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Though\n                    <jats:italic toggle=\"yes\">Candida<\/jats:italic>\n                    now represents a lower proportion of cases than in the past,\n                    <jats:italic toggle=\"yes\">Candida albicans<\/jats:italic>\n                    remains the most prevalent species in human infections, and disseminated candidiasis remains associated with an unacceptably high mortality rate in immunocompromised patients. Most individuals are protected by the innate immune system, of which phagocytes are a key mediator. The complex dynamic between\n                    <jats:italic toggle=\"yes\">C. albicans<\/jats:italic>\n                    and macrophages has become an important model system for host-pathogen interactions in which both sides engage in intricate developmental programs to respond to the other. In this review, we discuss the molecular mechanisms of recognition and response with a focus on\n                    <jats:italic toggle=\"yes\">C. albicans<\/jats:italic>\n                    , but including other\n                    <jats:italic toggle=\"yes\">Candida<\/jats:italic>\n                    species, with an eye toward therapeutic interventions to improve patient outcomes.\n                  <\/jats:p>","DOI":"10.1128\/mmbr.00191-22","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T13:00:56Z","timestamp":1789390856000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["From confrontation to co-adaptation: the dynamic dialogue of\n                    <i>Candida albicans<\/i>\n                    and macrophages"],"prefix":"10.1128","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6867-7697","authenticated-orcid":true,"given":"Pedro","family":"Miram\u00f3n","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03gds6c39","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Microbiology and Molecular Genetics, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth Houston)","place":["Houston, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah B.","family":"Wilson","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03gds6c39","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Microbiology and Molecular Genetics, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth Houston)","place":["Houston, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7881-8027","authenticated-orcid":true,"given":"Michael C.","family":"Lorenz","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03gds6c39","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Microbiology and Molecular Genetics, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth Houston)","place":["Houston, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","published-online":{"date-parts":[[2026,9,14]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(23)00692-8"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-023-00861-x"},{"key":"e_1_3_2_4_2","first-page":"1","volume-title":"WHO Fungal Priority Pathogens List to Guide Research, Development and Public Health Action","author":"World Health Organization","year":"2022","unstructured":"World Health Organization. 2022. 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