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The combination of a macrolide (erythromycin, azithromycin, or clarithromycin) with rifampin has been the recommended treatment for foals with clinical signs of infection caused by\n                    <jats:italic>R. equi<\/jats:italic>\n                    since the early 1980s with, until recently, only rare reports of resistance. Resistance to macrolides and rifampin in isolates of\n                    <jats:italic>R. equi<\/jats:italic>\n                    cultured from horses is increasing, with isolates resistant to all macrolides and rifampin now being cultured from up to 40% of infected foals at some farms. This text  reviews the available data regarding antimicrobial resistance in\n                    <jats:italic>R. equi<\/jats:italic>\n                    , with emphasis on the molecular mechanisms of the recent emergence of resistance to macrolides and rifampin in equine isolates of\n                    <jats:italic>R. equi<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1128\/microbiolspec.arba-0004-2016","type":"journal-article","created":{"date-parts":[[2017,10,20]],"date-time":"2017-10-20T08:45:17Z","timestamp":1508489117000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":33,"title":["Antimicrobial Resistance in\n                    <i>Rhodococcus equi<\/i>"],"prefix":"10.1128","volume":"5","author":[{"given":"Steeve","family":"Gigu\u00e8re","sequence":"first","affiliation":[{"name":"Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA 30605"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Londa J.","family":"Berghaus","sequence":"additional","affiliation":[{"name":"Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA 30605"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer M.","family":"Willingham-Lane","sequence":"additional","affiliation":[{"name":"Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA 30605"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","unstructured":"Arlotti M Zoboli G Moscatelli GL Magnani G Maserati R Borghi V Andreoni M Libanore M Bonazzi L Piscina A Ciammarughi R. 1996. 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