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Aneuploidy and LOH can also be induced during laboratory manipulations, such as during genetic transformation. We find that\n            <jats:named-content content-type=\"genus-species\">C. albicans<\/jats:named-content>\n            strain SN152, commonly used to generate gene deletions, has undergone a major LOH event on chromosome 2. One deletion strain generated in this background has acquired extra copies of chromosomes 5 and 7. We find that trisomy (three copies) of chromosome 7 is associated with sensitivity to fatty acids.\n          <\/jats:p>","DOI":"10.1128\/msphere.00402-19","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T11:48:59Z","timestamp":1561463339000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":9,"title":["Susceptibility to Medium-Chain Fatty Acids Is Associated with Trisomy of Chromosome 7 in\n            <i>Candida albicans<\/i>"],"prefix":"10.1128","volume":"4","author":[{"given":"Qinxi","family":"Ma","sequence":"first","affiliation":[{"name":"School of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Belfield, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2612-7678","authenticated-orcid":false,"given":"Mihaela","family":"Ola","sequence":"additional","affiliation":[{"name":"School of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Belfield, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5219-4298","authenticated-orcid":false,"given":"Elise","family":"Iracane","sequence":"additional","affiliation":[{"name":"School of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Belfield, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1770-5301","authenticated-orcid":false,"given":"Geraldine","family":"Butler","sequence":"additional","affiliation":[{"name":"School of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Belfield, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.108.090878"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1142210"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature09529"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1206412"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00060-10"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1128242"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.9.5150"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myv002"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2008.06176.x"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00516-13"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.000478"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msz104"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/aac.2.1.23"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.plipres.2007.10.002"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.78.6.788-791.1959"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01297-07"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.5414\/CP202460"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/aac.44.10.2873-2875.2000"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000783"},{"key":"e_1_3_4_21_2","first-page":"544","article-title":"Comparison between undecylenic acid and tolnaftate in the treatment of tinea pedis","volume":"25","author":"Fuerst JF","year":"1980","unstructured":"Fuerst JF, Cox GF, Weaver SM, Duncan WC. 1980. 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