{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T10:17:43Z","timestamp":1777112263672,"version":"3.51.4"},"reference-count":43,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.usa.gov\/government-works"},{"start":{"date-parts":[[2017,12,27]],"date-time":"2017-12-27T00:00:00Z","timestamp":1514332800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mSphere"],"published-print":{"date-parts":[[2017,12,27]]},"abstract":"<jats:p>\n            <jats:italic>Salmonella<\/jats:italic>\n            is one of the most common causes of bacterial foodborne infections in the United States, and the Centers for Disease Control consider multidrug-resistant (MDR)\n            <jats:italic>Salmonella<\/jats:italic>\n            a \u201cSerious Threat Level pathogen.\u201d Because MDR\n            <jats:italic>Salmonella<\/jats:italic>\n            can lead to more severe disease in patients than that caused by antibiotic-sensitive strains, it is important to identify the role that antibiotics may play in enhancing\n            <jats:italic>Salmonella<\/jats:italic>\n            virulence. The current study examined several MDR\n            <jats:italic>Salmonella<\/jats:italic>\n            isolates and determined the effect that various antibiotics had on\n            <jats:italic>Salmonella<\/jats:italic>\n            motility, an important virulence-associated factor. While most antibiotics had a neutral or negative effect on motility, we found that kanamycin actually enhanced MDR\n            <jats:italic>Salmonella<\/jats:italic>\n            swarming in some isolates. Subsequent experiments showed this phenotype as being dependent on a combination of several different genetic factors. Understanding the influence that antibiotics have on MDR\n            <jats:italic>Salmonella<\/jats:italic>\n            motility is critical to the proper selection and prudent use of antibiotics for efficacious treatment while minimizing potential collateral consequences.\n          <\/jats:p>","DOI":"10.1128\/msphere.00306-17","type":"journal-article","created":{"date-parts":[[2017,11,2]],"date-time":"2017-11-02T00:25:33Z","timestamp":1509582333000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":44,"title":["Multidrug-Resistant Salmonella enterica Serovar Typhimurium Isolates Are Resistant to Antibiotics That Influence Their Swimming and Swarming Motility"],"prefix":"10.1128","volume":"2","author":[{"given":"Brian W.","family":"Brunelle","sequence":"first","affiliation":[{"name":"Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, ARS, USDA, Ames, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley L.","family":"Bearson","sequence":"additional","affiliation":[{"name":"Agroecosystems Management Research Unit, National Laboratory for Agriculture and the Environment, ARS, USDA, Ames, Iowa, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shawn M. 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