{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T03:10:19Z","timestamp":1791947419694,"version":"4.3.4"},"reference-count":20,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T00:00:00Z","timestamp":1583884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,4,29]],"date-time":"2020-04-29T00:00:00Z","timestamp":1588118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100000867","name":"Commonwealth Scholarship Commission","doi-asserted-by":"publisher","award":["BDCS-2016-53"],"award-info":[{"award-number":["BDCS-2016-53"]}],"id":[{"id":"10.13039\/501100000867","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mSphere"],"published-print":{"date-parts":[[2020,4,29]]},"abstract":"<jats:p>\n            There is a marked paucity in our understanding of the epidemiology of colistin-resistant bacterial pathogens in South Asia. A report by Davies and Walsh (Lancet Infect Dis 18:256\u2013257,\n            <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/doi.org\/10.1016\/S1473-3099(18)30072-0\">https:\/\/doi.org\/10.1016\/S1473-3099(18)30072-0<\/jats:ext-link>\n            , 2018) suggests the export of colistin from China to India, Vietnam, and South Korea in 2016 was approximately 1,000 tons and mainly used as a poultry feed additive. A few reports forecast that the prevalence of\n            <jats:italic>mcr<\/jats:italic>\n            in humans and livestock will increase in South Asia. Given the high prevalence of\n            <jats:italic>bla<\/jats:italic>\n            <jats:sub>CTX-M-15<\/jats:sub>\n            and\n            <jats:italic>bla<\/jats:italic>\n            <jats:sub>NDM<\/jats:sub>\n            in India, Bangladesh, and Pakistan, colistin has become the invariable option for the management of serious infections, leading to the emergence of\n            <jats:italic>mcr<\/jats:italic>\n            -like mechanisms in South Asia. Systematic scrutiny of the prevalence and transmission of\n            <jats:italic>mcr<\/jats:italic>\n            variants in South Asia is vital to understanding the drivers of\n            <jats:italic>mcr<\/jats:italic>\n            genes and to initiate interventions to overcome colistin resistance.\n          <\/jats:p>","DOI":"10.1128\/msphere.00023-20","type":"journal-article","created":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T10:22:14Z","timestamp":1583922134000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":43,"title":["Emergence of Mobile Colistin Resistance (\n            <i>mcr-8<\/i>\n            ) in a Highly Successful Klebsiella pneumoniae Sequence Type 15 Clone from Clinical Infections in Bangladesh"],"prefix":"10.1128","volume":"5","author":[{"given":"Refath","family":"Farzana","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lim S.","family":"Jones","sequence":"additional","affiliation":[{"name":"Public Health Wales Microbiology, University Hospital of Wales, Cardiff, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Barratt","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Anisur","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Virology, Dhaka Medical College, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsty","family":"Sands","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Portal","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Boostrom","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Espina","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monira","family":"Pervin","sequence":"additional","affiliation":[{"name":"Department of Virology, Dhaka Medical College, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. K. M. Nasir","family":"Uddin","sequence":"additional","affiliation":[{"name":"Dhaka Medical College Hospital, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy R.","family":"Walsh","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2018.00004"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2019.07.019"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-016-0115-6"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30072-0"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgar.2018.09.005"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2018.1462060"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13099-017-0227-4"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.2217\/fmb-2019-0053"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.11541"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-015-2453-3"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2014.00643"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00424-7"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(16)30527-8"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41426-018-0124-z"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01021"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-02149-0"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-04662-0"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy778"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/335351a0"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-12-53"}],"container-title":["mSphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSphere.00023-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSphere.00023-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T04:37:22Z","timestamp":1646714242000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mSphere.00023-20"}},"subtitle":[],"editor":[{"given":"Ana Cristina","family":"Gales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,4,29]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,4,29]]}},"alternative-id":["10.1128\/mSphere.00023-20"],"URL":"https:\/\/doi.org\/10.1128\/msphere.00023-20","relation":{},"ISSN":["2379-5042"],"issn-type":[{"value":"2379-5042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,29]]},"assertion":[{"value":"2020-01-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00023-20"}}