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Recently, the World Health Organization published its first fungal pathogen priority list, with\n                    <jats:italic>Candida<\/jats:italic>\n                    species listed in medium, high, and critical priority categories. This review is a synthesis of information and recent advances in our understanding of two of these species\n                    <jats:italic>\u2014Candida albicans<\/jats:italic>\n                    and\n                    <jats:italic>Candida glabrata<\/jats:italic>\n                    . Of these,\n                    <jats:italic>C. albicans<\/jats:italic>\n                    is the most common cause of candidemia around the world and is categorized as a critical priority pathogen.\n                    <jats:italic>C. glabrata<\/jats:italic>\n                    is considered a high-priority pathogen and has become an increasingly important cause of candidemia in recent years. It is now the second most common causative agent of candidemia in many geographical regions. Despite their differences and phylogenetic divergence, they are successful as pathogens and commensals of humans. Both species can cause a broad variety of infections, ranging from superficial to potentially lethal systemic infections. While they share similarities in certain infection strategies, including tissue adhesion and invasion, they differ significantly in key aspects of their biology, interaction with immune cells, host damage strategies, and metabolic adaptations. Here we provide insights on key aspects of their biology, epidemiology, commensal and pathogenic lifestyles, interactions with the immune system, and antifungal resistance.\n                  <\/jats:p>","DOI":"10.1128\/mmbr.00021-23","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T09:05:23Z","timestamp":1717491923000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":179,"title":["<i>Candida albicans<\/i>\n                    and\n                    <i>Candida glabrata<\/i>\n                    : global priority pathogens"],"prefix":"10.1128","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6322-6458","authenticated-orcid":false,"given":"Myrto","family":"Katsipoulaki","sequence":"first","affiliation":[{"name":"Department of Microbial Pathogenicity Mechanisms, Hans Knoell Institute, Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4154-7160","authenticated-orcid":false,"given":"Mark H. 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