{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:21:41Z","timestamp":1792790501436,"version":"4.5.0"},"reference-count":623,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Microbiol Mol Biol Rev"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>The HIV genome encodes a small number of viral proteins (i.e., 16), invariably establishing cooperative associations among HIV proteins and between HIV and host proteins, to invade host cells and hijack their internal machineries. As a known example, the HIV envelope glycoprotein GP120 is closely associated with GP41 for viral entry. From a genome-wide perspective, a hypothesis can be worked out to determine whether 16 HIV proteins could develop 120 possible pairwise associations either by physical interactions or by functional associations mediated via HIV or host molecules. Here, we present the first systematic review of experimental evidence on HIV genome-wide protein associations using a large body of publications accumulated over the past 3 decades. Of 120 possible pairwise associations between 16 HIV proteins, at least 34 physical interactions and 17 functional associations have been identified. To achieve efficient viral replication and infection, HIV protein associations play essential roles (e.g., cleavage, inhibition, and activation) during the HIV life cycle. In either a dispensable or an indispensable manner, each HIV protein collaborates with another viral protein to accomplish specific activities that precisely take place at the proper stages of the HIV life cycle. In addition, HIV genome-wide protein associations have an impact on anti-HIV inhibitors due to the extensive cross talk between drug-inhibited proteins and other HIV proteins. Overall, this study presents for the first time a comprehensive overview of HIV genome-wide protein associations, highlighting meticulous collaborations between all viral proteins during the HIV life cycle.<\/jats:p>","DOI":"10.1128\/mmbr.00065-15","type":"journal-article","created":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T22:29:11Z","timestamp":1467239351000},"page":"679-731","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":91,"title":["HIV Genome-Wide Protein Associations: a Review of 30 Years of Research"],"prefix":"10.1128","volume":"80","author":[{"given":"Guangdi","family":"Li","sequence":"first","affiliation":[{"name":"Department of Metabolism and Endocrinology, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China"},{"name":"KU Leuven-University of Leuven, Rega Institute for Medical Research, Department of Microbiology and Immunology, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"De Clercq","sequence":"additional","affiliation":[{"name":"KU Leuven-University of Leuven, Rega Institute for Medical Research, Department of Microbiology and Immunology, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2747"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3490"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2008.04.008"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2011.04.042"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature10719"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.07.032"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2008.10.004"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1152725"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.010033"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009276"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.66.12.7193-7200.1992"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.67.12.7238-7245.1993"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1996.0491"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(00)80056-8"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.65.12.6387-6396.1991"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.64.11.5585-5593.1990"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000869"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.05933-11"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a006866"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2013.09.004"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2015.09.003"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a006882"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a006890"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-8-52"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2014.12.001"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2011.11.002"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr400120z"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a006916"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a006924"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2012.11.006"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku1126"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02584-06"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1462399409001343"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01437-10"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2008.04.017"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0400830101"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1089591"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00395-07"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0906652106"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00079-10"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00960-10"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00040-08"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12977-015-0148-6"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.04.033"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2010.09.003"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3475"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.2711"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0911004107"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13808"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.02.012"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01681-13"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1245625"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1245627"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003218"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.3051"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0122111"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1307382110"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1254426"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1016113108"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-5-111"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004595"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi800227z"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-10-44"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M806099200"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.9.4921-4926.2004"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms9167"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3158"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.8.3548-3554.2000"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.7.3338-3349.2002"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.69.3.1984-1989.1995"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003739"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.10.5157-5169.2004"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2015.01.018"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.06047-11"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.70.1.341-351.1996"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.68.3.1689-1696.1994"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.1.343"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.1.106-115.2005"},{"key":"e_1_3_3_81_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.2.1026-1031.2004"},{"key":"e_1_3_3_82_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1226359"},{"key":"e_1_3_3_83_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03584-14"},{"key":"e_1_3_3_84_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2007.06.046"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.80.5.2405-2417.2006"},{"key":"e_1_3_3_86_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI67399"},{"key":"e_1_3_3_87_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-06-2212"},{"key":"e_1_3_3_88_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000432453.60733.b2"},{"key":"e_1_3_3_89_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0048781"},{"key":"e_1_3_3_90_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2013.07.039"},{"key":"e_1_3_3_91_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.67.1.277-287.1993"},{"key":"e_1_3_3_92_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.22.13153"},{"key":"e_1_3_3_93_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000432452.83604.59"},{"key":"e_1_3_3_94_2","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.627"},{"key":"e_1_3_3_95_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2006.03.027"},{"key":"e_1_3_3_96_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.8.3626-3635.2001"},{"key":"e_1_3_3_97_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3503"},{"key":"e_1_3_3_98_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1102943108"},{"key":"e_1_3_3_99_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000327"},{"key":"e_1_3_3_100_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-7-96"},{"key":"e_1_3_3_101_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2007.12.017"},{"key":"e_1_3_3_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(01)02945-3"},{"key":"e_1_3_3_103_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M806241200"},{"key":"e_1_3_3_104_2","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20071279"},{"key":"e_1_3_3_105_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.3.2126-2135.1999"},{"key":"e_1_3_3_106_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2012.12.007"},{"key":"e_1_3_3_107_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.10.5045-5055.2004"},{"key":"e_1_3_3_108_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01471-15"},{"key":"e_1_3_3_109_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.10.5056-5067.2004"},{"key":"e_1_3_3_110_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00519-07"},{"key":"e_1_3_3_111_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.16.11283"},{"key":"e_1_3_3_112_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.50.33781"},{"key":"e_1_3_3_113_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00250a036"},{"key":"e_1_3_3_114_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.13.6700"},{"key":"e_1_3_3_115_2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.1997.13.533"},{"key":"e_1_3_3_116_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2006.10.007"},{"key":"e_1_3_3_117_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1989.tb08488.x"},{"key":"e_1_3_3_118_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.7.3301-3313.2001"},{"key":"e_1_3_3_119_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80828-4"},{"key":"e_1_3_3_120_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M600290200"},{"key":"e_1_3_3_121_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi801386r"},{"key":"e_1_3_3_122_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2007.10.001"},{"key":"e_1_3_3_123_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1995.0520"},{"key":"e_1_3_3_124_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.25.15005"},{"key":"e_1_3_3_125_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.19.8980-8988.2000"},{"key":"e_1_3_3_126_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi951707e"},{"key":"e_1_3_3_127_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1937"},{"key":"e_1_3_3_128_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00583-08"},{"key":"e_1_3_3_129_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2011.12.034"},{"key":"e_1_3_3_130_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M304608200"},{"key":"e_1_3_3_131_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000669"},{"key":"e_1_3_3_132_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp226"},{"key":"e_1_3_3_133_2","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20040914"},{"key":"e_1_3_3_134_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm542"},{"key":"e_1_3_3_135_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.19.8938-8945.2000"},{"key":"e_1_3_3_136_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.70.12.8701-8709.1996"},{"key":"e_1_3_3_137_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.70.8.5297-5305.1996"},{"key":"e_1_3_3_138_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.6.2594-2602.2000"},{"key":"e_1_3_3_139_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-79-8-1945"},{"key":"e_1_3_3_140_2","doi-asserted-by":"publisher","DOI":"10.2174\/157016207781662443"},{"key":"e_1_3_3_141_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03440-14"},{"key":"e_1_3_3_142_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.3.2499-2508.1999"},{"key":"e_1_3_3_143_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.8.3637-3645.2002"},{"key":"e_1_3_3_144_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.6.2675-2683.2001"},{"key":"e_1_3_3_145_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2010.05.033"},{"key":"e_1_3_3_146_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.6.1224"},{"key":"e_1_3_3_147_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt934"},{"key":"e_1_3_3_148_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/18.21.6106"},{"key":"e_1_3_3_149_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1020971823562"},{"key":"e_1_3_3_150_2","doi-asserted-by":"publisher","DOI":"10.1089\/088922204323048140"},{"key":"e_1_3_3_151_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.69.8.5048-5056.1995"},{"key":"e_1_3_3_152_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.69.7.4053-4059.1995"},{"key":"e_1_3_3_153_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.18.9912-9921.2003"},{"key":"e_1_3_3_154_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-3-4"},{"key":"e_1_3_3_155_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-2-11"},{"key":"e_1_3_3_156_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.23.14523"},{"key":"e_1_3_3_157_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-1-33"},{"key":"e_1_3_3_158_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2000.3709"},{"key":"e_1_3_3_159_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1998.2430"},{"key":"e_1_3_3_160_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.4.3037-3044.1998"},{"key":"e_1_3_3_161_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2009.11.038"},{"key":"e_1_3_3_162_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.68.12.7676-7683.1994"},{"key":"e_1_3_3_163_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2007.03.073"},{"key":"e_1_3_3_164_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2014.02.004"},{"key":"e_1_3_3_165_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.80.8.3712-3720.2006"},{"key":"e_1_3_3_166_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-5-114"},{"key":"e_1_3_3_167_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.71.7.5382-5390.1997"},{"key":"e_1_3_3_168_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2006.05.006"},{"key":"e_1_3_3_169_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000046"},{"key":"e_1_3_3_170_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1579"},{"key":"e_1_3_3_171_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-008-7540-5"},{"key":"e_1_3_3_172_2","doi-asserted-by":"publisher","DOI":"10.1042\/0264-6021:3610557"},{"key":"e_1_3_3_173_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1738845"},{"key":"e_1_3_3_174_2","doi-asserted-by":"publisher","DOI":"10.2119\/molmed.2009.00133"},{"key":"e_1_3_3_175_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M609864200"},{"key":"e_1_3_3_176_2","doi-asserted-by":"publisher","DOI":"10.1093\/protein\/gzp060"},{"key":"e_1_3_3_177_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0506924102"},{"key":"e_1_3_3_178_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M406307200"},{"key":"e_1_3_3_179_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M303594200"},{"key":"e_1_3_3_180_2","doi-asserted-by":"publisher","DOI":"10.4161\/nucl.11300"},{"key":"e_1_3_3_181_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004155"},{"key":"e_1_3_3_182_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90097-7"},{"key":"e_1_3_3_183_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/17.9.2699"},{"key":"e_1_3_3_184_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1996.0302"},{"key":"e_1_3_3_185_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.15.7311"},{"key":"e_1_3_3_186_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.17.8348-8352.2001"},{"key":"e_1_3_3_187_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01928-06"},{"key":"e_1_3_3_188_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2012.09.008"},{"key":"e_1_3_3_189_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.12.2.175"},{"key":"e_1_3_3_190_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-3144"},{"key":"e_1_3_3_191_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkg364"},{"key":"e_1_3_3_192_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.2.1469-1480.2003"},{"key":"e_1_3_3_193_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(03)00472-8"},{"key":"e_1_3_3_194_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.8.6670-6679.1999"},{"key":"e_1_3_3_195_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.71.8.6225-6229.1997"},{"key":"e_1_3_3_196_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01899-09"},{"key":"e_1_3_3_197_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2008.07.079"},{"key":"e_1_3_3_198_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00451-12"},{"key":"e_1_3_3_199_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.387944"},{"key":"e_1_3_3_200_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2008.07.037"},{"key":"e_1_3_3_201_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.533281"},{"key":"e_1_3_3_202_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-8-104"},{"key":"e_1_3_3_203_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-8-98"},{"key":"e_1_3_3_204_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02382-09"},{"key":"e_1_3_3_205_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002439"},{"key":"e_1_3_3_206_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10714"},{"key":"e_1_3_3_207_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1516920112"},{"key":"e_1_3_3_208_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.07177-11"},{"key":"e_1_3_3_209_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00682-09"},{"key":"e_1_3_3_210_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1061548"},{"key":"e_1_3_3_211_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1902"},{"key":"e_1_3_3_212_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-6405-10-31"},{"key":"e_1_3_3_213_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.041186-0"},{"key":"e_1_3_3_214_2","doi-asserted-by":"publisher","DOI":"10.3390\/v7062760"},{"key":"e_1_3_3_215_2","doi-asserted-by":"publisher","DOI":"10.4161\/nucl.2.2.15018"},{"key":"e_1_3_3_216_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11481-011-9267-6"},{"key":"e_1_3_3_217_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms8244"},{"key":"e_1_3_3_218_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.98.4.1781"},{"key":"e_1_3_3_219_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12977-014-0121-9"},{"key":"e_1_3_3_220_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2011.04.026"},{"key":"e_1_3_3_221_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M005197200"},{"key":"e_1_3_3_222_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80939-3"},{"key":"e_1_3_3_223_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature09131"},{"key":"e_1_3_3_224_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(03)00725-7"},{"key":"e_1_3_3_225_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(01)00158-3"},{"key":"e_1_3_3_226_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.12.8425"},{"key":"e_1_3_3_227_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2008.08.013"},{"key":"e_1_3_3_228_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2014.06.019"},{"key":"e_1_3_3_229_2","doi-asserted-by":"publisher","DOI":"10.3390\/v5041143"},{"key":"e_1_3_3_230_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2012.06.021"},{"key":"e_1_3_3_231_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-11-54"},{"key":"e_1_3_3_232_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.20.10444-10454.2002"},{"key":"e_1_3_3_233_2","doi-asserted-by":"publisher","DOI":"10.1089\/dna.2007.0707"},{"key":"e_1_3_3_234_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0509417103"},{"key":"e_1_3_3_235_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2006.09.026"},{"key":"e_1_3_3_236_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-06-289215"},{"key":"e_1_3_3_237_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.12.011"},{"key":"e_1_3_3_238_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2007.05.043"},{"key":"e_1_3_3_239_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2014.08.021"},{"key":"e_1_3_3_240_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.16.8079-8089.2002"},{"key":"e_1_3_3_241_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.50.33414"},{"key":"e_1_3_3_242_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2255"},{"key":"e_1_3_3_243_2","doi-asserted-by":"publisher","DOI":"10.1038\/45272"},{"key":"e_1_3_3_244_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2004.09.029"},{"key":"e_1_3_3_245_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2000.3768"},{"key":"e_1_3_3_246_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.07199-11"},{"key":"e_1_3_3_247_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.24.17309"},{"key":"e_1_3_3_248_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M207439200"},{"key":"e_1_3_3_249_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-4-84"},{"key":"e_1_3_3_250_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.6.3557-3564.2005"},{"key":"e_1_3_3_251_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr500452k"},{"key":"e_1_3_3_252_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.2000.0593"},{"key":"e_1_3_3_253_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.10.8252-8256.1998"},{"key":"e_1_3_3_254_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(00)80120-7"},{"key":"e_1_3_3_255_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M408643200"},{"key":"e_1_3_3_256_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600770"},{"key":"e_1_3_3_257_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02257-06"},{"key":"e_1_3_3_258_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0900012106"},{"key":"e_1_3_3_259_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2007.09.005"},{"key":"e_1_3_3_260_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-009-0444-3"},{"key":"e_1_3_3_261_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.38.24898"},{"key":"e_1_3_3_262_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-3-48"},{"key":"e_1_3_3_263_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.2001.1129"},{"key":"e_1_3_3_264_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-7-18"},{"key":"e_1_3_3_265_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-012414-040445"},{"key":"e_1_3_3_266_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1500447"},{"key":"e_1_3_3_267_2","doi-asserted-by":"publisher","DOI":"10.1038\/90959"},{"key":"e_1_3_3_268_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-3-47"},{"key":"e_1_3_3_269_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7601074"},{"key":"e_1_3_3_270_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M603336200"},{"key":"e_1_3_3_271_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.5.2222-2231.2004"},{"key":"e_1_3_3_272_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.3.1120"},{"key":"e_1_3_3_273_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7801128"},{"key":"e_1_3_3_274_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.17.9819"},{"key":"e_1_3_3_275_2","doi-asserted-by":"publisher","DOI":"10.1007\/82_2015_435"},{"key":"e_1_3_3_276_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1001280"},{"key":"e_1_3_3_277_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0060734"},{"key":"e_1_3_3_278_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0962-8924(02)02402-9"},{"key":"e_1_3_3_279_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2008.10.013"},{"key":"e_1_3_3_280_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.4.1834-1841.2001"},{"key":"e_1_3_3_281_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature04817"},{"key":"e_1_3_3_282_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.70.12.8263-8269.1996"},{"key":"e_1_3_3_283_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.18.9112-9123.2002"},{"key":"e_1_3_3_284_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M703122200"},{"key":"e_1_3_3_285_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.20.9727-9731.2000"},{"key":"e_1_3_3_286_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.04.063"},{"key":"e_1_3_3_287_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1996.0240"},{"key":"e_1_3_3_288_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2014.04.012"},{"key":"e_1_3_3_289_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2011.04.029"},{"key":"e_1_3_3_290_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2009.04.007"},{"key":"e_1_3_3_291_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2011.04.055"},{"key":"e_1_3_3_292_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.66.8.4966-4971.1992"},{"key":"e_1_3_3_293_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.71.2.1443-1452.1997"},{"key":"e_1_3_3_294_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.18.8670-8679.2000"},{"key":"e_1_3_3_295_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01469-05"},{"key":"e_1_3_3_296_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.70.10.6547-6556.1996"},{"key":"e_1_3_3_297_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1516618113"},{"key":"e_1_3_3_298_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0602941103"},{"key":"e_1_3_3_299_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.71.6.4409-4418.1997"},{"key":"e_1_3_3_300_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2008.10.047"},{"key":"e_1_3_3_301_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.16.7252-7265.2001"},{"key":"e_1_3_3_302_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-79-5-1069"},{"key":"e_1_3_3_303_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-009-0520-8"},{"key":"e_1_3_3_304_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.71.12.9358-9365.1997"},{"key":"e_1_3_3_305_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.23.11055-11066.2000"},{"key":"e_1_3_3_306_2","doi-asserted-by":"publisher","DOI":"10.4161\/rna.29546"},{"key":"e_1_3_3_307_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.12.5504-5517.2001"},{"key":"e_1_3_3_308_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M312426200"},{"key":"e_1_3_3_309_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M313093200"},{"key":"e_1_3_3_310_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(03)00353-8"},{"key":"e_1_3_3_311_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2008.04.012"},{"key":"e_1_3_3_312_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-82-3-561"},{"key":"e_1_3_3_313_2","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1996.0061"},{"key":"e_1_3_3_314_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.49.30753"},{"key":"e_1_3_3_315_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.1.592-600.1999"},{"key":"e_1_3_3_316_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01691-09"},{"key":"e_1_3_3_317_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.68.3.1926-1934.1994"},{"key":"e_1_3_3_318_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.12.5395-5402.2000"},{"key":"e_1_3_3_319_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00947-07"},{"key":"e_1_3_3_320_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(96)01470-6"},{"key":"e_1_3_3_321_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.12.9992-9999.1999"},{"key":"e_1_3_3_322_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.13.6198-6202.2000"},{"key":"e_1_3_3_323_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.13.9083"},{"key":"e_1_3_3_324_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.67.12.7229-7237.1993"},{"key":"e_1_3_3_325_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.69.5.2759-2764.1995"},{"key":"e_1_3_3_326_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.70.1.159-164.1996"},{"key":"e_1_3_3_327_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi801794v"},{"key":"e_1_3_3_328_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.21.10537-10542.2001"},{"key":"e_1_3_3_329_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm901106t"},{"key":"e_1_3_3_330_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-1-26"},{"key":"e_1_3_3_331_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.69.11.6873-6879.1995"},{"key":"e_1_3_3_332_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-11-9"},{"key":"e_1_3_3_333_2","doi-asserted-by":"publisher","DOI":"10.1089\/08892220150217193"},{"key":"e_1_3_3_334_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.6.5271-5275.1998"},{"key":"e_1_3_3_335_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.13.6162-6167.2000"},{"key":"e_1_3_3_336_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.1.362-374.2001"},{"key":"e_1_3_3_337_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M312453200"},{"key":"e_1_3_3_338_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002442"},{"key":"e_1_3_3_339_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00695-15"},{"key":"e_1_3_3_340_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M303679200"},{"key":"e_1_3_3_341_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01150-08"},{"key":"e_1_3_3_342_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(99)80284-X"},{"key":"e_1_3_3_343_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.9.4625-4633.2002"},{"key":"e_1_3_3_344_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.12.6287-6296.2004"},{"key":"e_1_3_3_345_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2013.09.028"},{"key":"e_1_3_3_346_2","doi-asserted-by":"publisher","DOI":"10.1186\/1478-811X-10-39"},{"key":"e_1_3_3_347_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.3.1069-1079.2004"},{"key":"e_1_3_3_348_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01796-06"},{"key":"e_1_3_3_349_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2008.07.015"},{"key":"e_1_3_3_350_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2006.10.073"},{"key":"e_1_3_3_351_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01197-09"},{"key":"e_1_3_3_352_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.22.13839-13847.2005"},{"key":"e_1_3_3_353_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1355838201002023"},{"key":"e_1_3_3_354_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.09.057"},{"key":"e_1_3_3_355_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.399865"},{"key":"e_1_3_3_356_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2011.04.063"},{"key":"e_1_3_3_357_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.1.541-546.2000"},{"key":"e_1_3_3_358_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2015.01.015"},{"key":"e_1_3_3_359_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.7.3046-3057.2000"},{"key":"e_1_3_3_360_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1994.1339"},{"key":"e_1_3_3_361_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi2017969"},{"key":"e_1_3_3_362_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2011.04.072"},{"key":"e_1_3_3_363_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02151-13"},{"key":"e_1_3_3_364_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.10.8527-8540.1999"},{"key":"e_1_3_3_365_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0908661107"},{"key":"e_1_3_3_366_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01809-10"},{"key":"e_1_3_3_367_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2013.07.011"},{"key":"e_1_3_3_368_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.14.7553-7564.2004"},{"key":"e_1_3_3_369_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M601189200"},{"key":"e_1_3_3_370_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M301840200"},{"key":"e_1_3_3_371_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9084(03)00045-2"},{"key":"e_1_3_3_372_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.11.5043-5048.2001"},{"key":"e_1_3_3_373_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.24.13111-13115.2002"},{"key":"e_1_3_3_374_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.421842"},{"key":"e_1_3_3_375_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-10-80"},{"key":"e_1_3_3_376_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-3-33"},{"key":"e_1_3_3_377_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01260-12"},{"key":"e_1_3_3_378_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.560193"},{"key":"e_1_3_3_379_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01912-07"},{"key":"e_1_3_3_380_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2015.12.001"},{"key":"e_1_3_3_381_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature15400"},{"key":"e_1_3_3_382_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000339"},{"key":"e_1_3_3_383_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01562-10"},{"key":"e_1_3_3_384_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027466"},{"key":"e_1_3_3_385_2","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201592484"},{"key":"e_1_3_3_386_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-10-79"},{"key":"e_1_3_3_387_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0096950"},{"key":"e_1_3_3_388_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku1232"},{"key":"e_1_3_3_389_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-5-39"},{"key":"e_1_3_3_390_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00653-6"},{"key":"e_1_3_3_391_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.131059198"},{"key":"e_1_3_3_392_2","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwu064"},{"key":"e_1_3_3_393_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2015.02.007"},{"key":"e_1_3_3_394_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3156"},{"key":"e_1_3_3_395_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2007.01.004"},{"key":"e_1_3_3_396_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.3033"},{"key":"e_1_3_3_397_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature10693"},{"key":"e_1_3_3_398_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2011.11.010"},{"key":"e_1_3_3_399_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.2378"},{"key":"e_1_3_3_400_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0900979106"},{"key":"e_1_3_3_401_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms3593"},{"key":"e_1_3_3_402_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02369-15"},{"key":"e_1_3_3_403_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00651-09"},{"key":"e_1_3_3_404_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2008.06.061"},{"key":"e_1_3_3_405_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01898-08"},{"key":"e_1_3_3_406_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02318-09"},{"key":"e_1_3_3_407_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.4.3460-3466.1999"},{"key":"e_1_3_3_408_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.45.29879"},{"key":"e_1_3_3_409_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.70.10.6701-6708.1996"},{"key":"e_1_3_3_410_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M107322200"},{"key":"e_1_3_3_411_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.2849"},{"key":"e_1_3_3_412_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep09867"},{"key":"e_1_3_3_413_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep04450"},{"key":"e_1_3_3_414_2","doi-asserted-by":"publisher","DOI":"10.2174\/0929867322666150209152057"},{"key":"e_1_3_3_415_2","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.4199"},{"key":"e_1_3_3_416_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2011.04.053"},{"key":"e_1_3_3_417_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M009076200"},{"key":"e_1_3_3_418_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1995.tb00183.x"},{"key":"e_1_3_3_419_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M601128200"},{"key":"e_1_3_3_420_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2007.03.004"},{"key":"e_1_3_3_421_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-04-086017"},{"key":"e_1_3_3_422_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.600031"},{"key":"e_1_3_3_423_2","doi-asserted-by":"publisher","DOI":"10.1002\/prot.22986"},{"key":"e_1_3_3_424_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-9-47"},{"key":"e_1_3_3_425_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-06-2084"},{"key":"e_1_3_3_426_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1995.tb07024.x"},{"key":"e_1_3_3_427_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2015.10.023"},{"key":"e_1_3_3_428_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003342"},{"key":"e_1_3_3_429_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.22.9052"},{"key":"e_1_3_3_430_2","doi-asserted-by":"publisher","DOI":"10.1128\/mr.59.1.63-93.1995"},{"key":"e_1_3_3_431_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1796"},{"key":"e_1_3_3_432_2","doi-asserted-by":"publisher","DOI":"10.1038\/31405"},{"key":"e_1_3_3_433_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05580"},{"key":"e_1_3_3_434_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2012.08732.x"},{"key":"e_1_3_3_435_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.11.056"},{"key":"e_1_3_3_436_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M607302200"},{"key":"e_1_3_3_437_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01238-09"},{"key":"e_1_3_3_438_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.07224-11"},{"key":"e_1_3_3_439_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1112391109"},{"key":"e_1_3_3_440_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep07025"},{"key":"e_1_3_3_441_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004767"},{"key":"e_1_3_3_442_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004932"},{"key":"e_1_3_3_443_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13612"},{"key":"e_1_3_3_444_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature14264"},{"key":"e_1_3_3_445_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005369"},{"key":"e_1_3_3_446_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1192819"},{"key":"e_1_3_3_447_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00461-12"},{"key":"e_1_3_3_448_2","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1623"},{"key":"e_1_3_3_449_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm3002247"},{"key":"e_1_3_3_450_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1506755112"},{"key":"e_1_3_3_451_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003895"},{"key":"e_1_3_3_452_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2007.01101.x"},{"key":"e_1_3_3_453_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.9.3384"},{"key":"e_1_3_3_454_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.68.4.2260-2271.1994"},{"key":"e_1_3_3_455_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02333-14"},{"key":"e_1_3_3_456_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00611-15"},{"key":"e_1_3_3_457_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005141"},{"key":"e_1_3_3_458_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003299"},{"key":"e_1_3_3_459_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.02362"},{"key":"e_1_3_3_460_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000574"},{"key":"e_1_3_3_461_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.296772"},{"key":"e_1_3_3_462_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.058305"},{"key":"e_1_3_3_463_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002609"},{"key":"e_1_3_3_464_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00468-10"},{"key":"e_1_3_3_465_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003487"},{"key":"e_1_3_3_466_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1996.0130"},{"key":"e_1_3_3_467_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature06553"},{"key":"e_1_3_3_468_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2009.10.004"},{"key":"e_1_3_3_469_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2012.07.008"},{"key":"e_1_3_3_470_2","doi-asserted-by":"publisher","DOI":"10.2174\/157016212800792423"},{"key":"e_1_3_3_471_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1321507111"},{"key":"e_1_3_3_472_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00449-14"},{"key":"e_1_3_3_473_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-11-15"},{"key":"e_1_3_3_474_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep12256"},{"key":"e_1_3_3_475_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2014.10.002"},{"key":"e_1_3_3_476_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.01754"},{"key":"e_1_3_3_477_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01838-15"},{"key":"e_1_3_3_478_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00548-09"},{"key":"e_1_3_3_479_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03719-14"},{"key":"e_1_3_3_480_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.05788-11"},{"key":"e_1_3_3_481_2","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/ert401"},{"key":"e_1_3_3_482_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0473rev"},{"key":"e_1_3_3_483_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1997.8541"},{"key":"e_1_3_3_484_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1013177326481"},{"key":"e_1_3_3_485_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(98)00538-9"},{"key":"e_1_3_3_486_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(00)01971-2"},{"key":"e_1_3_3_487_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.6.5189-5197.1998"},{"key":"e_1_3_3_488_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1999.0094"},{"key":"e_1_3_3_489_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.2001.1166"},{"key":"e_1_3_3_490_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1997.8711"},{"key":"e_1_3_3_491_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.80.8.3765-3772.2006"},{"key":"e_1_3_3_492_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061388"},{"key":"e_1_3_3_493_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.15.7381"},{"key":"e_1_3_3_494_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0020039"},{"key":"e_1_3_3_495_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2007.08.009"},{"key":"e_1_3_3_496_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-2126(02)00720-7"},{"key":"e_1_3_3_497_2","doi-asserted-by":"publisher","DOI":"10.1002\/pro.2086"},{"key":"e_1_3_3_498_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1414063111"},{"key":"e_1_3_3_499_2","doi-asserted-by":"publisher","DOI":"10.2174\/1570162052772942"},{"key":"e_1_3_3_500_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10930-011-9316-2"},{"key":"e_1_3_3_501_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2009.10.008"},{"key":"e_1_3_3_502_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2005.04923.x"},{"key":"e_1_3_3_503_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12977-014-0079-7"},{"key":"e_1_3_3_504_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-10-126"},{"key":"e_1_3_3_505_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13062-014-0031-8"},{"key":"e_1_3_3_506_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-9-63"},{"key":"e_1_3_3_507_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.16.8477-8485.2004"},{"key":"e_1_3_3_508_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature07342"},{"key":"e_1_3_3_509_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.31.21539"},{"key":"e_1_3_3_510_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi972059x"},{"key":"e_1_3_3_511_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0127974"},{"key":"e_1_3_3_512_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.11.4776"},{"key":"e_1_3_3_513_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02353-07"},{"key":"e_1_3_3_514_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.81601-0"},{"key":"e_1_3_3_515_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-8-79"},{"key":"e_1_3_3_516_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2004.09.013"},{"key":"e_1_3_3_517_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-83-9-2225"},{"key":"e_1_3_3_518_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2004.09.029"},{"key":"e_1_3_3_519_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.71.8.5774-5781.1997"},{"key":"e_1_3_3_520_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(98)01602-0"},{"key":"e_1_3_3_521_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.23.13865"},{"key":"e_1_3_3_522_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1998.2585"},{"key":"e_1_3_3_523_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/25.9.1709"},{"key":"e_1_3_3_524_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0042-6822(95)80054-9"},{"key":"e_1_3_3_525_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2011.11.001"},{"key":"e_1_3_3_526_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2011.09.034"},{"key":"e_1_3_3_527_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2007.06.073"},{"key":"e_1_3_3_528_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2013.06.017"},{"key":"e_1_3_3_529_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(94)01370-G"},{"key":"e_1_3_3_530_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1997.8641"},{"key":"e_1_3_3_531_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.4.3178-3184.1998"},{"key":"e_1_3_3_532_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.71.2.1013-1018.1997"},{"key":"e_1_3_3_533_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.70.12.9051-9054.1996"},{"key":"e_1_3_3_534_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.11.8833-8840.1998"},{"key":"e_1_3_3_535_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1998.9407"},{"key":"e_1_3_3_536_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.6.2907-2912.2000"},{"key":"e_1_3_3_537_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.73.10.8824-8830.1999"},{"key":"e_1_3_3_538_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0095352"},{"key":"e_1_3_3_539_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0701443104"},{"key":"e_1_3_3_540_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02002-09"},{"key":"e_1_3_3_541_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-82-11-2719"},{"key":"e_1_3_3_542_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.13.6857-6862.2002"},{"key":"e_1_3_3_543_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.71.6.4372-4377.1997"},{"key":"e_1_3_3_544_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.10.5311-5323.2004"},{"key":"e_1_3_3_545_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(99)01791-3"},{"key":"e_1_3_3_546_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2009.01.042"},{"key":"e_1_3_3_547_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01633-08"},{"key":"e_1_3_3_548_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature15399"},{"key":"e_1_3_3_549_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.65.3.1325-1331.1991"},{"key":"e_1_3_3_550_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1286-4579(00)01256-9"},{"key":"e_1_3_3_551_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-80-11-2945"},{"key":"e_1_3_3_552_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.68.3.1714-1720.1994"},{"key":"e_1_3_3_553_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-8-11"},{"key":"e_1_3_3_554_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01522-15"},{"key":"e_1_3_3_555_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2424"},{"key":"e_1_3_3_556_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1877"},{"key":"e_1_3_3_557_2","first-page":"132","article-title":"2015 update of the drug resistance mutations in HIV-1","volume":"23","author":"Wensing AM","year":"2015","unstructured":"Wensing AM, Calvez V, Gunthard HF, Johnson VA, Paredes R, Pillay D, Shafer RW, Richman DD. 2015. 2015 update of the drug resistance mutations in HIV-1. Top Antivir Med 23:132\u2013141.","journal-title":"Top Antivir Med"},{"key":"e_1_3_3_558_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00695-14"},{"key":"e_1_3_3_559_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1004249"},{"key":"e_1_3_3_560_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2008.10.010"},{"key":"e_1_3_3_561_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.18.8358-8367.2000"},{"key":"e_1_3_3_562_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.18.8605-8614.2001"},{"key":"e_1_3_3_563_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-10-43"},{"key":"e_1_3_3_564_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0811713106"},{"key":"e_1_3_3_565_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2012.03.008"},{"key":"e_1_3_3_566_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2010.12.052"},{"key":"e_1_3_3_567_2","doi-asserted-by":"publisher","DOI":"10.3390\/v4123859"},{"key":"e_1_3_3_568_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0065631"},{"key":"e_1_3_3_569_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a007161"},{"key":"e_1_3_3_570_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2013.08.007"},{"key":"e_1_3_3_571_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01211-12"},{"key":"e_1_3_3_572_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20256"},{"key":"e_1_3_3_573_2","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.1853"},{"key":"e_1_3_3_574_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001073"},{"key":"e_1_3_3_575_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M414679200"},{"key":"e_1_3_3_576_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2006.07.022"},{"key":"e_1_3_3_577_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2006.12.007"},{"key":"e_1_3_3_578_2","doi-asserted-by":"publisher","DOI":"10.1021\/cb400495h"},{"key":"e_1_3_3_579_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm1003528"},{"key":"e_1_3_3_580_2","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20082068"},{"key":"e_1_3_3_581_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2006.03.015"},{"key":"e_1_3_3_582_2","doi-asserted-by":"publisher","DOI":"10.2174\/138161212802651634"},{"key":"e_1_3_3_583_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2011.05.024"},{"key":"e_1_3_3_584_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2012.09.001"},{"key":"e_1_3_3_585_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr717"},{"key":"e_1_3_3_586_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-7-114"},{"key":"e_1_3_3_587_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-011-0859-3"},{"key":"e_1_3_3_588_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2011.12.001"},{"key":"e_1_3_3_589_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1000377"},{"key":"e_1_3_3_590_2","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1177\/135965350400900115","article-title":"Susceptibility of HIV-2, SIV and SHIV to various anti-HIV-1 compounds: implications for treatment and postexposure prophylaxis","volume":"9","author":"Witvrouw M","year":"2004","unstructured":"Witvrouw M, Pannecouque C, Switzer WM, Folks TM, De Clercq E, Heneine W. 2004. Susceptibility of HIV-2, SIV and SHIV to various anti-HIV-1 compounds: implications for treatment and postexposure prophylaxis. Antivir Ther 9:57\u201365.","journal-title":"Antivir Ther"},{"key":"e_1_3_3_591_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2433165100"},{"key":"e_1_3_3_592_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.66.6.3306-3315.1992"},{"key":"e_1_3_3_593_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1996.8355"},{"key":"e_1_3_3_594_2","doi-asserted-by":"publisher","DOI":"10.1038\/12327"},{"key":"e_1_3_3_595_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.03.047"},{"key":"e_1_3_3_596_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0089116"},{"key":"e_1_3_3_597_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2015.05.010"},{"key":"e_1_3_3_598_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-5-84"},{"key":"e_1_3_3_599_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02765-12"},{"key":"e_1_3_3_600_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.280.5371.1884"},{"key":"e_1_3_3_601_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-10-54"},{"key":"e_1_3_3_602_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-385885-6.00010-9"},{"key":"e_1_3_3_603_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0854.2009.01006.x"},{"key":"e_1_3_3_604_2","doi-asserted-by":"publisher","DOI":"10.2174\/1570162X12666141202125643"},{"key":"e_1_3_3_605_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00042-05"},{"key":"e_1_3_3_606_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri1960"},{"key":"e_1_3_3_607_2","doi-asserted-by":"publisher","DOI":"10.1021\/ct4010307"},{"key":"e_1_3_3_608_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a007278"},{"key":"e_1_3_3_609_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2014.12.006"},{"key":"e_1_3_3_610_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.06359"},{"key":"e_1_3_3_611_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005289"},{"key":"e_1_3_3_612_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.188.11.2113"},{"key":"e_1_3_3_613_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.7.6004-6013.1998"},{"key":"e_1_3_3_614_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7601740"},{"key":"e_1_3_3_615_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M006130200"},{"key":"e_1_3_3_616_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(02)00556-9"},{"key":"e_1_3_3_617_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.2933"},{"key":"e_1_3_3_618_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/682850"},{"key":"e_1_3_3_619_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.74.7.3264-3272.2000"},{"key":"e_1_3_3_620_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.23.12699-12709.2003"},{"key":"e_1_3_3_621_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00049-13"},{"key":"e_1_3_3_622_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.15.6835-6840.2001"},{"key":"e_1_3_3_623_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1210983109"},{"key":"e_1_3_3_624_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.19.9156-9164.2001"},{"key":"e_1_3_3_625_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms6854"}],"container-title":["Microbiology and Molecular Biology Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/MMBR.00065-15","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/MMBR.00065-15","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,2]],"date-time":"2022-07-02T08:26:50Z","timestamp":1656750410000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/MMBR.00065-15"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":623,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1128\/MMBR.00065-15"],"URL":"https:\/\/doi.org\/10.1128\/mmbr.00065-15","relation":{},"ISSN":["1092-2172","1098-5557"],"issn-type":[{"value":"1092-2172","type":"print"},{"value":"1098-5557","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"2016-06-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}