{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T16:30:22Z","timestamp":1779208222793,"version":"3.51.4"},"reference-count":34,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2018,11,7]],"date-time":"2018-11-07T00:00:00Z","timestamp":1541548800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2018,12,26]],"date-time":"2018-12-26T00:00:00Z","timestamp":1545782400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100000923","name":"Department of Education and Training | Australian Research Council","doi-asserted-by":"publisher","award":["LP130100736"],"award-info":[{"award-number":["LP130100736"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mSphere"],"published-print":{"date-parts":[[2018,12,26]]},"abstract":"<jats:p>\n            <jats:named-content content-type=\"genus-species\">Staphylococcus pseudintermedius<\/jats:named-content>\n            is a significant veterinary pathogen and occasional cause of infections in humans. \u03b2-Lactams are an important group of antimicrobials used to treat staphylococcal infections in humans and animals. However, when staphylococci become methicillin resistant via the acquisition of a mobile genetic element called staphylococcal cassette chromosome\n            <jats:italic>mec<\/jats:italic>\n            (SCC\n            <jats:italic>mec<\/jats:italic>\n            ), they become resistant to all \u03b2-lactams. This study detected a novel SCC\n            <jats:italic>mec<\/jats:italic>\n            element among a cluster of methicillin-resistant\n            <jats:named-content content-type=\"genus-species\">S. pseudintermedius<\/jats:named-content>\n            isolates from animals in Australia. It also detected SCC\n            <jats:italic>mec<\/jats:italic>\n            elements in\n            <jats:named-content content-type=\"genus-species\">S. pseudintermedius<\/jats:named-content>\n            that had high similarity to those identified in methicillin-resistant\n            <jats:named-content content-type=\"genus-species\">Staphylococcus aureus<\/jats:named-content>\n            , demonstrating how human and animal pathogens can share the same resistance determinants.\n          <\/jats:p>","DOI":"10.1128\/msphere.00491-18","type":"journal-article","created":{"date-parts":[[2018,11,6]],"date-time":"2018-11-06T10:48:22Z","timestamp":1541501302000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":25,"title":["Characterization of Staphylococcal Cassette Chromosome\n            <i>mec<\/i>\n            Elements from Methicillin-Resistant\n            <i>Staphylococcus pseudintermedius<\/i>\n            Infections in Australian Animals"],"prefix":"10.1128","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8713-7189","authenticated-orcid":false,"given":"Kate A.","family":"Worthing","sequence":"first","affiliation":[{"name":"Sydney School of Veterinary Science, University of Sydney, NSW, Australia"},{"name":"Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, VIC, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sybille","family":"Schwendener","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Bacteriology, University of Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5722-9445","authenticated-orcid":false,"given":"Vincent","family":"Perreten","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Bacteriology, University of Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sugiyono","family":"Saputra","sequence":"additional","affiliation":[{"name":"Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, SA, Australia"},{"name":"Research Center for Biology, Indonesian Institute of Sciences, Bogor, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geoffrey W.","family":"Coombs","sequence":"additional","affiliation":[{"name":"Australia Antimicrobial Resistance and Infectious Diseases Laboratory, School of Veterinary Life Sciences, Murdoch University, Murdoch, WA, Australia"},{"name":"PathWest Laboratory Medicine\u2014WA, Fiona Stanley Hospital, Murdoch, WA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanley","family":"Pang","sequence":"additional","affiliation":[{"name":"Australia Antimicrobial Resistance and Infectious Diseases Laboratory, School of Veterinary Life Sciences, Murdoch University, Murdoch, WA, Australia"},{"name":"PathWest Laboratory Medicine\u2014WA, Fiona Stanley Hospital, Murdoch, WA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6141-5179","authenticated-orcid":false,"given":"Mark R.","family":"Davies","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, VIC, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Abraham","sequence":"additional","affiliation":[{"name":"Australia Antimicrobial Resistance and Infectious Diseases Laboratory, School of Veterinary Life Sciences, Murdoch University, Murdoch, WA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darren J.","family":"Trott","sequence":"additional","affiliation":[{"name":"Australian Centre for Antimicrobial Resistance Ecology, School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, SA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0003-6930","authenticated-orcid":false,"given":"Jacqueline M.","family":"Norris","sequence":"additional","affiliation":[{"name":"Sydney School of Veterinary Science, University of Sydney, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01599"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2016.05.008"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.28.3.397"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70126-8"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2402.171074"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.6.1549-1555.2000"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00575-09"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00579-09"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw317"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02268-15"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00738-13"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02255-07"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq078"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2017.11.022"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.01194-16"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.11.4289-4294.2002"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2013.02.005"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/1348-0421.12401"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2017.11.018"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0176379"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgar.2015.08.002"},{"key":"e_1_3_2_23_2","volume-title":"Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals; approved standard","author":"CLSI","year":"2013","unstructured":"CLSI. 2013. Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals; approved standard\u20144th ed. CLSI, Wayne, PA, USA.","edition":"4"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2009.06.029"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki306"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.01011-15"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00773-16"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu153"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.7.2637-2651.2004"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00951-10"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.01436"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.23.6862-6868.2001"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02621-12"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2011.03.026"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr039"}],"container-title":["mSphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSphere.00491-18","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSphere.00491-18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T04:17:29Z","timestamp":1646713049000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mSphere.00491-18"}},"subtitle":[],"editor":[{"given":"Paul D.","family":"Fey","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2018,12,26]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,12,26]]}},"alternative-id":["10.1128\/mSphere.00491-18"],"URL":"https:\/\/doi.org\/10.1128\/msphere.00491-18","relation":{},"ISSN":["2379-5042"],"issn-type":[{"value":"2379-5042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,26]]},"assertion":[{"value":"2018-09-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00491-18"}}