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We found that the\n            <jats:italic>H<\/jats:italic>\n            30 subset within\n            <jats:named-content content-type=\"genus-species\">E. coli<\/jats:named-content>\n            sequence type 131 (ST131-\n            <jats:italic>H<\/jats:italic>\n            30) is currently, and has been since at least 2004, the main\n            <jats:named-content content-type=\"genus-species\">E. coli<\/jats:named-content>\n            lineage contributing to key resistance phenotypes\u2014including extended-spectrum-beta-lactamase (ESBL) production, fluoroquinolone resistance, multidrug resistance, and dual ESBL production-plus-fluoroquinolone resistance\u2014at a United States tertiary care center with a rising prevalence of ESBL-producing\n            <jats:named-content content-type=\"genus-species\">E. coli<\/jats:named-content>\n            isolates. This identifies ST131-\n            <jats:italic>H<\/jats:italic>\n            30 as a target for diagnostic tests and preventive measures designed to curb the emergence of multidrug-resistant\n            <jats:named-content content-type=\"genus-species\">E. coli<\/jats:named-content>\n            isolates and\/or to blunt its clinical impact.\n          <\/jats:p>","DOI":"10.1128\/msphere.00314-16","type":"journal-article","created":{"date-parts":[[2016,11,24]],"date-time":"2016-11-24T03:00:27Z","timestamp":1479956427000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":11,"title":["Escherichia coli Sequence Type 131\n            <i>H<\/i>\n            30 Is the Main Driver of Emerging Extended-Spectrum-\u03b2-Lactamase-Producing E. coli at a Tertiary Care Center"],"prefix":"10.1128","volume":"1","author":[{"given":"James R.","family":"Johnson","sequence":"first","affiliation":[{"name":"VA Medical Center, Minneapolis, Minnesota, USA"},{"name":"University of Minnesota, Minneapolis, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Johnston","sequence":"additional","affiliation":[{"name":"VA Medical Center, Minneapolis, Minnesota, USA"},{"name":"University of Minnesota, Minneapolis, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Thuras","sequence":"additional","affiliation":[{"name":"VA Medical Center, Minneapolis, Minnesota, USA"},{"name":"University of Minnesota, Minneapolis, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryn","family":"Launer","sequence":"additional","affiliation":[{"name":"Los Angeles BioMedical Research Center at Harbor\u2013Harbor-UCLA Medical Center, Torrance, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgeni V.","family":"Sokurenko","sequence":"additional","affiliation":[{"name":"University of Washington, Seattle, Washington, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loren G.","family":"Miller","sequence":"additional","affiliation":[{"name":"Los Angeles BioMedical Research Center at Harbor\u2013Harbor-UCLA Medical Center, Torrance, California, USA"},{"name":"University of California, Los Angeles, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1286-4579(03)00049-2"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.6.5.657"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2209.160148"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00297-09"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00984-13"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1322678111"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00125-13"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit503"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofw002"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00119-14"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1086\/320196"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.06120-11"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1711.110488"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011265"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.UTI-0006-2012"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-33-1-23"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.6.1913-1923.2002"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00640-08"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw193"},{"key":"e_1_3_2_21_2","volume-title":"Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard, 9th ed (M07-A9)","author":"Clinical and Laboratory Standards Institute","year":"2012","unstructured":"Clinical and Laboratory Standards Institute . 2012. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard, 9th ed (M07-A9). 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