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Despite its obvious medical relevance, timely diagnosis and efficient antifungal treatment of\n                    <jats:named-content content-type=\"genus-species\">A. fumigatus<\/jats:named-content>\n                    infection remain major challenges. Proteins on the surface of conidia (asexually produced spores) and mycelium directly mediate host-pathogen interaction and also may serve as targets for diagnosis and immunotherapy. However, the similarity of protein sequences between\n                    <jats:named-content content-type=\"genus-species\">A. fumigatus<\/jats:named-content>\n                    and other organisms, sometimes even including the human host, makes selection of targets for immunological-based studies difficult. Here, using surface protein biotinylation coupled with LC-MS\/MS analysis, we identified hundreds of\n                    <jats:named-content content-type=\"genus-species\">A. fumigatus<\/jats:named-content>\n                    surface proteins with exposed regions, further defining putative targets for possible diagnostic and immunotherapeutic design.\n                  <\/jats:p>","DOI":"10.1128\/msphere.00535-20","type":"journal-article","created":{"date-parts":[[2020,8,18]],"date-time":"2020-08-18T09:45:20Z","timestamp":1597743920000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":21,"title":["Biotinylated Surfome Profiling Identifies Potential Biomarkers for Diagnosis and Therapy of Aspergillus fumigatus Infection"],"prefix":"10.1128","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7958-6187","authenticated-orcid":false,"given":"Lei-Jie","family":"Jia","sequence":"first","affiliation":[{"name":"Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology\u2014Hans Kn\u00f6ll Institute, Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8984-3853","authenticated-orcid":false,"given":"Thomas","family":"Kr\u00fcger","sequence":"additional","affiliation":[{"name":"Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology\u2014Hans Kn\u00f6ll Institute, Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew G.","family":"Blango","sequence":"additional","affiliation":[{"name":"Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology\u2014Hans Kn\u00f6ll Institute, Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdinand","family":"von Eggeling","sequence":"additional","affiliation":[{"name":"Jena University Hospital, Department of Otolaryngology, Jena, Germany"},{"name":"Jena University Hospital, Core Unit Proteome Analysis, Jena, Germany"},{"name":"Jena University Hospital, DFG Core Unit Jena Biophotonic and Imaging Laboratory (JBIL), Jena, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9493-6402","authenticated-orcid":false,"given":"Olaf","family":"Kniemeyer","sequence":"additional","affiliation":[{"name":"Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology\u2014Hans Kn\u00f6ll Institute, Jena, Germany"},{"name":"Department of Microbiology and Molecular Biology, Institute of Microbiology, Friedrich Schiller University, Jena, 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