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There is a need for novel and more potent antifungal therapeutics. Consequently, we investigated a mixed library of drug-like and probe-like compounds with activity in\n            <jats:italic>Plasmodium<\/jats:italic>\n            spp. for activity against two common fungal pathogens,\n            <jats:named-content content-type=\"genus-species\">Cryptococcus neoformans<\/jats:named-content>\n            and\n            <jats:named-content content-type=\"genus-species\">Candida albicans<\/jats:named-content>\n            , along with two less common pathogenic species,\n            <jats:italic>Lomentospora prolificans<\/jats:italic>\n            and\n            <jats:named-content content-type=\"genus-species\">Cryptococcus gattii<\/jats:named-content>\n            . We uncover a previously uncharacterized drug with higher broad-spectrum antifungal activity than some current treatments. Our findings may eventually lead to a compound added to the arsenal of antifungal therapeutics.\n          <\/jats:p>","DOI":"10.1128\/msphere.00537-17","type":"journal-article","created":{"date-parts":[[2018,3,13]],"date-time":"2018-03-13T13:04:09Z","timestamp":1520946249000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["Novel Antifungal Compounds Discovered in Medicines for Malaria Venture\u2019s Malaria Box"],"prefix":"10.1128","volume":"3","author":[{"given":"Eric H.","family":"Jung","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA"},{"name":"Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Meyers","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Bosch","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA"},{"name":"Division of Pulmonology and Allergy\/Immunology, Case Western Reserve University, Cleveland, Ohio, USA"},{"name":"InterRayBio, LLC, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9402-9167","authenticated-orcid":false,"given":"Arturo","family":"Casadevall","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA"},{"name":"Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4733.2002.51108.x"},{"key":"e_1_3_2_3_2","volume-title":"World Bank policy research working paper no. 6719","author":"Lakner C","year":"2013","unstructured":"Lakner C, Milanovic B. 2013. 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