{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:46:25Z","timestamp":1791812785749,"version":"4.3.4"},"reference-count":165,"publisher":"American Society for Microbiology","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R35GM136213"],"award-info":[{"award-number":["R35GM136213"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["5T32AI089621"],"award-info":[{"award-number":["5T32AI089621"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Microbiol Mol Biol Rev"],"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    Translational fidelity is maintained throughout evolution and ensures the accurate flow of genetic information from mRNA to protein. Both aminoacyl-tRNA synthetases and ribosomes use substrate selection and proofreading to lower translational errors. However, genetic mutations and environmental changes frequently alter translational fidelity. Recent technological advances have enabled sensitive detection of translational errors and high-throughput screening of conditions that alter translational fidelity. With a focus on\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">Salmonella enterica<\/jats:italic>\n                    , this article reviews the methods used to quantitate translational errors\n                    <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                    , the impact of various stresses and metabolic changes on translational fidelity, and the effects of altered translational fidelity on evolution, stress adaptation, and bacteria-host interactions.\n                  <\/jats:p>","DOI":"10.1128\/mmbr.00337-25","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:00:59Z","timestamp":1791810059000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["Fidelity during bacterial protein 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