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Of the infections by bacteria able to colonize such injuries, those by\n            <jats:named-content content-type=\"genus-species\">Pseudomonas aeruginosa<\/jats:named-content>\n            are among the most severe, causing major delays in burn patient recovery or leading to fatal issues. In this study, we investigated the growth properties of several burn wound pathogens in biological fluids secreted from human burn wounds. We found that\n            <jats:named-content content-type=\"genus-species\">P. aeruginosa<\/jats:named-content>\n            strains were able to proliferate but not those of the other pathogens tested. In addition, burn wound exudates (BWEs) stimulate the expression of virulence factors in\n            <jats:named-content content-type=\"genus-species\">P. aeruginosa<\/jats:named-content>\n            . The chemical composition analysis of BWEs enabled us to determine the major components of these fluids. These data are essential for the development of an artificial medium mimicking the burn wound environment and for\n            <jats:italic>in vitro<\/jats:italic>\n            analysis of the initial step in the development of burn wound infections.\n          <\/jats:p>","DOI":"10.1128\/msphere.00111-15","type":"journal-article","created":{"date-parts":[[2016,4,28]],"date-time":"2016-04-28T03:32:53Z","timestamp":1461814373000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":78,"title":["Effect of Human Burn Wound Exudate on Pseudomonas aeruginosa Virulence"],"prefix":"10.1128","volume":"1","author":[{"given":"Manuel R.","family":"Gonzalez","sequence":"first","affiliation":[{"name":"Microbiology Unit, Department of Botany and Plant Biology, Sciences III, University of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betty","family":"Fleuchot","sequence":"additional","affiliation":[{"name":"Microbiology Unit, Department of Botany and Plant Biology, Sciences III, University of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Lauciello","sequence":"additional","affiliation":[{"name":"Microbiology Unit, Department of Botany and Plant Biology, Sciences III, University of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paris","family":"Jafari","sequence":"additional","affiliation":[{"name":"Plastic, Reconstructive &amp; Hand Surgery, Unit of Regenerative Therapy, Lausanne University Hospital, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee Ann","family":"Applegate","sequence":"additional","affiliation":[{"name":"Plastic, Reconstructive &amp; Hand Surgery, Unit of Regenerative Therapy, Lausanne University Hospital, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wassim","family":"Raffoul","sequence":"additional","affiliation":[{"name":"Plastic, Reconstructive &amp; Hand Surgery, Unit of Regenerative Therapy, Lausanne University Hospital, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yok-Ai","family":"Que","sequence":"additional","affiliation":[{"name":"Service of Adult Intensive Care Medicine &amp; Burns, Lausanne University Hospital, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Perron","sequence":"additional","affiliation":[{"name":"Microbiology Unit, Department of Botany and Plant Biology, Sciences III, University of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2011.00269.x"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M312080200"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080140"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002192"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.184.10.2576-2586.2002"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/549302"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/35037627"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13684"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2007.11.017"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep09936"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2015.10.030"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2006.00159.x"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.19.2.403-434.2006"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16360-5"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2005.04.026"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/85.5.1293"},{"key":"e_1_3_2_18_2","doi-asserted-by":"crossref","unstructured":"Cutting\nKF\n. 2003. 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