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In phase 1 studies, a\n            <jats:named-content content-type=\"genus-species\">C. jejuni<\/jats:named-content>\n            capsule conjugate vaccine was safe but poorly immunogenic when delivered alone or with aluminum hydroxide. Here, we report enhanced immunogenicity of the conjugate vaccine delivered with liposome adjuvants containing monophosphoryl lipid A without or with QS-21, known as ALF and ALFQ, respectively, in preclinical studies. Both liposome adjuvants significantly enhanced immunity in mice and nonhuman primates and improved protective efficacy of the vaccine compared to alum in a nonhuman primate\n            <jats:named-content content-type=\"genus-species\">C. jejuni<\/jats:named-content>\n            diarrhea model, providing promising evidence that these potent adjuvant formulations may enhance immunogenicity in upcoming human studies with this\n            <jats:named-content content-type=\"genus-species\">C. jejuni<\/jats:named-content>\n            conjugate and other malaria and HIV vaccine platforms.\n          <\/jats:p>","DOI":"10.1128\/msphere.00101-19","type":"journal-article","created":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T12:58:22Z","timestamp":1556629102000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":6,"title":["Enhanced Immunogenicity and Protective Efficacy of a\n            <i>Campylobacter jejuni<\/i>\n            Conjugate Vaccine Coadministered with Liposomes Containing Monophosphoryl Lipid A and QS-21"],"prefix":"10.1128","volume":"4","author":[{"given":"Amritha","family":"Ramakrishnan","sequence":"first","affiliation":[{"name":"Bacteriology Department, U.S. Naval Medical Research Unit No. 6, Callao, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina M.","family":"Schumack","sequence":"additional","affiliation":[{"name":"Henry M. 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