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However, researchers rarely compare such strains to elucidate the underlying mutation(s). In this study, we tested one of the best-studied\n            <jats:named-content content-type=\"genus-species\">V. cholerae<\/jats:named-content>\n            isolates, O1 El Tor strain C6706 (a patient isolate from Peru), with respect to two main phenotypes: natural competence for transformation and type VI secretion. We recently demonstrated that the two phenotypes are coregulated and specifically induced upon the growth of pandemic\n            <jats:named-content content-type=\"genus-species\">V. cholerae<\/jats:named-content>\n            O1 El Tor strains on chitinous surfaces. We provide evidence that of seven C6706 strains collected from different laboratories, four were impaired in the tested phenotypes due to a mutation in a QS gene. Collectively, our data indicate that the circulation of such a mutated wild-type strain of C6706 might have had important consequences for QS-related data.\n          <\/jats:p>","DOI":"10.1128\/msphere.00098-16","type":"journal-article","created":{"date-parts":[[2016,5,26]],"date-time":"2016-05-26T03:34:19Z","timestamp":1464233659000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":35,"title":["Circulation of a Quorum-Sensing-Impaired Variant of Vibrio cholerae Strain C6706 Masks Important Phenotypes"],"prefix":"10.1128","volume":"1","author":[{"given":"Sandrine","family":"Stutzmann","sequence":"first","affiliation":[{"name":"Laboratory of Molecular Microbiology, Global Health Institute, School of Life Sciences, \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne (EPFL), Lausanne, 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