{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T08:27:55Z","timestamp":1765960075789,"version":"3.41.2"},"reference-count":12,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T00:00:00Z","timestamp":1586304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,4,29]],"date-time":"2020-04-29T00:00:00Z","timestamp":1588118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mSphere"],"published-print":{"date-parts":[[2020,4,29]]},"abstract":"<jats:p>\n            Mary Lopez-Perez works on immunology and pathogenesis of malaria. In this mSphere of Influence article, she reflects on how the paper \u201cFunctional antibodies against VAR2CSA in nonpregnant populations from Colombia exposed to\n            <jats:named-content content-type=\"genus-species\">Plasmodium falciparum<\/jats:named-content>\n            and\n            <jats:named-content content-type=\"genus-species\">Plasmodium vivax<\/jats:named-content>\n            <jats:italic>\u201d<\/jats:italic>\n            by S. Gnidehou, J. Doritchamou, E. M. Arango, A. Cabrera, et al. (Infect Immun 82:2565\u22122573, 2014,\n            <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/doi.org\/10.1128\/IAI.01594-14\">https:\/\/doi.org\/10.1128\/IAI.01594-14<\/jats:ext-link>\n            ) made her cautious of relying exclusively on recombinant proteins when evaluating antibody responses.\n          <\/jats:p>","DOI":"10.1128\/msphere.00224-20","type":"journal-article","created":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T16:12:02Z","timestamp":1586275922000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":4,"title":["mSphere of Influence: Going Native, or the Risk of Overreliance on Recombinant Antigens"],"prefix":"10.1128","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9876-0248","authenticated-orcid":false,"given":"Mary","family":"Lopez-Perez","sequence":"first","affiliation":[{"name":"Centre for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.30875\/7e6f8c91-en"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/bs.apar.2015.02.004"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20041579"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001090050205"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(07)70022-1"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.12-0205"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-12-341"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-016-1125-9"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01594-14"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy467"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00136-18"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1712879115"}],"container-title":["mSphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSphere.00224-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSphere.00224-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T04:37:43Z","timestamp":1646714263000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mSphere.00224-20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,29]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,4,29]]}},"alternative-id":["10.1128\/mSphere.00224-20"],"URL":"https:\/\/doi.org\/10.1128\/msphere.00224-20","relation":{},"ISSN":["2379-5042"],"issn-type":[{"type":"electronic","value":"2379-5042"}],"subject":[],"published":{"date-parts":[[2020,4,29]]},"assertion":[{"value":"2020-04-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00224-20"}}