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Here it is shown that genetic deletion of either PRP1, its PGM2 ortholog, or both genes is dispensable for the parasite\u2019s lytic cycle, including host cell egress and invasion. Depletion of the proteins abrogated high Ca\n                    <jats:sup>2+<\/jats:sup>\n                    -mediated microneme secretion induced by the ionophore A23187; however, the constitutive and phosphatidic acid-mediated release remained unaffected. Secretion mediated by the former pathway is not essential for tachyzoite survival or acute\n                    <jats:italic>in vivo<\/jats:italic>\n                    infection in the mice.\n                  <\/jats:p>","DOI":"10.1128\/msphere.00521-17","type":"journal-article","created":{"date-parts":[[2017,12,13]],"date-time":"2017-12-13T16:09:07Z","timestamp":1513181347000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["Two Phosphoglucomutase Paralogs Facilitate Ionophore-Triggered Secretion of the\n                    <i>Toxoplasma<\/i>\n                    Micronemes"],"prefix":"10.1128","volume":"2","author":[{"given":"Sudeshna","family":"Saha","sequence":"first","affiliation":[{"name":"Department of Biology, Boston College, Chestnut Hill, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley I.","family":"Coleman","sequence":"additional","affiliation":[{"name":"Department of Biology, Boston College, Chestnut Hill, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi","family":"Dubey","sequence":"additional","affiliation":[{"name":"Department of Biology, Boston College, Chestnut Hill, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ira J.","family":"Blader","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University at Buffalo School of Medicine, Buffalo, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc-Jan","family":"Gubbels","sequence":"additional","affiliation":[{"name":"Department of Biology, Boston College, Chestnut Hill, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16412-X"},{"key":"e_1_3_2_3_2","first-page":"140","volume-title":"Infectious diseases of the fetus and newborn infant","author":"Remington JS","year":"1995","unstructured":"Remington JS McLeod R Desmonts G . 1995. 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