{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T01:43:36Z","timestamp":1776303816221,"version":"3.50.1"},"reference-count":25,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2019,6,12]],"date-time":"2019-06-12T00:00:00Z","timestamp":1560297600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T00:00:00Z","timestamp":1561507200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mSphere"],"published-print":{"date-parts":[[2019,6,26]]},"abstract":"<jats:p>\n            The progressive rise in antibiotic resistance among enteric pathogens in developing countries is becoming a big concern. India is one of the largest consumers of antibiotics, and their use is not well regulated.\n            <jats:named-content content-type=\"genus-species\">V. fluvialis<\/jats:named-content>\n            is increasingly recognized as an emerging diarrheal pathogen of public health importance. Here we report the emergence of azithromycin resistance in\n            <jats:named-content content-type=\"genus-species\">V. fluvialis<\/jats:named-content>\n            isolates from diarrheal patients in Kolkata, India. Azithromycin has been widely used in the treatment of various infections, both in children and in adults. Resistance to azithromycin is encoded in the gene\n            <jats:italic>mph<\/jats:italic>\n            (A). Emerging azithromycin resistance in\n            <jats:named-content content-type=\"genus-species\">V. fluvialis<\/jats:named-content>\n            is a major public health challenge, and future studies should be focused on identifying ways to prevent the dissemination of this antibiotic resistance gene.\n          <\/jats:p>","DOI":"10.1128\/msphere.00215-19","type":"journal-article","created":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T15:42:25Z","timestamp":1560267745000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":21,"title":["Emergence of Azithromycin Resistance Mediated by Phosphotransferase-Encoding\n            <i>mph<\/i>\n            (A) in Diarrheagenic Vibrio fluvialis"],"prefix":"10.1128","volume":"4","author":[{"given":"Goutam","family":"Chowdhury","sequence":"first","affiliation":[{"name":"Department of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thandavarayan","family":"Ramamurthy","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India"},{"name":"Translational Health Science and Technology Institute, Faridabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shanta","family":"Dutta","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eizo","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Collaborative Research Center of Okayama University for Infectious Diseases at ICMR-NICED, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asish K.","family":"Mukhopadhyay","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph7103628"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/1757-4749-5-6"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2013.1491"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1811.120520"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h6420"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2014.00091"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2011.04.013"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2210.151612"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2013.05.012"},{"key":"e_1_3_2_11_2","first-page":"645","volume-title":"Red book: report of the Committee on Infectious Diseases","author":"Committee on Infectious Diseases, American Academy of Pediatrics","year":"2012","unstructured":"Committee on Infectious Diseases, American Academy of Pediatrics. 2012. Red book: report of the Committee on Infectious Diseases, 29th ed, p 645\u2013647. American Academy of Pediatrics, Elk Grove Village, IL.","edition":"29"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1086\/318514"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1510.090696"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw318"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01748-17"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01561-05"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2009.03.020"},{"key":"e_1_3_2_18_2","unstructured":"WHO. 2014. Antimicrobial resistance: global report on surveillance p 257. WHO Geneva Switzerland. http:\/\/www.who.int\/drugresistance\/documents\/surveillancereport\/en\/."},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.023051-0"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2005.130966"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.3109\/1040841X.2015.1136261"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2013.07.016"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.14.4.933-951.2001"},{"key":"e_1_3_2_24_2","volume-title":"Performance standards for antimicrobial susceptibility testing","author":"Clinical and Laboratory Standards Institute","year":"2016","unstructured":"Clinical and Laboratory Standards Institute. 2016. Performance standards for antimicrobial susceptibility testing, 26th ed. CLSI supplement M100S. Clinical and Laboratory Standards Institute, Wayne, PA.","edition":"26"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.10.3214-3221.2003"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2006.3.51"}],"container-title":["mSphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSphere.00215-19","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSphere.00215-19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T04:19:30Z","timestamp":1646713170000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mSphere.00215-19"}},"subtitle":[],"editor":[{"given":"Mariana","family":"Castanheira","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2019,6,26]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,6,26]]}},"alternative-id":["10.1128\/mSphere.00215-19"],"URL":"https:\/\/doi.org\/10.1128\/msphere.00215-19","relation":{},"ISSN":["2379-5042"],"issn-type":[{"value":"2379-5042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,26]]},"assertion":[{"value":"2019-03-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00215-19"}}