{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:00:15Z","timestamp":1753880415584,"version":"3.41.2"},"reference-count":3,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2019,8,21]],"date-time":"2019-08-21T00:00:00Z","timestamp":1566345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T00:00:00Z","timestamp":1566950400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["mSphere"],"published-print":{"date-parts":[[2019,8,28]]},"abstract":"<jats:p>\n            Jorge Amich studies several aspects of sulfur and nitrogen metabolism in\n            <jats:named-content content-type=\"genus-species\">Aspergillus fumigatus<\/jats:named-content>\n            , with the ultimate aim of identifying targets for the development of novel antifungals. In this mSphere of Influence article, he reflects on how \u201cSub-Telomere Directed Gene Expression during Initiation of Invasive Aspergillosis\u201d (A. McDonagh, N. D. Fedorova, J. Crabtree, Y. Yu, S. Kim, et al., PLoS Pathog 4:e1000154, 2008,\n            <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/doi.org\/10.1371\/journal.ppat.1000154\">https:\/\/doi.org\/10.1371\/journal.ppat.1000154<\/jats:ext-link>\n            ) impacted his thinking about\n            <jats:italic>in vivo<\/jats:italic>\n            metabolism and how to investigate it.\n          <\/jats:p>","DOI":"10.1128\/msphere.00566-19","type":"journal-article","created":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T10:58:18Z","timestamp":1566298698000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":3,"title":["mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses"],"prefix":"10.1128","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8987-5115","authenticated-orcid":false,"given":"Jorge","family":"Amich","sequence":"first","affiliation":[{"name":"Manchester Fungal Infection Group (MFIG), Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000154"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00348-09"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12238"}],"container-title":["mSphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSphere.00566-19","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/mSphere.00566-19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,8]],"date-time":"2022-03-08T04:22:44Z","timestamp":1646713364000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/mSphere.00566-19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,28]]},"references-count":3,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,8,28]]}},"alternative-id":["10.1128\/mSphere.00566-19"],"URL":"https:\/\/doi.org\/10.1128\/msphere.00566-19","relation":{},"ISSN":["2379-5042"],"issn-type":[{"type":"electronic","value":"2379-5042"}],"subject":[],"published":{"date-parts":[[2019,8,28]]},"assertion":[{"value":"2019-08-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00566-19"}}