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These infections are frequently associated with high mortality rates, often exceeding 50%, even with antifungal therapy.\n                    <jats:italic toggle=\"yes\">Candida auris<\/jats:italic>\n                    is a multidrug-resistant fungal pathogen that has a unique ability to grow and persist on human skin. Long-term skin colonization by\n                    <jats:italic toggle=\"yes\">C. auris<\/jats:italic>\n                    is a significant medical concern because colonized patients may facilitate inter- and intra-hospital transmission of\n                    <jats:italic toggle=\"yes\">C. auris<\/jats:italic>\n                    to other patients. Furthermore,\n                    <jats:italic toggle=\"yes\">C. auris<\/jats:italic>\n                    -colonized patients are at risk of developing more serious systemic infections. The diagnosis of\n                    <jats:italic toggle=\"yes\">C. auris<\/jats:italic>\n                    infections is often hampered by misidentification, leading to delays in starting appropriate antifungal therapy. Here, we summarize the global burden of candidiasis due to\n                    <jats:italic toggle=\"yes\">C. auris<\/jats:italic>\n                    , antifungal drug resistance mechanisms, host and fungal factors affecting skin colonization, current diagnostic approaches, as well as current and future challenges to combat the spread of invasive fungal infections.\n                  <\/jats:p>","DOI":"10.1128\/mmbr.00187-22","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T14:00:40Z","timestamp":1764770440000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":15,"title":["<i>Candida auris<\/i>\n                    : host interactions, antifungal drug resistance, and diagnostics"],"prefix":"10.1128","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2028-7462","authenticated-orcid":true,"given":"Anuradha","family":"Chowdhary","sequence":"first","affiliation":[{"name":"Medical Mycology Unit, Department of Microbiology, and the National Reference Laboratory for Antimicrobial Resistance in Fungal Pathogens, Vallabhbhai Patel Chest Institute, University of Delhi","place":["New Delhi, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4994-9500","authenticated-orcid":true,"given":"Michail S.","family":"Lionakis","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01cwqze88","id-type":"ROR","asserted-by":"publisher"}],"name":"Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health","place":["Bethesda, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9252-9897","authenticated-orcid":true,"given":"Neeraj","family":"Chauhan","sequence":"additional","affiliation":[{"name":"Center for Discovery and Innovation, Hackensack Meridian Health","place":["Nutley, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(23)00692-8"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3004404"},{"key":"e_1_3_2_4_2","unstructured":"WHO. 2022. 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