{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:45:20Z","timestamp":1790210720044,"version":"4.1.0"},"reference-count":223,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Canadian Government | Natural Sciences and Engineering Research Council of Canada","award":["RGPIN-2020-03886"],"award-info":[{"award-number":["RGPIN-2020-03886"]}]},{"name":"DHAC | National Health and Medical Research Council","award":["APP1176192"],"award-info":[{"award-number":["APP1176192"]}]},{"DOI":"10.13039\/501100001804","name":"Canada Research Chairs","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001804","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Microbiol Mol Biol Rev"],"published-print":{"date-parts":[[2025,6,25]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                    is a gram-negative species, whose isolates are found in the environment and as commensals in the human gastrointestinal tract. This bacterium is among the leading causes of a range of nosocomial and community-acquired infections, particularly in immunocompromised individuals, where it can give rise to pneumonia, urinary tract infections, septicemia, and liver abscesses. Treatment of\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    infections is compromised by the emergence of isolates producing carbapenemase and extended-spectrum \u03b2-lactamase enzymes, making it a high priority for new therapeutic approaches including vaccination and immunoprophylaxis. One potential target for these strategies is the O-antigen polysaccharide component of lipopolysaccharides, which are important virulence determinants for\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    . Consideration of immunotherapeutic opportunities requires a comprehensive and fundamental understanding of O-polysaccharide structures, distribution of particular O serotypes in clinical isolates, and the potential for antigenic diversification. The number of recognized\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    O-polysaccharide antigens has varied over time, complicated by the observation that some examples share similar structural (and potentially antigenically cross-reactive) elements, and by the existence of genetic loci for which corresponding O-polysaccharide structures have yet to be determined. Here, we provide a comprehensive integration of the current carbohydrate structures and genetic information, together with a proposal for an updated classification system for\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    O-antigens, that is being implemented in Kaptive for molecular serotyping. The accumulated insight into O-polysaccharide assembly pathways is used to describe the molecular basis for O-antigen diversity in\n                    <jats:italic toggle=\"yes\">K. pneumoniae<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1128\/mmbr.00090-23","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T09:53:26Z","timestamp":1742550806000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":19,"title":["O-antigen polysaccharides in\n                    <i>Klebsiella pneumoniae<\/i>\n                    : structures and molecular basis for antigenic diversity"],"prefix":"10.1128","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5267-7027","authenticated-orcid":true,"given":"Chris","family":"Whitfield","sequence":"first","affiliation":[{"name":"Department of Molecular and Cellular Biology, University of Guelph","place":["Guelph, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1250-7055","authenticated-orcid":false,"given":"Steven D.","family":"Kelly","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Biology, University of Guelph","place":["Guelph, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom D.","family":"Stanton","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, School of Translational Medicine, Monash University","place":["Melbourne, Australia"]},{"name":"Centre to Impact AMR, Monash University","place":["Clayton, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4033-6639","authenticated-orcid":true,"given":"Kelly L.","family":"Wyres","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, School of Translational Medicine, Monash University","place":["Melbourne, Australia"]},{"name":"Centre to Impact AMR, Monash University","place":["Clayton, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2233-1268","authenticated-orcid":true,"given":"Bradley R.","family":"Clarke","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Biology, University of Guelph","place":["Guelph, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor J. B.","family":"Forrester","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Biology, University of Guelph","place":["Guelph, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Kowalczyk","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Biology, University of Guelph","place":["Guelph, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00078-15"},{"key":"e_1_3_3_3_2","first-page":"159","volume-title":"The prokaryotes","author":"Briss\u00e9 S","year":"2013","unstructured":"Briss\u00e9 S, Grimont F, Grimont P. 2013. The genus Klebsiella, p 159\u2013196. In The prokaryotes, 4th ed. Springer, Berlin, Heidelberg, Dordrecht, New York.","edition":"4"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1501049112"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-019-0315-1"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-51-3-915"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-51-3-925"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-30717-6"},{"key":"e_1_3_3_9_2","first-page":"2221","article-title":"Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019","volume":"400","author":"GBD 2019 Antimicrobial Resistance Collaborators","year":"2023","unstructured":"GBD 2019 Antimicrobial Resistance Collaborators. 2023. Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 400:2221\u20132248.","journal-title":"Lancet"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02724-0"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-024-01054-w"},{"key":"e_1_3_3_12_2","unstructured":"Organization WH2024. WHO Bacterial Priority Pathogens List 2024: bacterial pathogens of public health importance to guide research development and strategies to prevent and control antimicrobial resistance."},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-24448-3"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-28199-y"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.11.4.589"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00001-19"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2024.105331"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-51213-z"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/msphere.00464-23"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2024.105302"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000102"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00197-18"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000800"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciab784"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.00800-23"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20030857"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.185.19.5882-5890.2003"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2013.03.010"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.28611-0"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01517-21"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0580-9517(08)70449-5"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv840"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep15573"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.3390\/biology13040256"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1508820112"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1033.2001.02047.x"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6215(01)00216-6"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.187.12.4198-4206.2005"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M504987200"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwv091"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M202683200"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.173.4.1420-1431.1991"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/0008-6215(91)84122-u"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/0008-6215(92)85028-X"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2301302120"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.174.15.4913-4919.1992"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1177\/096805199500200208"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.00684"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1993.tb00933.x"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.3891\/acta.chem.scand.27-2645"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2011.11.019"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-06682-2"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2024.107420"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.3891\/acta.chem.scand.26-1269"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.3891\/acta.chem.scand.26-2231"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.3891\/acta.chem.scand.24-3414"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA119.008969"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1613609114"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6215(00)83359-5"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2023.121581"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1949.tb00741.x"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1954.tb00811.x"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1128\/cdli.4.5.550-555.1997"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.1.56-62.1999"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000073"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1997.tb01887.x"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-024-01342-3"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-021-05790-9"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1954.tb00811.x"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2015.12.002"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-52372-9"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-44-1-44"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2008.00396.x"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6976.12034"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/0008-6215(89)84041-8"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/0008-6215(89)85122-5"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.178.1.317-320.1996"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18122572"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1016\/0008-6215(89)85094-3"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1016\/0008-6215(93)84231-T"},{"key":"e_1_3_3_81_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.1996.tb08138.x"},{"key":"e_1_3_3_82_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1976.tb10631.x"},{"key":"e_1_3_3_83_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6215(00)90158-7"},{"key":"e_1_3_3_84_2","first-page":"199","article-title":"Structure of the determinant group of the O-specific polysaccharide of Escherichia coli O20:K84:H34(145)","volume":"2","author":"Vasiliev VN","year":"1976","unstructured":"Vasiliev VN, Z IY. 1976. Structure of the determinant group of the O-specific polysaccharide of Escherichia coli O20:K84:H34(145). Bioorg Khim 2:199\u2013206.","journal-title":"Bioorg Khim"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0008-6215(00)90412-9"},{"key":"e_1_3_3_86_2","doi-asserted-by":"publisher","DOI":"10.1016\/0008-6215(95)00095-b"},{"key":"e_1_3_3_87_2","doi-asserted-by":"publisher","DOI":"10.1177\/1753425909350057"},{"key":"e_1_3_3_88_2","doi-asserted-by":"publisher","DOI":"10.3390\/md13042233"},{"key":"e_1_3_3_89_2","doi-asserted-by":"publisher","DOI":"10.1016\/0008-6215(91)80170-r"},{"key":"e_1_3_3_90_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.1994.tb06638.x"},{"key":"e_1_3_3_91_2","doi-asserted-by":"publisher","DOI":"10.1016\/0008-6215(91)84104-M"},{"key":"e_1_3_3_92_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-50957-y"},{"key":"e_1_3_3_93_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1996.0786p.x"},{"key":"e_1_3_3_94_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M404738200"},{"key":"e_1_3_3_95_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.14447"},{"key":"e_1_3_3_96_2","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2024.2439509"},{"key":"e_1_3_3_97_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-129-7-2181"},{"key":"e_1_3_3_98_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.62.10.4495-4499.1994"},{"key":"e_1_3_3_99_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01713568"},{"key":"e_1_3_3_100_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1996.tb52974.x"},{"key":"e_1_3_3_101_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.2.664-669.1999"},{"key":"e_1_3_3_102_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.5.2583-2590.2002"},{"key":"e_1_3_3_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2004.06.003"},{"key":"e_1_3_3_104_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00864-09"},{"key":"e_1_3_3_105_2","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2021.1960101"},{"key":"e_1_3_3_106_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2400446121"},{"key":"e_1_3_3_107_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.621292"},{"key":"e_1_3_3_108_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01733-20"},{"key":"e_1_3_3_109_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2022.111167"},{"key":"e_1_3_3_110_2","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.202216888"},{"key":"e_1_3_3_111_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.12.7107-7114.2004"},{"key":"e_1_3_3_112_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00129-06"},{"key":"e_1_3_3_113_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0825-4"},{"key":"e_1_3_3_114_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1238482"},{"key":"e_1_3_3_115_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-46147-5"},{"key":"e_1_3_3_116_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.3.1423-1430.2004"},{"key":"e_1_3_3_117_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13099-016-0085-5"},{"key":"e_1_3_3_118_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.54.1.85-89.1986"},{"key":"e_1_3_3_119_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.55.11.2741-2746.1987"},{"key":"e_1_3_3_120_2","doi-asserted-by":"publisher","DOI":"10.1139\/m89-166"},{"key":"e_1_3_3_121_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.57.12.3816-3822.1989"},{"key":"e_1_3_3_122_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.60.6.2529-2535.1992"},{"key":"e_1_3_3_123_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.61.3.852-860.1993"},{"key":"e_1_3_3_124_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.88971.1"},{"key":"e_1_3_3_125_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.64.11.4726-4732.1996"},{"key":"e_1_3_3_126_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-71487-z"},{"key":"e_1_3_3_127_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1010051"},{"key":"e_1_3_3_128_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.2.953-955.2000"},{"key":"e_1_3_3_129_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00043-20"},{"key":"e_1_3_3_130_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.REV120.009402"},{"key":"e_1_3_3_131_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2019.02.003"},{"key":"e_1_3_3_132_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-02223-7"},{"key":"e_1_3_3_133_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1108472"},{"key":"e_1_3_3_134_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.741256"},{"key":"e_1_3_3_135_2","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1525"},{"key":"e_1_3_3_136_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2022.101704"},{"key":"e_1_3_3_137_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2022.104482"},{"key":"e_1_3_3_138_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fuy011"},{"key":"e_1_3_3_139_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22084042"},{"key":"e_1_3_3_140_2","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2019.1635460"},{"key":"e_1_3_3_141_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2023.08.005"},{"key":"e_1_3_3_142_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2024.02.072"},{"key":"e_1_3_3_143_2","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2019.1657012"},{"key":"e_1_3_3_144_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiae097"},{"key":"e_1_3_3_145_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1907833116"},{"key":"e_1_3_3_146_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.45.1.139-142.1984"},{"key":"e_1_3_3_147_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/150.6.817"},{"key":"e_1_3_3_148_2","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410x(86)90092-7"},{"key":"e_1_3_3_149_2","doi-asserted-by":"publisher","DOI":"10.1016\/0882-4010(88)90020-4"},{"key":"e_1_3_3_150_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.26.11.2257-2261.1988"},{"key":"e_1_3_3_151_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00091-18"},{"key":"e_1_3_3_152_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00297-18"},{"key":"e_1_3_3_153_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02994-19"},{"key":"e_1_3_3_154_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.0c01404"},{"key":"e_1_3_3_155_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.843183"},{"key":"e_1_3_3_156_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0928-8244(02)00459-5"},{"key":"e_1_3_3_157_2","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.gpp3-0028-2018"},{"key":"e_1_3_3_158_2","doi-asserted-by":"publisher","unstructured":"Hwang W Wantuch PL Bernshtein B Zhiteneva J Slater D Vater KH Sridhar S Oliver E Roach DJ Rao S Turbett SE Knoot CJ Harding CM Amin MN Cross AS LaRocque RC Rosen DA Harris JB. 2024. Antibody responses in Klebsiella pneumoniae bloodstream infection: a cohort study. bioRxiv:2024.05.01.591958. doi:10.1101\/2024.05.01.591958","DOI":"10.1101\/2024.05.01.591958"},{"key":"e_1_3_3_159_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02494-15"},{"key":"e_1_3_3_160_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.01249"},{"key":"e_1_3_3_161_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-022-07558-1"},{"key":"e_1_3_3_162_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-018-0106-2"},{"key":"e_1_3_3_163_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.07.100"},{"key":"e_1_3_3_164_2","doi-asserted-by":"publisher","DOI":"10.1128\/msphere.00680-22"},{"key":"e_1_3_3_165_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0203143"},{"key":"e_1_3_3_166_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.58.5.1421-1428.1990"},{"key":"e_1_3_3_167_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.59.6.2006-2011.1991"},{"key":"e_1_3_3_168_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.5.2402-2409.2000"},{"key":"e_1_3_3_169_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1011367"},{"key":"e_1_3_3_170_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.65.5.1754-1760.1997"},{"key":"e_1_3_3_171_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2024.126536"},{"key":"e_1_3_3_172_2","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.92774"},{"key":"e_1_3_3_173_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-060713-035600"},{"key":"e_1_3_3_174_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3047"},{"key":"e_1_3_3_175_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c00587"},{"key":"e_1_3_3_176_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-06709-x"},{"key":"e_1_3_3_177_2","doi-asserted-by":"publisher","DOI":"10.1042\/BST20200762"},{"key":"e_1_3_3_178_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01914-20"},{"key":"e_1_3_3_179_2","doi-asserted-by":"publisher","DOI":"10.1002\/1873-3468.13935"},{"key":"e_1_3_3_180_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-04555-x"},{"key":"e_1_3_3_181_2","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwr150"},{"key":"e_1_3_3_182_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0378-1119(97)00300-4"},{"key":"e_1_3_3_183_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.177.8.2178-2187.1995"},{"key":"e_1_3_3_184_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.2935"},{"key":"e_1_3_3_185_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.052878"},{"key":"e_1_3_3_186_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.401000"},{"key":"e_1_3_3_187_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.622480"},{"key":"e_1_3_3_188_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab1045"},{"key":"e_1_3_3_189_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1998.00765.x"},{"key":"e_1_3_3_190_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)83524-4"},{"key":"e_1_3_3_191_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi802284d"},{"key":"e_1_3_3_192_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-02880-2"},{"key":"e_1_3_3_193_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.171.7.3629-3633.1989"},{"key":"e_1_3_3_194_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.412577"},{"key":"e_1_3_3_195_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.295857"},{"key":"e_1_3_3_196_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1400814111"},{"key":"e_1_3_3_197_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.12014"},{"key":"e_1_3_3_198_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M504371200"},{"key":"e_1_3_3_199_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0705709104"},{"key":"e_1_3_3_200_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-32597-2"},{"key":"e_1_3_3_201_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature25190"},{"key":"e_1_3_3_202_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-08646-8"},{"key":"e_1_3_3_203_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2016144118"},{"key":"e_1_3_3_204_2","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwz066"},{"key":"e_1_3_3_205_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1603146113"},{"key":"e_1_3_3_206_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.7.4121"},{"key":"e_1_3_3_207_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsb1001-858"},{"key":"e_1_3_3_208_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.122598"},{"key":"e_1_3_3_209_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-020-0494-0"},{"key":"e_1_3_3_210_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0966-842x(99)01646-7"},{"key":"e_1_3_3_211_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01393-13"},{"key":"e_1_3_3_212_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA117.000646"},{"key":"e_1_3_3_213_2","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwad053"},{"key":"e_1_3_3_214_2","doi-asserted-by":"publisher","DOI":"10.1139\/cjc-2015-0594"},{"key":"e_1_3_3_215_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M807213200"},{"key":"e_1_3_3_216_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA119.010323"},{"key":"e_1_3_3_217_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2014.00608"},{"key":"e_1_3_3_218_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1008114"},{"key":"e_1_3_3_219_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2018.06.006"},{"key":"e_1_3_3_220_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21186572"},{"key":"e_1_3_3_221_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-33988-1"},{"key":"e_1_3_3_222_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.4c02073"},{"key":"e_1_3_3_223_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-022-01006-6"},{"key":"e_1_3_3_224_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2402554121"}],"container-title":["Microbiology and Molecular Biology Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mmbr.00090-23","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mmbr.00090-23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:46:53Z","timestamp":1756306013000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mmbr.00090-23"}},"subtitle":[],"editor":[{"given":"Corrella S.","family":"Detweiler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,6,25]]},"references-count":223,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,6,25]]}},"alternative-id":["10.1128\/mmbr.00090-23"],"URL":"https:\/\/doi.org\/10.1128\/mmbr.00090-23","relation":{},"ISSN":["1092-2172","1098-5557"],"issn-type":[{"value":"1092-2172","type":"print"},{"value":"1098-5557","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,25]]},"assertion":[{"value":"2025-03-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00090-23"}}