{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:57:19Z","timestamp":1791424639419,"version":"4.3.3"},"reference-count":59,"publisher":"Informa UK Limited","issue":"8","license":[{"start":{"date-parts":[[1997,8,1]],"date-time":"1997-08-01T00:00:00Z","timestamp":870393600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Mol Cell Biol"],"published-print":{"date-parts":[[1997,8]]},"DOI":"10.1128\/mcb.17.8.4782","type":"journal-article","created":{"date-parts":[[2015,10,9]],"date-time":"2015-10-09T18:09:00Z","timestamp":1444414140000},"page":"4782-4791","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":348,"title":["E2A Deficiency Leads to Abnormalities in \u03b1\u03b2 T-Cell Development and to Rapid Development of T-Cell Lymphomas"],"prefix":"10.1080","volume":"17","author":[{"given":"Gretchen","family":"Bain","sequence":"first","affiliation":[{"name":"Department of Biology, University of California","place":["San Diego, La Jolla"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac","family":"Engel","sequence":"additional","affiliation":[{"name":"Department of Biology, University of California","place":["San Diego, La Jolla"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Els C.","family":"Robanus Maandag","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics, The Netherlands Cancer Institute","place":["Amsterdam, The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hein P. J.","family":"te Riele","sequence":"additional","affiliation":[{"name":"Department of Molecular Genetics, The Netherlands Cancer Institute","place":["Amsterdam, The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph R.","family":"Voland","sequence":"additional","affiliation":[{"name":"Department of Biology, University of California","place":["San Diego, La Jolla"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie L.","family":"Sharp","sequence":"additional","affiliation":[{"name":"Department of Biology, University of California","place":["San Diego, La Jolla"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerold","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, University of California","place":["San Diego, La Jolla"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Huey","sequence":"additional","affiliation":[{"name":"Cancer Center, Department of Laboratory Medicine, University of California, San Francisco","place":["San Francisco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Pinkel","sequence":"additional","affiliation":[{"name":"Cancer Center, Department of Laboratory Medicine, University of California, San Francisco","place":["San Francisco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelis","family":"Murre","sequence":"additional","affiliation":[{"name":"Department of Biology, University of California","place":["San Diego, La Jolla"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,3,29]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.17.8063"},{"key":"e_1_2_1_3_1","unstructured":"Bain G. and I. Engel. Unpublished results."},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.13.6.3522-3529.1993"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(94)90077-9"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80421-5"},{"key":"e_1_2_1_7_1","unstructured":"Bain G. Unpublished results."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.24.10128"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.2870010303"},{"key":"e_1_2_1_10_1","unstructured":"Brady H. and A. Berns. Unpublished results."},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.11.7.3633-3641.1991"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1990.tb08126.x"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(90)90088-V"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80438-0"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.152.10.4783"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.178.1.257"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.173.5.1213"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2105528"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.09.040191.003525"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.10.8.948"},{"key":"e_1_2_1_21_1","first-page":"1256","article-title":"Enhancer-binding activity of the tal-1 oncoprotein in association with the E47\/E12 helix-loop-helix proteins","volume":"14","author":"Hsu H. L.","year":"1991","unstructured":"Hsu, H. L., J. T. Cheng, Q. Chen, and R. Baer. 1991. Enhancer-binding activity of the tal-1 oncoprotein in association with the E47\/E12 helix-loop-helix proteins. Mol. Cell. Biol. 14:1256\u20131265.","journal-title":"Mol. Cell. Biol."},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.13.5947"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1359641"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(89)90935-5"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90620-E"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90138-G"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.2.519"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.16.1.121"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(89)90404-2"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830250643"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.16.5.2394"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/360225a0"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90030-G"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(89)90682-X"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(89)90434-0"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.11.2.1156-1160.1991"},{"key":"e_1_2_1_37_1","first-page":"1798","article-title":"Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix-loop-helix factor E47 and the homeobox factor STF-1","volume":"8","author":"Peers B.","year":"1994","unstructured":"Peers, B., J. Leonard, S. Sharma, G. Teitelman, and M. R. Montminy. 1994. Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix-loop-helix factor E47 and the homeobox factor STF-1. Mol. Endocrinol. 8:1798\u20131806.","journal-title":"Mol. Endocrinol."},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.154.10.5103"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.990190104"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.11.2.1040-1047.1991"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.13.2.792-800.1993"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.16.7583"},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.183.1.187"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.13.9.5620-5628.1993"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.15.8.4518"},{"key":"e_1_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90029-C"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910530628"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90653-G"},{"key":"e_1_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(94)90078-7"},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.10.10.5027-5035.1990"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.08.040190.002531"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.12.4722"},{"key":"e_1_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.13.5952"},{"key":"e_1_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.10.4.1564-1572.1990"},{"key":"e_1_2_1_55_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.140.5.1461"},{"key":"e_1_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.24.11416"},{"key":"e_1_2_1_57_1","first-page":"1437","article-title":"Products of the tal2 oncogene in leukemic T cells: bHLH phosphoproteins with DNA-binding activity","volume":"9","author":"Xia Y.","year":"1994","unstructured":"Xia, Y., L. Y. Hwang, M. H. Cobb, and R. Baer. 1994. Products of the tal2 oncogene in leukemic T cells: bHLH phosphoproteins with DNA-binding activity. Oncogene 9:1437\u20131446.","journal-title":"Oncogene"},{"key":"e_1_2_1_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(94)90076-0"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7541554"},{"key":"e_1_2_1_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-7915(96)80060-4"}],"container-title":["Molecular and Cellular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/MCB.17.8.4782","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1128\/MCB.17.8.4782","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T16:52:23Z","timestamp":1770915143000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1128\/MCB.17.8.4782"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,8]]},"references-count":59,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1997,8]]}},"alternative-id":["10.1128\/MCB.17.8.4782"],"URL":"https:\/\/doi.org\/10.1128\/mcb.17.8.4782","relation":{},"ISSN":["1098-5549"],"issn-type":[{"value":"1098-5549","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,8]]},"assertion":[{"value":"1997-08-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}