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Our work showed that the anterior nares could be an important reservoir for potential sinus pathobionts. This has implications for the diagnosis, prevention, and treatment of CRS. In addition, we found a potential pathogenic role for the\n                    <jats:named-content content-type=\"genus-species\">Corynebacterium tuberculostearicum<\/jats:named-content>\n                    ,\n                    <jats:named-content content-type=\"genus-species\">Haemophilus influenzae\/H. aegyptius<\/jats:named-content>\n                    , and\n                    <jats:italic>Staphylococcus<\/jats:italic>\n                    taxa and a potential beneficial role for\n                    <jats:italic>Dolosigranulum<\/jats:italic>\n                    . Finally, a decreased microbiome diversity was observed in patients with chronic rhinosinusitis without nasal polyps compared to that in healthy controls but not in chronic rhinosinusitis patients with nasal polyps. This suggests a potential role for the microbiome in disease development or progression of mainly this phenotype.\n                  <\/jats:p>","DOI":"10.1128\/msphere.00532-19","type":"journal-article","created":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T06:12:23Z","timestamp":1574748743000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":73,"title":["Anterior Nares Diversity and Pathobionts Represent Sinus Microbiome in Chronic Rhinosinusitis"],"prefix":"10.1128","volume":"4","author":[{"given":"Ilke","family":"De Boeck","sequence":"first","affiliation":[{"name":"University of Antwerp, Department of Bioscience Engineering, Antwerp, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3913-5677","authenticated-orcid":false,"given":"Stijn","family":"Wittouck","sequence":"additional","affiliation":[{"name":"University of Antwerp, Department of Bioscience Engineering, Antwerp, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8741-8252","authenticated-orcid":false,"given":"Katleen","family":"Martens","sequence":"additional","affiliation":[{"name":"University of Antwerp, Department of Bioscience Engineering, Antwerp, Belgium"},{"name":"KU Leuven, Department of Microbiology and Immunology, Research Group Allergy and Clinical Immunology, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos","family":"Claes","sequence":"additional","affiliation":[{"name":"Antwerp University Hospital, ENT, Head and Neck Surgery, Edegem, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Jorissen","sequence":"additional","affiliation":[{"name":"Clinical Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0358-9362","authenticated-orcid":false,"given":"Brecht","family":"Steelant","sequence":"additional","affiliation":[{"name":"KU Leuven, Department of Microbiology and Immunology, Research Group Allergy and Clinical Immunology, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne F. 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