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1038\/304358a0","volume":"304","author":"Watson A. J.","year":"1983","journal-title":"Nature"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"10933","DOI":"10.1093\/nar\/16.22.10933","volume":"16","author":"Wilkinson M.","year":"1988","journal-title":"Nucleic Acids"},{"key":"CIT0046","doi-asserted-by":"crossref","first-page":"5249","DOI":"10.4049\/jimmunol.155.11.5249","volume":"155","author":"Yamada K.","year":"1995","journal-title":"J. Immunol."},{"key":"CIT0047","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/1074-7613(95)90034-9","volume":"2","author":"Zhou H.","year":"1995","journal-title":"Immunity"},{"key":"CIT0048","first-page":"77","volume":"171","author":"Ziegler A.","year":"1986","journal-title":"Hlk directed against human HLA class IIantigens. Immunobiology"}],"container-title":["Molecular and Cellular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/MCB.17.8.4249","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1128\/MCB.17.8.4249","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T18:30:57Z","timestamp":1680114657000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1128\/MCB.17.8.4249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,8,1]]},"references-count":48,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1997,8,1]]}},"alternative-id":["10.1128\/MCB.17.8.4249"],"URL":"https:\/\/doi.org\/10.1128\/mcb.17.8.4249","relation":{},"ISSN":["1098-5549"],"issn-type":[{"value":"1098-5549","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,8,1]]},"assertion":[{"value":"1997-08-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}